A5009510225- CAR-T cell therapy research
- Cancer Immunotherapy and Biomarkers
- Phagocytosis and Immune Regulation
- Virus-based gene therapy research
- Biomedical and Engineering Education
- Erythrocyte Function and Pathophysiology
- Radiopharmaceutical Chemistry and Applications
- Radiomics and Machine Learning in Medical Imaging
- Prostate Cancer Treatment and Research
- Medical Imaging Techniques and Applications
- Glioma Diagnosis and Treatment
- Sarcoma Diagnosis and Treatment
- Cell death mechanisms and regulation
- Integrated Circuits and Semiconductor Failure Analysis
- Prostate Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Medical Imaging and Pathology Studies
- Cytomegalovirus and herpesvirus research
- HER2/EGFR in Cancer Research
- Biomedical Ethics and Regulation
- Viral Infectious Diseases and Gene Expression in Insects
- Immunotherapy and Immune Responses
- Lymphoma Diagnosis and Treatment
- Transplantation: Methods and Outcomes
- Autophagy in Disease and Therapy
RefleXion Medical (United States)
2023-2025
Columbia University Irving Medical Center
2024
Memorial Sloan Kettering Cancer Center
2021-2023
Université Paris-Saclay
2017-2018
Institut Gustave Roussy
2017-2018
Inserm
2017
Abstract Even though cell death modalities elicited by anticancer chemotherapy and radiotherapy have been extensively studied, the ability of treatments to induce non-cell-autonomous has never investigated. By means multispectral imaging flow-cytometry-based technology, we analyzed lethal fate cancer cells that were treated with conventional agents co-cultured untreated cells, observing can simultaneously trigger cell-autonomous in cells. After ionizing radiation, oxaliplatin, or cisplatin...
e12575 Background: SCINTIX biology-guided radiotherapy (BgRT) uses F18-FDG emissions from lung and bone tumors to direct beamlets almost in real-time. Expanding BgRT indications with more specific radiotracers like F18-FES holds therapeutic promise. This study investigates PET imaging metrics estrogen receptor positive (ER+) breast cancer lesions for potential use. Methods: Ten FES PET/CT scans patients 16 ER+ total were retrospectively selected one institution. Eight of these also underwent...
Purpose/objective(s) Bridging radiation therapy (bRT) is increasingly being utilized prior to chimeric antigen receptor (CAR) T-cell for large B-cell lymphoma (LBCL). It unknown how the extent of cytoreduction during bRT impacts outcomes. Materials/methods We retrospectively reviewed patients with LBCL treated followed by CAR therapy. Metabolic tumor volume (MTV), maximum standardized uptake value (SUV max ), SUV mean , and total lesion glycolysis (TLG) were extracted from...
[18F]-FDG positron emission tomography with computed (PET/CT) imaging is widely used to enhance the quality of care in patients diagnosed cancer. Furthermore, it holds potential offer insight into synergic effect combining radiation therapy (RT) immuno-oncological (IO) agents. This achieved by evaluating treatment responses both at RT and distant tumor sites, thereby encompassing phenomenon known as abscopal effect. In this context, PET/CT can play an important role establishing timelines...