Hasan Bashir

ORCID: 0000-0003-4362-1897
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About
Contact & Profiles
Research Areas
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Nonmelanoma Skin Cancer Studies
  • Infectious Diseases and Mycology
  • Skin and Cellular Biology Research
  • Corneal Surgery and Treatments
  • Wnt/β-catenin signaling in development and cancer
  • Social Media in Health Education
  • RNA Research and Splicing
  • Skin Protection and Aging
  • bioluminescence and chemiluminescence research
  • Fungal Plant Pathogen Control
  • Hedgehog Signaling Pathway Studies
  • Immunotherapy and Immune Responses
  • Neonatal and fetal brain pathology
  • Cancer Cells and Metastasis
  • Telemedicine and Telehealth Implementation
  • Retinopathy of Prematurity Studies
  • COVID-19 and healthcare impacts
  • Melanoma and MAPK Pathways
  • Wound Healing and Treatments
  • Nuclear Structure and Function
  • Knowledge Management and Sharing
  • Developmental Biology and Gene Regulation
  • Antimicrobial agents and applications
  • Plant Disease Resistance and Genetics

Korea National University of Transportation
2025

Ocular Immunology and Uveitis Foundation
2024

Massachusetts Eye Research and Surgery Institute
2024

University of Pennsylvania
2009-2023

Johnson University
2022-2023

Rutgers, The State University of New Jersey
2022-2023

Rutgers Sexual and Reproductive Health and Rights
2022

Penn Presbyterian Medical Center
2017-2018

Philadelphia University
2017

Src family tyrosine kinases (SFK) regulate cell proliferation, and increased SFK activity is common in human carcinomas, including cutaneous squamous carcinomas (SCC) its precursors. The elevated SCCs was modeled using K14-Fyn Y528F transgenic mice, which spontaneously form punctate keratotic lesions, scaly plaques, large tumors resembling actinic keratoses, SCC situ, SCCs, respectively. Lesional tissue showed levels of activated SFKs, PDK1, STAT3, ERK1/2, whereas Notch1/NICD protein...

10.1158/0008-5472.can-09-2976 article EN Cancer Research 2009-11-25

This study aims to elucidate the genomic characteristics of Bacillus subtilis MGE 2012, a strain isolated from Korean traditional fermented food, meju, which contributes its high enzyme activity and potential applications. The whole genome sequence B. 2012 was assembled using MEGAHIT, annotated RAST BLASTKOALA v3.1. Phylogenetic analysis placed within clade, showing similarity NCIB 3610 ATCC 6051. AntiSMASH identified 14 biosynthetic gene clusters (BGCs) capable producing various secondary...

10.3390/pr13051503 article EN Processes 2025-05-14

Cutaneous squamous cell carcinoma (cSCC) is the second most common form of skin cancer and associated with cumulative UV exposure. Studies have shown that prolonged voriconazole use promotes cSCC formation; however, biological mechanisms responsible for increased incidence remain unclear. Here, we show directly increases oxidative stress in human keratinocytes UV-induced DNA damage as determined by comet assay, 8-oxoguanine immunofluorescence mass spectrometry. Voriconazole treatment...

10.1111/exd.14038 article EN Experimental Dermatology 2019-09-13

Abstract: PURPOSE: The purpose of the study was to efficacy oral cyclophosphamide monotherapy in advanced resistant ocular cicatricial pemphigoid (OCP). MATERIALS AND METHODS: This retrospective case series examines patients diagnosed with OCP at a uveitis tertiary care center who were treated therapy. RESULTS: Seventeen included this study. average age participants 74.3 ± 10.3 years, ranging from 60 99 years. gender distribution 8 females 9 males. Oral cyclophosphamide-induced remission 7...

10.4103/tjo.tjo-d-24-00057 article EN cc-by-nc-sa Taiwan Journal of Ophthalmology 2024-11-06

OBJECTIVES/GOALS: While CTSA hubs have contributed to the successes in COVID-19 clinical research, understanding role of consortium translating vaccine efficacy and availability awareness implementation. The goal this study is quantitatively assess use social media dissemination COVID 19 content across 60+ Hubs. METHODS/STUDY POPULATION: Structured search terms Search Solutions database were used identify Hub website pages highlighting “COVID-19 Vaccination Information.” Each link identified...

10.1017/cts.2022.146 article EN cc-by-nc-nd Journal of Clinical and Translational Science 2022-04-01

<div>Abstract<p>Src family tyrosine kinases (SFK) regulate cell proliferation, and increased SFK activity is common in human carcinomas, including cutaneous squamous carcinomas (SCC) its precursors. The elevated SCCs was modeled using K14-Fyn Y528F transgenic mice, which spontaneously form punctate keratotic lesions, scaly plaques, large tumors resembling actinic keratoses, SCC <i>in situ</i>, SCCs, respectively. Lesional tissue showed levels of activated SFKs, PDK1,...

10.1158/0008-5472.c.6500072.v1 preprint EN 2023-03-30

The aim of this research is to describe the use social media platform, Instagram, by academic ophthalmology residency programs in United States over time and consider impact COVID-19 pandemic on ophthalmology's presence.This cross-sectional study was conducted online reviewing publicly accessible Instagram accounts all accredited US programs.Number with an affiliated account were analyzed year creation. content top six most followers evaluating amount engagement within defined post...

10.2147/opth.s398170 article EN cc-by-nc Clinical ophthalmology 2023-06-01

<div>Abstract<p>Src family tyrosine kinases (SFK) regulate cell proliferation, and increased SFK activity is common in human carcinomas, including cutaneous squamous carcinomas (SCC) its precursors. The elevated SCCs was modeled using K14-Fyn Y528F transgenic mice, which spontaneously form punctate keratotic lesions, scaly plaques, large tumors resembling actinic keratoses, SCC <i>in situ</i>, SCCs, respectively. Lesional tissue showed levels of activated SFKs, PDK1,...

10.1158/0008-5472.c.6500072 preprint EN 2023-03-30

Cutaneous squamous cell carcinoma (cSCC) is the second most common cancer in humans, with an incidence of approximately 700,000 cases per year United States (Rogers et al., 2010Rogers H.W. Weinstock M.A. Harris A.R. Hinckley M.R. Feldman S.R. Fleischer A.B. al.Incidence estimate nonmelanoma skin States, 2006.Arch Dermatol. 2010; 146: 283-287Crossref PubMed Scopus (975) Google Scholar). It known that cSCC strongly associated sun exposure, specifically UVB and UVA, as well other risk factors,...

10.1016/j.jisp.2018.10.006 article EN publisher-specific-oa Journal of Investigative Dermatology Symposium Proceedings 2018-11-21
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