A5101796921- Biological Stains and Phytochemicals
- Plant-Derived Bioactive Compounds
- Healthcare and Venom Research
- Cancer Genomics and Diagnostics
- Traditional Chinese Medicine Studies
- Ferroelectric and Piezoelectric Materials
- Microwave Dielectric Ceramics Synthesis
- Dielectric materials and actuators
- Cardiac Ischemia and Reperfusion
- Inflammatory mediators and NSAID effects
- Ferroptosis and cancer prognosis
- Nitric Oxide and Endothelin Effects
- Radiomics and Machine Learning in Medical Imaging
- Antibiotics Pharmacokinetics and Efficacy
- RNA Interference and Gene Delivery
- Melanoma and MAPK Pathways
- Polysaccharides and Plant Cell Walls
- Bioinformatics and Genomic Networks
- Fungal Biology and Applications
- Poisoning and overdose treatments
- Lung Cancer Treatments and Mutations
- Synthesis and bioactivity of alkaloids
- Advanced biosensing and bioanalysis techniques
- Bioactive Compounds and Antitumor Agents
- Acoustic Wave Resonator Technologies
Korea Institute of Science and Technology
2024
Jeuk (South Korea)
2021-2022
Pusan National University
2019-2020
Semyung University
2017-2019
Inha University
2013-2015
Ajou University
1999-2004
Ewha Womans University
1999
Seoul National University
1988-1991
Prognostic genes or gene signatures have been widely used to predict patient survival and aid in making decisions pertaining therapeutic actions. Although some web-based analysis tools developed, they several limitations.Taking these limitations into account, we developed ESurv (Easy, Effective, Excellent Survival tool), a tool that can perform advanced analyses using user-derived data from The Cancer Genome Atlas (TCGA). Users conduct univariate grouped variable selections multiomics...
Understanding cancer heterogeneity is essential to finding diverse genetic mutations in metastatic cancers.Thus, it critical isolate all types of CTCs identify accurate information from patients.Moreover, full automation robustly capturing the spectrum an urgent need for CTC diagnosis be routine clinical practice.Methods: Here we report capture heterogeneous populations using fully automated, negative depletion-based continuous centrifugal microfluidics (CCM).Results: The CCM system...
Nanograined PbTiO 3 ( PT ) thick films were deposited on Si , yttria‐stabilized zirconia YSZ ), and Ni substrates using an aerosol deposition AD method at room temperature. The each different substrate annealed 500°C 700°C for 1 h to increase the crystallinity. stresses in film modulated by controlling difference coefficient of thermal expansion CTE between during annealing process. morphology was examined from polycrystalline dense structure (thickness ~8 μm), changes crystallographic...
Abstract Necroptosis, a cell death mechanism with the characteristics of both apoptosis and necrosis, is proposed as promising therapeutic approach for cancer therapy. Induction necroptosis therapy may be possible through regulation expression key factor gene receptor‐interacting protein kinase‐3 (RIPK3) via in vitro transcription (IVT) mRNA delivery. However, susceptible to degradation has low delivery efficiency, which highlights requirement proper vehicle intracellular Therefore, new...
Cutaneous melanoma is the most common cause of skin cancer-related deaths worldwide. There an urgent need to identify prognostic biomarkers facilitate decision-making for treatment metastatic cutaneous melanoma. Gene expression microarrays and RNA-seq technology have recently improved or changed current therapeutic strategies several cancers. However, according staging system, prognosis almost entirely dependent on clinicopathological features. To novel biomarkers, we investigated gene...
The purpose of this thesis is to compare and analyze outcomes case studies controlled about Hwangryunhaedok-tang (HHT) pharmacopuncture in clinical studies. Based on these reporting effects by using HHT pharmacopuncture, we object deduct the comparative review applying disorders limitedly. And conclusionally, review, aim make fine evidence treating specific diseases.
<sec> <title>BACKGROUND</title> Prognostic genes or gene signatures have been widely used to predict patient survival and aid in making decisions pertaining therapeutic actions. Although some web-based analysis tools developed, they several limitations. </sec> <title>OBJECTIVE</title> Taking these limitations into account, we developed ESurv (Easy, Effective, Excellent Survival tool), a tool that can perform advanced analyses using user-derived data from The Cancer Genome Atlas (TCGA). Users...
Abstract Background: EGFR-TKI is an established first-line therapy for NSCLC with activating EGFR mutations. Osimertinib, third-generation TKI, was investigated as a first-in-class drug, but lazertinib(YH25448) also reported outstanding drug which had similar efficacy osimertinib. Nevertheless, acquired resistance inevitably developed by EGFR-TKIs in clinic. Even though C797S mutation has been identified major resistant mechanism, the remaining mechanisms to these TKIs are largely unknown....