A5043159818- Microbial Community Ecology and Physiology
- Genomics and Phylogenetic Studies
- Marine Sponges and Natural Products
- Protist diversity and phylogeny
- Microbial Natural Products and Biosynthesis
- Synthesis and Biological Activity
- Seaweed-derived Bioactive Compounds
- Marine Biology and Ecology Research
- Geology and Paleoclimatology Research
- Food Industry and Aquatic Biology
- Pharmaceutical and Antibiotic Environmental Impacts
- Isotope Analysis in Ecology
- Genetics, Bioinformatics, and Biomedical Research
- Coral and Marine Ecosystems Studies
- Antibiotic Use and Resistance
- Diagnosis and treatment of tuberculosis
- Infectious Diseases and Tuberculosis
- Algal biology and biofuel production
- Tuberculosis Research and Epidemiology
- Gut microbiota and health
- Escherichia coli research studies
- Probiotics and Fermented Foods
- Bacteriophages and microbial interactions
- Biotechnology and Related Fields
- Insect symbiosis and bacterial influences
University of Cambridge
2022-2025
Okinawa Institute of Science and Technology Graduate University
2015-2024
Northumbria University
2024
Mauritius Institute of Education
2012-2014
The marine dinoflagellate, Symbiodinium, is a well-known photosynthetic partner for coral and other diverse, non-photosynthetic hosts in subtropical tropical shallows, where it comprises an essential component of ecosystems. Using molecular phylogenetics, the genus Symbiodinium has been classified into nine major clades, A-I, one reported differences among phenotypes their capacity to synthesize mycosporine-like amino acids (MAAs), which absorb UV radiation. However, genetic basis this...
Indian Ocean hydrothermal vents are believed to represent a novel biogeographic province, and host many genera families of animals, potentially indigenous systems. In particular, since its discovery in 2001, much attention has been paid so-called 'scaly-foot' gastropod because unique iron-sulfide-coated dermal sclerites the chemosynthetic symbioses various tissues. Despite increasing interest faunal assemblages at vents, only two vent fields have investigated Ocean. Here we report newly...
Photosynthetic dinoflagellates of the Family Symbiodiniaceae live symbiotically with many organisms that inhabit coral reefs and are currently classified into fifteen groups, including seven genera. Draft genomes from four genera, Symbiodinium, Breviolum, Fugacium, Cladocopium, which have been isolated corals, reported. However, no genome is available genus Durusdinium, occupies an intermediate phylogenetic position in well known for thermal tolerance (resistance to bleaching). We sequenced,...
Dispersal ability plays a key role in the maintenance of species spatially and temporally discrete niches deep-sea hydrothermal vent environments. On basis population genetic analyses eastern Pacific fields, dispersal animals mid-oceanic ridge systems generally appears to be constrained by geographical barriers such as trenches, transform faults, microplates. Four fields (the Kairei Edmond near Rodriguez Triple Junction, Dodo Solitaire Central Indian Ridge) have been discovered system Ocean....
Abstract Fluid chemistry and microbial community patterns in chimney habitats were investigated two hydrothermal fields located at the Central Indian Ridge. Endmember fluid of Solitaire field, ~3 km away from spreading center, was characterized by moderately high temperature (307°C), Cl depletion (489 m ), mildly acidic pH (≥4.40), low metal concentrations (Fe ≤ 105 μ Mn = 78 ). Chloride indicates that subseafloor source had undergone phase separation temperatures higher than ~390°C while...
The African BioGenome Project (AfricaBP) is a Pan-African initiative aimed at improving food systems and biodiversity conservation through genomics while ensuring equitable data sharing benefits. Open Institute the knowledge exchange platform of AfricaBP which aims to bridge local gaps in bioinformatics enable infrastructural developments. In 2024, advanced this mission by organising 31 workshops that attracted more than 3500 registered attendees trained 380 researchers genomics,...
Dinoflagellates are unicellular marine and freshwater eukaryotes. They possess large nuclear genomes (1.5-245 gigabases) produce structurally unique biologically active polyketide secondary metabolites. Although biosynthesis is well studied in terrestrial organisms, only recently have dinoflagellate polyketides been investigated. Transcriptomic analyses characterized synthase genes having single domains. The Genus Symbiodinium, with a comparatively small genome, group of major coral...
Abstract Symbiodiniaceae dinoflagellates possess smaller nuclear genomes than other and produce structurally specialized, biologically active, secondary metabolites. Till date, little is known about the evolution of metabolism in as comparative genomic approaches have been hampered by their large genome sizes. Here, we overcome this challenge combining metabolomics to investigate how chemical diversity arises three decoded (clades A3, B1 C). Our analyses identify extensive diversification...
Abstract Background Some dinoflagellates cause harmful algal blooms, releasing toxic secondary metabolites, to the detriment of marine ecosystems and human health. Our understanding dinoflagellate toxin biosynthesis has been hampered by their unusually large genomes. To overcome this challenge, for first time, we sequenced genome, microRNAs, mRNA isoforms a basal dinoflagellate, Amphidinium gibbosum , employed an integrated omics approach understand its metabolite biosynthesis. Results We...
Abstract Patients diagnosed with Alzheimer 's disease (AD) show a characteristic neurochemical deficit of acetylcholine, especially in the basal forebrains. The use acetylcholinesterase (AChE) inhibitors to retard hydrolysis acetylcholine has been suggested as promising strategy for AD treatment. In this study, we evaluated inhibitory (AChEI) activities 134 extracts obtained from 45 species marine sponges. Thin‐layer chromatography (TLC) and microplate assays reveal potent...