- Advanced MRI Techniques and Applications
- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Functional Brain Connectivity Studies
- Cardiac pacing and defibrillation studies
- Spaceflight effects on biology
- Traumatic Brain Injury and Neurovascular Disturbances
- Transcranial Magnetic Stimulation Studies
- Neurological Complications and Syndromes
- Spine and Intervertebral Disc Pathology
- Neurological disorders and treatments
- Moyamoya disease diagnosis and treatment
- Long-Term Effects of COVID-19
- Advanced X-ray and CT Imaging
- Blood disorders and treatments
- CNS Lymphoma Diagnosis and Treatment
- Spinal Fractures and Fixation Techniques
- Cerebrospinal fluid and hydrocephalus
- Pediatric health and respiratory diseases
- EEG and Brain-Computer Interfaces
- Cardiac Arrhythmias and Treatments
- Neural dynamics and brain function
- Radiation Dose and Imaging
- Spinal Dysraphism and Malformations
- Healthcare Policy and Management
Medical University of South Carolina
2015-2025
Stanford University
2014
University of Florida
2011-2012
Florida College
2012
There is limited information regarding the effects of spaceflight on anatomical configuration brain and cerebrospinal fluid (CSF) spaces.We used magnetic resonance imaging (MRI) to compare images 18 astronauts' brains before after missions long duration, involving stays International Space Station, 16 short participation in Shuttle Program. Images were interpreted by readers who unaware flight duration. We also generated paired preflight postflight MRI cine clips derived from...
Emerging evidence suggests that repetitive transcranial magnetic stimulation (rTMS) enhances cognition in mild cognitive impairment (MCI). Accelerated intermittent theta burst (iTBS) rTMS protocols are promising as they substantially reduce burden by shortening the treatment course, but safety, feasibility, and acceptability of iTBS have not been established MCI.
<h3>BACKGROUND AND PURPOSE:</h3> Severe ischemic changes are a rare but devastating complication following direct superficial temporal artery to MCA bypass in patients with Moyamoya disease. This study was undertaken determine whether preoperative MR imaging and/or cerebrovascular reserve assessment by using reference standard stable xenon-enhanced CT could predict such complications. <h3>MATERIALS METHODS:</h3> Among all adult undergoing at our institution between 2005 and 2010 who received...
Background: Published results of our Phase I safety and feasibility trial accelerated intermittent theta burst stimulation (a-iTBS) in mild cognitive impairment (MCI) due to Alzheimer's disease showed a large effect-size improvement cognition.Objective: Further demonstrate target engagement by identifying whether changes local network-level functional connectivity relate the observed improvement.Methods: Eighteen patients with MCI received 3-day a-iTBS (8 sessions/day) left dorsolateral...
Published results of our Phase I safety and feasibility trial accelerated intermittent theta burst stimulation (a-iTBS) in mild cognitive impairment (MCI) due to Alzheimer's disease showed a large effect-size improvement cognition. Further demonstrate target engagement by identifying whether changes local network-level functional connectivity relate the observed improvement. Eighteen patients with MCI received 3-day a-iTBS (8 sessions/day) left dorsolateral prefrontal cortex at Beam F3...
Abstract The centromedian nucleus of the thalamus (CMT) is a core arousal center with potential for enhancing cognitive attention. While emergent focused ultrasound can reach this area, stimulation paradigms which may enhance function in humans remain unknown. Here we performed bilateral CMT using novel neuromodulation wearable device 3 distinct pulse frequencies. We found that brief 25Hz enhanced reaction time directed attention Oddball task at least 40 minutes. Pre-post electrocortical EEG...
Recombinant human bone morphogenetic protein-2 (rhBMP-2) is responsible for multiple different signaling processes including positive effects on formation and fusion. In 2002, rhBMP-2 was approved use in anterior lumbar spinal fusion by the Food Drug Administration. Since that time, has become widespread. The of rh-BMP2 pediatric fusion, however, not been widely reported. We report experience at University Florida.Data patients under age 18 years who underwent with as an adjunct were...
<h3>BACKGROUND AND PURPOSE:</h3> Parallel imaging facilitates the acquisition of echo-planar images with a reduced TE, enabling incorporation an additional image at later TE. Here we investigated use parallel imaging–enhanced dual-echo EPI sequence to improve lesion conspicuity in diffusion-weighted imaging. <h3>MATERIALS METHODS:</h3> DWI data were acquired 50 consecutive patients suspected stroke 1.5T. The included 2 for 1 diffusion-preparation period (echo [TE = 48 ms] and echo 105 ms])....
Head congestion is one of the most common somatic symptoms experienced by astronauts during spaceflight; however, changes in opacification paranasal sinuses or mastoid air cells have not been adequately studied.To quantify preflight to postflight and Space Shuttle International Station (ISS) assess whether there are differences between 2 groups astronauts.This cohort study examined head magnetic resonance images (MRIs) 35 who had participated either a short-duration (≤30 days) mission...
Background Electric field (E-field) modeling is a valuable method of elucidating the cortical target engagement from transcranial magnetic stimulation (TMS) and electrical (tES), but it typically dependent on individual MRI scans. In this study, we systematically tested whether E-field models in template MNI-152 Ernie scans can reliably approximate group-level E-fields induced N = 195 individuals across 5 diagnoses (healthy, alcohol use disorder, tobacco anxiety, depression). Methods We...
Transient contrast enhancement on computed tomography following endovascular treatment of stroke is a recognized entity that has been previously reported. Technological advances in brain imaging now have the potential to explore and refine its proposed etiology. We describe three patients whom location correlates with decreased cerebral blood volume pre-therapeutic CT perfusion studies restricted diffusion MRI. In this regard, demarcated areas completed infarction. The diagnostic etiological...
Situated at the intersection of poetry, race, and politics, this collection exposes many various ways race informs American poetry. Contributors examine historical influence on critical reception evolution racial definitions archetypes. They take a fresh look influential overlooked figures who have shaped poetic dialogue about such as William S. Braithwaite, Gwendolyn Brooks, Robert Duncan, James Weldon Johnson, Bob Kaufman, Claude McKay, Harriet Monroe, Melvin B. Tolson, Jay Wright....
Abstract Background Repetitive transcranial magnetic stimulation enhances cognition in people with mild cognitive impairment (MCI). Whereas conventional treatment requires daily sessions for 4‐6 weeks, accelerated intermittent theta burst (iTBS) shortens the course to just 3 days, substantially improving feasibility of use MCI. We conducted a Phase I safety and trial iTBS MCI, finding preliminary evidence improvement. Here, we explore neural mechanism this effect by evaluating iTBS‐related...
Primary central nervous system posttransplant lymphoproliferative disorder is a rare complication of solid organ transplantation, with increasing incidence in children given steady rise pediatric transplants. Given similar imaging appearance to many opportunistic infections, high degree awareness required for prompt and early diagnosis. We report case primary presenting as single rim enhancing lesion restricted diffusion mimicking an intracranial abscess.