- Burn Injury Management and Outcomes
- Wound Healing and Treatments
- Shoulder and Clavicle Injuries
- Shoulder Injury and Treatment
- Pediatric Pain Management Techniques
- Thermal Regulation in Medicine
- Asthma and respiratory diseases
- Sexual Differentiation and Disorders
- Nerve Injury and Rehabilitation
- Sexual function and dysfunction studies
- Pancreatic function and diabetes
- CNS Lymphoma Diagnosis and Treatment
- Pressure Ulcer Prevention and Management
- Planarian Biology and Electrostimulation
- Gestational Trophoblastic Disease Studies
- Bladder and Urothelial Cancer Treatments
- Ultrasound in Clinical Applications
- Medical History and Research
- Coronary Artery Anomalies
- Trauma Management and Diagnosis
- Reliability and Agreement in Measurement
- Orthopedic Infections and Treatments
- Gastrointestinal Bleeding Diagnosis and Treatment
- Ion Transport and Channel Regulation
- Advancements in Transdermal Drug Delivery
Colorado Permanente Medical Group
2024
Mayo Clinic in Arizona
2022-2023
University Medical Center New Orleans
2023
Bridgeport Hospital
2023
Georgetown University
2023
MedStar Health
2023
Louisiana State University Health Sciences Center New Orleans
2023
Medical University of South Carolina
2023
Mayo Clinic in Florida
2022-2023
Jacksonville College
2022
We report the cloning, sequence analysis, tissue distribution, functional expression, and chromosomal localization of human pancreatic sodium bicarbonate cotransport protein (pancreatic NBC (pNBC)). The transporter was identified by searching expressed tag data base. An I.M.A.G.E. clone W39298 identified, a polymerase chain reaction probe generated to screen pancreas cDNA library. pNBC encodes 1079-residue polypeptide that differs at N terminus from recently cloned cotransporter isolated...
Early excision and autografting are standard care for deeper burns. However, donor sites a source of significant morbidity. To address this, the ReCell® Autologous Cell Harvesting Device (ReCell) was designed use at point-of-care to prepare noncultured, autologous skin cell suspension (ASCS) capable epidermal regeneration using minimal skin. A prospective study conducted evaluate clinical performance ReCell vs meshed split-thickness grafts (STSG, Control) treatment deep partial-thickness...
Background: Although deviations in scapular orientation are thought to predispose shoulder injuries throwing athletes, the biomechanical mechanism underlying athletes with an altered remains unclear. Methods: Seven fresh-frozen cadaveric shoulders were evaluated at 90° of abduction, humerus externally rotated from maximum angle, simulate late cocking phase motion. Loads applied deltoid, pectoralis major, latissimus dorsi, teres and all rotator cuff muscles. Contact pressure glenohumeral...
Importance There was a shift in patient volume from in-person to video telemedicine visits during the COVID-19 pandemic. Objective To determine concordance of provisional diagnoses established at visit with an for patients presenting new clinical problem. Design, Setting, and Participants This is diagnostic study who underwent consultation followed by outpatient same problem specialty within 90-day window. The diagnosis made compared reference standard 2 blinded, independent medical...
Complete repair in massive rotator cuff tear may not be possible, allowing for only partial repair. However, the effect of on glenohumeral biomechanics has been evaluated. Therefore, purpose this study was to compare rotational range motion (ROM), kinematics, and gap formation at repaired tendon edge following according degree completion.Posterior fixation will restore altered tear.Controlled laboratory study.Eight cadaveric shoulders were tested 0°, 30°, 60° abduction scapular plane. Muscle...
Pain and itch symptoms are common after major thermal burn injury (MThBI)-requiring tissue autografting. To our knowledge, no prospective longitudinal studies have characterized pain outcomes autografting associations between functional interference caused by such symptoms.We prospectively evaluated graft site donor severity (0 to 10, numeric rating scale) over 1 year among a representative cohort of MThBI survivors (n=96) who received within 14 days MThBI.Nearly all participants had...
Results of previous studies suggest that β-adrenoreceptor activation may augment pain, and antagonists be effective in reducing particularly individuals not homozygous for the catechol-O-methyltransferase (COMT) high-activity haplotype.Consenting patients admitted thermal burn injury at participating centers were genotyped; those who COMT homozygotes randomized to propranolol 240 mg/d or placebo. Primary outcomes study feasibility (consent rate, protocol completion rate) pain scores on days...
Increasing evidence suggests that stress system activation after burn injury may contribute to burn-related pain. If this is the case, then genetic variations influencing function of important components, such as enzyme catechol-O-methyltransferase (COMT), predict pain severity thermal injury. The authors evaluated association between COMT genotype and intensity in 57 individuals hospitalized Consenting participants at four centers were genotyped completed daily 0 10 numeric rating scale...
More than half of individuals experiencing major thermal burn injury (MThBI) receive an autologous skin graft (autograft), in which is removed from a healthy "donor" site and transplanted to the site. Persistent pain itch at are causes suffering disability MThBI survivors. African Americans have higher risk MThBI, other clinical settings experience greater burden relative European Americans. However, our knowledge, ethnic differences outcomes after not been assessed. We evaluated severity...
Abstract Approximately three quarters of major thermal burn injury (MThBI) survivors suffer from hypertrophic scarring (HTS) and over half experience chronic pain or itch. In MThBI, HTS itch are considered one the greatest unmet challenges postburn care psychosocial reintegration. Although scarring, itch, have been clinically associated, there no prospective, multisite studies examining tissue autograft site scar outcomes. The authors collected a representative cohort (n = 56) MThBI who...
Atelectasis is a significant risk factor for the development of pneumonia, especially in pediatric populations more prone to alveolar collapse or those who may have weakened muscular tone. The Metaneb system pneumatic, noninvasive physiotherapy technique that delivers chest high-frequency oscillations. Chest oscillations been shown enhance mucociliary clearance secretions and help resolve patchy atelectasis. This report describes case 17-year-old female patient developed left-sided...
Case: The patient sustained a pathologic fracture through chronic osteomyelitis of the tibia. Treatment involved resection bone and soft tissue, leaving 15-cm diaphyseal tibial defect. We designed construct to allow for trifocal transport using magnetic intramedullary lengthening nail connected cables. This technique uses cables secured proximal tibia, nail, segments. Conclusion: case details successful use cable-assisted nail. can successfully be used reconstruct defects that are longer...
Background Rotator cuff tendinopathy (RCT) is a frequently encountered condition by the orthopedic surgeon. Patients presenting with or partial thickness tear present difficult challenge to treat. Treatments for rotator include nonsurgical and surgical intervention. While management can be effective in treatment of RCT, patients must willing accept risks anesthesia surgery potentially undergo lengthy post-operative rehabilitation course. Our study evaluates use percutaneous ultrasonic...
<div>Abstract<p><b>Purpose:</b> We evaluated a novel therapy for primary central nervous system lymphoma (PCNSL) with induction immunochemotherapy high-dose methotrexate, temozolomide, and rituximab (MT-R) followed by intensive consolidation infusional etoposide cytarabine (EA). In addition, we the prognostic value of minimum apparent diffusion coefficient (ADC<sub>min</sub>) derived from diffusion-weighted MRI (DW-MRI) in patients treated this...