A5101616368- Breast Cancer Treatment Studies
- Thyroid and Parathyroid Surgery
- Thyroid Cancer Diagnosis and Treatment
- Breast Lesions and Carcinomas
- Head and Neck Anomalies
- Extracellular vesicles in disease
- Voice and Speech Disorders
- HER2/EGFR in Cancer Research
- Breast Implant and Reconstruction
- Thyroid Disorders and Treatments
- Fungal Biology and Applications
- Cancer Risks and Factors
- Ferroptosis and cancer prognosis
- MicroRNA in disease regulation
- BRCA gene mutations in cancer
- Airway Management and Intubation Techniques
- Nanoplatforms for cancer theranostics
- Cancer Genomics and Diagnostics
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cancer Cells and Metastasis
- Advanced Breast Cancer Therapies
- Immune Response and Inflammation
- Radiomics and Machine Learning in Medical Imaging
- Lymphatic System and Diseases
- Bone health and osteoporosis research
Seoul National University
2019-2025
Seoul National University Hospital
2019-2025
Asan Medical Center
1996-2024
University of Ulsan
1996-2024
Ulsan College
1998-2024
New Generation University College
2023-2024
National University College
2024
Memorial Sloan Kettering Cancer Center
2024
Biomedical Research Institute
2023
Korea University Medical Center
2017-2021
The metabolic syndrome (MS) is associated with increased life-time risk for atherosclerotic cardiovascular disease. While some reports suggest that MS and/or insulin resistance low serum free T4 (FT4) level in euthyroid subjects, this remains a controversial issue.To clarify the association of FT4 presence and its components healthy subjects.For 44,196 subjects (including 25,147 males) not taking thyroid hormone or antithyroid-drug without liver renal disease who participated routine health...
Abstract Background The surgical outcomes of a single surgeon's initial cases transoral robotic thyroidectomy (TORT) were compared with the bilateral axillo‐breast approach (BABA) thyroidectomy. Methods medical reports retrospectively reviewed. BABA thyroidectomies performed between 2008 and 2009, TORTs 2012 2016. Results Each group comprised 50 patients. Operative time for total was shorter, pain scores lower, hospital stays shorter in TORT than group. There no significant differences...
Advances in chemotherapeutic and targeted agents have increased pathologic complete response (pCR) rates after neoadjuvant systemic therapy (NST). Vacuum-assisted biopsy (VAB) has been suggested to accurately evaluate pCR. This study aims confirm the non-inferiority of 5-year disease-free survival patients who omitted breast surgery when predicted a pCR based on magnetic resonance imaging (MRI) VAB NST, compared with had undergone previous studies.
To overcome increasing bacterial resistance to conventional antibiotics, many antimicrobial peptides (AMPs) derived from host defense proteins have been developed. However, there are considerable obstacles their application systemic infections because of low bioavailability. In the present study, we developed an AMP Romo1 (AMPR-11) that exhibits a broad spectrum activity. AMPR-11 showed remarkable efficacy against sepsis-causing bacteria, including multidrug-resistant strains, with toxicity...
Background: Various approaches for thyroid surgery became possible with the use of robotic systems. Transoral thyroidectomy (TORT) is one newest and draws attention because its cosmetic excellence. In this study, we compared surgical outcomes TORT conventional open (OT). Methods: We retrospectively reviewed medical records consecutive patients who underwent or OT carcinoma from April 2016 to March 2017. Results: The study included 205 (n = 100) 105). Mean tumor size was 0.9 cm in both...
Abstract Background This study aimed to investigate the contralateral breast cancer (CBC) recurrence rate in Korean patients according their BRCA1/2 germline mutation status, focusing particularly on CBC risk negative ( BRCAx ) patients. Methods We conducted a retrospective 13,107 primary The were divided into high-risk and low-risk groups for hereditary based National Health Insurance Service’s eligibility criteria testing. group was further categorized BRCA , not tested . evaluated overall...
Standalone artificial intelligence (AI) could detect contralateral breast cancers in patients treated with unilateral mastectomy, showing higher cancer detection rates and sensitivity than radiologists without AI assistance.
Importance Patients with sporadic breast cancer have comparable prognoses after undergoing either breast-conserving treatment (BCT) or mastectomy. However, there are limited and inconsistent data on the assessment of oncologic outcomes between BCT mastectomy in patients pathogenic variants BRCA1 BRCA2 . Objective To investigate recurrence survival variants. Design, Setting, Participants This retrospective multicenter cohort study analyzed from 13 institutions South Korea primary who...
Objectives/Hypothesis Obesity is an increasing health concern worldwide. It has been associated with perioperative complications that could affect patient outcomes. Our aim was to compare surgical outcomes in obese and nonobese patients after transoral robotic thyroid (TORT) surgery. Study Design Retrospective cohort study. Methods A total of 304 consecutive who underwent TORT between January 2012 December 2017 were included the Patients divided into two groups according their body mass...
Abstract Background Despite stage IV categorization, survival outcomes for breast cancer patients who experience contralateral axillary lymph node metastasis (CAM) remain uncertain. This study aimed to investigate the clinical with metachronous CAM provide insights into its prognosis and treatment recommendations. Methods retrospectively reviewed medical records of underwent curative surgery experienced as first site distant (DM) during follow-up period between January 2001 April 2023....
Abstract Background We evaluated the outcomes of patients with papillary thyroid carcinoma (PTC) who underwent transoral robotic thyroidectomy (TORT). Methods retrospectively analyzed perioperative 200 (170 women and 30 men) PTC TORT at a single center between March 2016 February 2018. Results There were 182 13 cases lobectomy total thyroidectomy, respectively, corresponding mean operative times 200.6 ± 31.2 265.7 63.0 minutes. On average, 5.6 3.45 lymph nodes retrieved per patient. 12...
Metabolic syndrome plays a potential role in the etiology of prostate cancer and is associated with increase prostatic growth rate patients benign hyperplasia. However, influence metabolic on prostate-specific antigen (PSA) level remains unclear.Data were obtained from 23,601 men ages 40 years or older without history who underwent general health screening tests between 2006 2007 at Asan Medical Center. The criteria for consistent those defined by NCEP-ATPIII-AHA/NHLBI statement....
The incidence of pediatric thyroid cancer is relatively low compared to the disease in adults. This study aims present data our institution on patients, with particular emphasis risk factors recurrence together treatment outcomes.Between January 2000 and July 2018, patients <20 years who were diagnosed carcinoma primarily treated surgery at a major large-volume tertiary medical center specializing enrolled. A total 83 eligible for this study.The majority studied girls adolescents (age ≥13...
Abstract Axillary nodal status is one of the most important prognostic factors in breast cancer. The lymph node ratio (LNR) has been suggested as an independent factor because number dissected and involved nodes might differ across institutions. Neoadjuvant chemotherapy (NAC) preferred treatment method for reducing tumor mass axillary area. However, NAC can reduce total excised compared with upfront surgery. Therefore, emerging question whether LNR following accurately predict prognosis. We...
Abstract Objective This study aimed to determine whether sentinel lymph node biopsy (SLNB) alone could afford oncological outcomes comparable with axillary dissection (ALND) in patients early breast cancer without palpable lymphadenopathy who underwent total mastectomy (TM) and were SLN-positive. Methods analyzed clinical data of 6747 TM between 2014 2018 two tertiary hospitals Korea. Overall, 643 stage T1-3 N0 did not receive neoadjuvant therapy had one metastatic SLNs at the time surgery...