A5067326632- Rheumatoid Arthritis Research and Therapies
- Pharmacological Effects of Natural Compounds
- Healthcare and Venom Research
- Traditional Chinese Medicine Studies
- Natural product bioactivities and synthesis
- Systemic Lupus Erythematosus Research
- Cancer, Lipids, and Metabolism
- Cytokine Signaling Pathways and Interactions
- Plant-based Medicinal Research
- Ideological and Political Education
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Inflammasome and immune disorders
- Ferroptosis and cancer prognosis
- Medical Research and Treatments
- Traditional Chinese Medicine Analysis
- Toxin Mechanisms and Immunotoxins
- Lipid metabolism and disorders
- Inflammatory mediators and NSAID effects
- Natural Compounds in Disease Treatment
- Phytoestrogen effects and research
- Drug-Induced Hepatotoxicity and Protection
- Acupuncture Treatment Research Studies
- Phytochemical compounds biological activities
- Metabolomics and Mass Spectrometry Studies
Guangxi University of Chinese Medicine
2012-2025
Guangxi University
2018-2023
The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine
2021
Weatherford College
2020
MicroRNAs (miRNAs) often display different expression in many cancers and other diseases current research studies. miR-223 is upregulated rheumatoid arthritis. Also, has been demonstrated to be highly expressed pancreatic cancer gastric comparison with normal tissue. However, whether displays ovarian what its underlying functions are have remained unclear. In this study, we that miR-223-3p was Next, explored the functional role of using SKOV3 OVCAR3 cell lines. Our results suggested mimic...
Zhuang medicine visual diagnosis is one of the most characteristic diagnostic methods medicine, which has a high accuracy rate in early auxiliary some major diseases. In this paper, three cases gastric cancer patients were selected for and their signs analyzed to provide evidence clinical use assist cancer.
Gastric precancerous lesions represent a critical transitional stage, marking the final opportunity for intervention before onset of gastric cancer. Drawing parallels between toxicity and deficiency theory Zhuang medicine pathogenesis lesions, it is postulated that serves as pivotal extrinsic factor in their development, while constitutes an intrinsic underlying cause. In addressing managing emphasizes importance regulating vital energy (qi), detoxify, replenishing deficiencies, harmonizing...
The journal retracts the article titled “MicroRNA-223-3p Regulates Ovarian Cancer Cell Proliferation and Invasion by Targeting SOX11 Expression” [...]
Docetaxel is a first-line chemotherapy drug used to treat advanced prostate cancer, but patients who have it often face the challenges of resistance and side effects. Kaempferol naturally occurring flavonol; our previous studies confirmed that has excellent anti-prostate activity. To investigate cancer effects docetaxel in combination with kaempferol, we conducted experiments at cellular whole-animal level. Plate cloning assays showed kaempferol had synergistic effect inhibiting...
Long non-coding RNA (lncRNA) actin filament-associated protein 1 antisense (AFAP1-AS1) functions as a competing endogenous to regulate target genes expression by sponging microRNAs (miRs) play cancer-promoting roles in cancer stem cells. However, the regulatory mechanism of AFAP1-AS1 cervical (CC) cells is unknown. The present study aimed provide new therapeutic for clinical treatment CC.Hyaluronic acid receptor cluster differentiation 44 variant exon 6 (CD44v6)(+) CC were isolated flow...
Longzuan Tongbi Formula (LZTB) is an effective proved prescription in Zhuang medicine for treating active rheumatoid arthritis (RA). However, its ingredients, underlying targets, and pharmacological mechanism are still not clear RA. We have applied network pharmacology to study LZTB found that 8 herbs 67 compounds the involved regulation of RA-related genes; we conducted pathway analysis overlapping genes 7 participate regulations 24 pathways associated with RA 5 25 hsa05323 (rheumatoid...
Rheumatoid arthritis (RA) represents a common systemic autoimmune disease which lays chronic and persistent pain on patients. The purpose of our study is to identify novel RA-related genes biological processes/pathways. All the datasets this study, including gene expression DNA methylation RA OA samples, were obtained from free available database, i.e. Gene Expression Omnibus (GEO). We firstly identified differentially expressed (DEGs) between samples through limma package R programming...
Schisandrin B (SchB) is the highest content of biphenyl cyclooctene lignans in Schisandra chinensis. It has been reported to have a variety pharmacological effects, including anti-inflammatory, anti-oxidant, anti-cancer, heart protection, liver protection. In this study, we found that SchB can promote proliferation MC3T3-E1 subclone 14 cells. Meanwhile, regulate BMP2-SMADs signaling pathway by increasing gene and protein expression those relative biomolecules. Furthermore, raise RUNX2 SP7...
Rheumatoid arthritis (RA) is a common chronic inflammatory autoimmune disease, which can lead to joint destruction, dysfunction, finally deformity. Currently, Western medicine treats it with disease-modifying antireheumatic drugs, NSAIDs, glucocorticoid, biological agents, etc, induce adverse drug reactions. And now, as an important mean of treating RA, Zhuang has been widely used in clinics, and achieved significant efficacy.The following databases will be searched for relevant information...
To evaluate the clinical therapeutic effects and safety on rheumatoid arthritis (RA) treated with acupuncture at points detected thermosensitive moxibustion in Zhuang medicine combined western medication.A total of 168 RA patients compliance inclusive criteria were collected randomized into an observation group a control group, 84 cases each one. In reference to updated guideline new drugs by European League Against Rheumatism (EULAR) 2013, medication scheme was formulated for oral...
Systemic lupus erythematosus (SLE), known as lupus, is a chronic autoimmune disease and there no cure for SLE. The western medication can improve syndromes to some extent; however, severe adverse drug reactions appear at the same time. Recently, it confirmed that Chinese medicine also have an excellent clinical efficacy on SLE.The following databases will be searched relevant information before July 2020: PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge...
A lot of attention has been given to premature ovarian insufficiency (POI) as it poses considerable health risks women. It is characterized by oligomenorrhea, amenorrhea, infertility, autoimmune disorders, and ischemic heart disease, with increased mortality. Previous research indicates that auricular acupuncture proven effective in treating POI clinical practice. However, systematic review not carried out. Therefore, this study aims at evaluating the curative effect safety treatment for...