- Algebraic Geometry and Number Theory
- Inflammatory Bowel Disease
- Advanced Algebra and Geometry
- Geometry and complex manifolds
- Microscopic Colitis
- Geometric Analysis and Curvature Flows
- Autoimmune and Inflammatory Disorders
- Advanced Differential Equations and Dynamical Systems
- Polynomial and algebraic computation
- Homotopy and Cohomology in Algebraic Topology
- Commutative Algebra and Its Applications
- Immunodeficiency and Autoimmune Disorders
- Systemic Lupus Erythematosus Research
- Liver Diseases and Immunity
- Minimally Invasive Surgical Techniques
- Mathematical Dynamics and Fractals
- Finite Group Theory Research
- Celiac Disease Research and Management
- Esophageal and GI Pathology
- Eosinophilic Esophagitis
- Genetic factors in colorectal cancer
- Anesthesia and Pain Management
- Hernia repair and management
- Historical Studies and Socio-cultural Analysis
- Cytomegalovirus and herpesvirus research
University of Milan
2010-2025
Centre de Recerca Matemàtica
2023
Universitat de Barcelona
2023
University of Pavia
1990-2023
University of Insubria
2008-2022
Ospedale di Circolo e Fondazione Macchi
2013-2022
Mylan (Switzerland)
2012
Casa Sollievo della Sofferenza
2008-2011
Ospedale di Circolo di Busto Arsizio
2007-2011
University Hospital of Zurich
2011
Whether the duration of maintenance treatment with azathioprine (AZA) affects outcome ulcerative colitis (UC) is unclear. We investigated clinical outcomes and any predictive factors after withdrawal AZA in UC.In this multicenter observational retrospective study, 127 Italian UC patients, who were steroid-free remission at time AZA, followed-up for a median 55 months or until relapse. The frequency relapse colectomy was analyzed according to demographic, clinical, endoscopic variables.After...
Management of perianal and rectovaginal fistulae complicating Crohn's disease (CD) is unsatisfactory. Infliximab effective in the treatment fistulating CD. However, reopening frequent, suggesting persistence deep fistula tracts despite superficial healing. In this study, clinical endosonographic behavior were evaluated following infliximab infusions, as well role anal endosonography (AE) predicting their outcome.Thirty CD patients presenting with and/or received an infusion at a dose 5 mg/kg...
We study submanifolds of A_g that are totally geodesic for the locally symmetric metric and which contained in closure Jacobian locus but not its boundary. In first section we recall a formula second fundamental form period map due to Pirola, Tortora author. show this result can be stated quite neatly using line bundle over product curve with itself. give an upper bound dimension germ submanifold passing through [C] M_g terms gonality C. This yields locus, only depends on genus. also...
We study the local geometry of moduli space intermediate Jacobians (2,2) -threefolds in \mathbb{P}^{2} \times . More precisely, we prove that a composition second fundamental form Siegel metric \mathcal{A}_{9} restricted to this space, with natural multiplication map is nonzero holomorphic section vector bundle. also describe its kernel. use two conic bundle structures these threefolds, Prym theory, gaussian maps and Jacobian ideals.
OBJECTIVES: Several studies have investigated, with conflicting results, the risk factors for reoperation in Crohn's disease (CD) patients.CARD15gene variants been identified as a major genetic factor CD patients and associated ileal disease, stenosis, of surgery. However, data regarding association between these need are very few conflicting. This study evaluated reoperation, includingCARD15gene variants. METHODS: A total 253 consecutive patients, recruited four Italian tertiary-care...
We study the curvature of moduli space <inline-formula content-type="math/mathml"> <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" alttext="upper M Subscript g"> <mml:semantics> <mml:mrow class="MJX-TeXAtom-ORD"> <mml:msub> <mml:mi>M</mml:mi> <mml:mi>g</mml:mi> </mml:msub> </mml:mrow> <mml:annotation encoding="application/x-tex">{M_g}</mml:annotation> </mml:semantics> </mml:math> </inline-formula> curves genus alttext="g"> encoding="application/x-tex">g</mml:annotation> with Siegel...
The Second Gaussian MapWe first recall the definition of maps (cf.[23]).Let X be a smooth projective curve, let S := × X, and ⊂ diagonal.Let L line
Abstract Leukocytes are thought to play an important role in the pathogenesis of inflammatory bowel diseases; granulocyte–monocyte adsorptive (GMA) apheresis, extracorporeal technique aimed at removing activated circulating leukocytes from blood, may represent a safe and effective therapeutic tool these patients. The Italian Registry Therapeutic Apheresis performed observational, multicentric study involving 24 Gastroenterology Units. In this study, laboratory data clinical outcomes 230...
We study Shimura curves of PEL type in [Formula: see text] generically contained the Prym locus. both unramified locus, obtained using étale double covers, and ramified corresponding to covers at two points. In cases, we consider family all compatible with a fixed group action on base curve. restrict case where is one-dimensional quotient curve by text]. give simple criterion for image these families under map be Using computer algebra check examples this way up genus 28. obtain 43 locus 9...
The potential clinical implications of autoimmunity during treatment with infliximab are unclear.To determine the frequency and correlation autoantibody formation in patients Crohn's disease treated a routine setting.Sixty-three refractory/inflammatory (31) and/or fistulising (32), received an infusion at dose 5 mg/kg weeks 0, 2 6, were evaluated for development antinuclear, anti-double-stranded DNA, anti-Sm, anti-RNP, anti-SSA, anti-SSB antihistone antibodies. correlates pharmacological...