A5100625296- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- Endometrial and Cervical Cancer Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Medical Imaging Techniques and Applications
- Autophagy in Disease and Therapy
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- AI in cancer detection
- Circular RNAs in diseases
- Sirtuins and Resveratrol in Medicine
- Cancer-related gene regulation
- Sarcoma Diagnosis and Treatment
- Anesthesia and Sedative Agents
- Pregnancy and preeclampsia studies
- Nutritional Studies and Diet
- Birth, Development, and Health
- Lymphoma Diagnosis and Treatment
- Cancer Risks and Factors
- Epigenetics and DNA Methylation
- Genomics, phytochemicals, and oxidative stress
- Lung Cancer Treatments and Mutations
- Colorectal Cancer Surgical Treatments
- FOXO transcription factor regulation
- Intestinal and Peritoneal Adhesions
Liaoning Cancer Hospital & Institute
2018-2024
Dalian University of Technology
2023-2024
Hainan Medical University
2023
First Affiliated Hospital of Bengbu Medical College
2023
Inner Mongolia People's Hospital
2022
Second Affiliated Hospital of Xi'an Jiaotong University
2022
China Medical University
2018-2021
North China University of Science and Technology Affiliated Hospital
2020-2021
Union Hospital
2021
Jilin University
2021
Background Lymph node metastasis (LNM) is the principal risk factor for poor outcomes in early‐stage cervical cancer. Radiomics may offer a noninvasive way predicting stage of LNM. Purpose To evaluate radiomic signature LN involvement based on sagittal T 1 contrast‐enhanced (CE) and 2 MRI sequences. Study Type Retrospective. Population In all, 143 patients were randomly divided into two primary validation cohorts with 100 cohort 43 cohort. Field Strength/Sequence CE sequences at 3T....
Objectives: To develop a radiomic model based on multiparametric magnetic resonance imaging (MRI) for predicting treatment response prior to commencing concurrent chemotherapy and radiation therapy (CCRT) locally advanced cervical cancer. Materials Methods: The retrospective study enrolled 120 patients (allocated training or test set) with cancer who underwent CCRT between December 2014 June 2017. All MRI 9 sequences before again at the end of fourth week treatment. Responses were evaluated...
The contribution of autophagy to cancer therapy resistance remains complex, mainly owing the discrepancy mechanisms in different therapy. However, potential autophagy-mediated icotinib have yet be elucidated.The effect was examined using a series vitro and vivo assays. results above were further verified biopsy specimens lung patients before after or gefitinib treatment.Icotinib increased ATG3, ATG5, ATG7 expression, but without affecting Beclin-1, VPS34 ATBG14 levels icotinib-resistant...
Although MIR516A has been reported to be downregulated and act as a tumor suppressor in multiple cancers, its expression potential contribution human bladder cancer (BC) remain unexplored. Unexpectedly, we showed here that was markedly upregulated BC tissues cell lines, while inhibition of attenuated monolayer growth vitro xenograft vivo, accompanied with increased PHLPP2. Further studies able directly bind the 3′-untranslated region PHLPP2 mRNA, which essential for attenuating expression....
To non-invasively evaluate the Ki-67 level in digital breast tomosynthesis (DBT) images of cancer (BC) patients based on subregional radiomics.A total 266 who underwent DBT scans were consecutively enrolled at two centers, between September 2017 and 2021. The whole tumor region was partitioned into various intratumoral subregions, individual- population-level clustering. Handcrafted radiomics deep learning-based features extracted from subregions region, selected by least absolute shrinkage...
Ewing's sarcoma (ES) is one of the most prevalent malignant bone tumors worldwide. However, molecular mechanisms genes and signaling pathways ES are still not well sufficiently comprehended. To identify candidate involved in development progression ES, study screened for key biological related to using bioinformatics methods.The GSE45544 GSE17618 microarray datasets were downloaded from Gene Expression Omnibus (GEO) database. Differentially expressed (DEGs) identified, functional enrichment...
Background: The hemodynamic variations of cardiac and cerebral blood monitoring during pneumoperitoneum head-down tilt position in general anesthetized elderly patients remain unresolved. We evaluated the time course tissue oxygen saturation (SctO2) output (CO) investigated how changes values surgery would affect perfusion patients.Methods: In this prospective observational study 47 (≥65 years old, American Society Anesthesiologists Physical status I to III) undergoing laparoscopic...
Objective: The present study aimed to explore the function of sirtuin 2 (SIRT2) on cell proliferation, apoptosis, rat sarcoma virus (RAS)/ extracellular signal-regulated kinase (ERK) pathway in endometrial cancer (EC). Methods: SIRT2 expression human EC lines and (uterine) epithelial (HEEC) line was assessed by reverse transcription-quantitative polymerase chain reaction (RT-qPCR) western blot. knock-down control plasmids were transfected into HEC1A cells, respectively; overexpression...
Intestinal obstruction is one of the most common diseases in abdominal surgery, and its prevention treatment a clinical difficulty. Although surgical operation can solve symptoms obstruction, there are many postoperative complications, it easy to develop re-obstruction due adhesion. The internal fixation small intestine with catheter provides new idea for adhesive bowel obstruction. use transanal ileus possibility direct intestinal anastomosis after resection malignant left hemicolon reduce...
Objective To evaluate the feasibility of ETView visual endotracheal intubation in elderly patients with a potentially difficult airway under general anesthesia. Methods A total 80 scheduled for elective surgery, at least three characteristics indicative an increased risk tracheal and aged 65-86 years American Society Anesthesiologists (ASA) grade Ⅱ or Ⅲ, were selected randomly assigned into 2 groups: control group (Group C) E) (n=40 each). After induction propofol 0.5-1.5 mg/kg,...
Neoadjuvant chemotherapy (NAC) is the standard treatment for breast cancer patients. Patients achieving complete pathological response (pCR) after NAC usually have a good prognosis. However, automatic pCR prediction has been challenging problem due to lacking well annotations in 3D MRI. Thus far, unifying different annotation information predict tumor's early not systematically addressed. This paper proposes weakly and semi-supervised joint learning method that integrates attentional...