A5069637655- Advanced Neuroimaging Techniques and Applications
- MRI in cancer diagnosis
- Advanced MRI Techniques and Applications
- Advanced Radiotherapy Techniques
- Renal and Vascular Pathologies
- Hepatocellular Carcinoma Treatment and Prognosis
- Acute Ischemic Stroke Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Effects of Radiation Exposure
- Medical Imaging Techniques and Applications
- Dialysis and Renal Disease Management
- Salivary Gland Tumors Diagnosis and Treatment
- Lipid metabolism and disorders
- Botulinum Toxin and Related Neurological Disorders
- Inflammatory Bowel Disease
- Nerve injury and regeneration
- Cannabis and Cannabinoid Research
- NF-κB Signaling Pathways
- Lung Cancer Research Studies
- Barrier Structure and Function Studies
- Neurosurgical Procedures and Complications
- Chronic Kidney Disease and Diabetes
- Neuroscience and Neuropharmacology Research
- Dementia and Cognitive Impairment Research
- Folate and B Vitamins Research
Taipei Medical University
2013-2024
Sixth Affiliated Hospital of Sun Yat-sen University
2018
Sun Yat-sen University
2018
Taipei Medical University Hospital
2016-2018
University of Pennsylvania
2013-2018
National Yang Ming University Hospital
2016
National Yang Ming Chiao Tung University
2016
Tri-Service General Hospital
2008-2013
National Taiwan University
2004-2013
Kaohsiung Medical University
2013
Purpose To investigate the pathophysiologic effects of chronic kidney disease (CKD) on brain function in children with CKD by correlating cerebral blood flow (CBF) clinical and behavioral indexes. Materials Methods In this prospective study, 73 pediatric patients (mean age, 15.80 years ± 3.63; range, 9–25 years) 57 control subjects 15.65 3.76; were recruited. CBF measurements acquired an MRI arterial spin labeling scheme. Neurocognitive performed traditional computerized neurocognitive...
To compare the image distortion and quantification variation in parotid gland apparent diffusion coefficients (ADCs) on periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) versus echo-planar diffusion-weighted (DW) magnetic resonance (MR) images to investigate relationship between ADC fat content.This prospective study was approved by a local institutional review board. Written informed consent obtained from all 33 enrolled healthy volunteers (15 men, 18...
Background: Although the ABC/2 formula has been widely used to estimate volume of intracerebral hematoma (ICH), tends overestimate volume. The volume-related imprecision not documented quantitatively. Purpose: To investigate volume-dependent overestimation by comparing it with computer-assisted volumetric analysis (CAVA). Material and Methods: Forty patients who had suffered spontaneous ICH undergone non-enhanced brain computed tomography scans were enrolled in this study. was estimated...
Utilizing a classic stroke model in rodents, middle cerebral artery occlusion (MCAo), we describe novel neuroregenerative approach using the repeated intranasal administration of cocaine- and amphetamine-regulated transcript (CART) peptide starting from day 3 poststroke for enhancing functional recovery injured brain. Adult rats were separated into two groups with similar infarction sizes, measured by magnetic resonance imaging on 2 after MCAo, treated CART or vehicle. The treatment...
Background and Purpose— Brain enhancement on contrast-enhanced T1-weighted imaging (CET1-WI) after ischemic stroke is generally accepted as an indicator of the blood–brain barrier disruption. However, this phenomenon usually starts to become visible at subacute phase. The purpose study was evaluate time-course profiles K trans , cerebral blood volume ( v p ), CET1-WI with early detection changes maps their role for prediction subsequent hemorrhagic transformation in acute middle arterial...
Purpose To investigate quantitatively the topographic perfusion characteristics of adenohypophysis by using dynamic contrast material–enhanced magnetic resonance (MR) imaging in a subgroup patients with idiopathic growth hormone deficiency (IGHD) and normal-appearing pituitary morphology on MR images. Materials Methods This HIPAA-compliant, prospective study was approved an institutional review board, informed consent obtained for all patients. Twenty-five (mean age, 10.6 years ± 3.3...
Purpose To investigate the effects of 3,4-methylenedioxymethamphetamine (MDMA, commonly known as "ecstasy") on alterations brain metabolites and anatomic tissue integrity related to function basal ganglia–thalamocortical circuit by using proton magnetic resonance (MR) spectroscopy diffusion-tensor MR imaging. Materials Methods This study was approved a local institutional review board, written informed consent obtained from all subjects. Thirty-one long-term (>1 year) MDMA users 33 healthy...
Chronic kidney disease is strongly linked to neurocognitive deficits in adults and children, but the pathophysiologic processes leading these remain poorly understood. The NiCK study (Neurocognitive Assessment Magnetic Resonance Imaging Analysis of Children Young Adults with Kidney Disease) seeks address critical gaps our understanding biological basis for neurologic abnormalities chronic disease. In this report, we describe objectives, design, methods study.The Study a cross-sectional...
Evaluation of acute white matter injuries caused by carbon monoxide (CO) poisoning can be limited conventional magnetic resonance (MR) imaging. We aim to evaluate the feasibility diffusion kurtosis imaging (DKI) for early detection alterations in patients with CO intoxication. A total 30 subjects including 15 and age- sex-matched healthy volunteers were enrolled this study. MR examinations performed on a 3T scanner within 8 days after DKI data acquired derive axial, radial, mean kurtosis, as...
A 27-year-old man had been diagnosed with ataxia-telangiectasia at age 13 years. He ocular telangiectasia and motor ataxia, incoordination of head eyes in lateral gaze. Laboratory data revealed deficiency immunoglobulin elevated α-fetoprotein. MRI demonstrated cerebellar atrophy cerebral microbleeds1 (figure 1); the dentate nuclei deficient iron signals, which otherwise should be visible as hypointensities susceptibility-weighted imaging 2). Iron depletion is a novel finding could explained...
The aim of this study was to evaluate the interobserver variability in diagnosing inflammatory bowel disease (IBD)-associated neoplasia among practicing pathologists from China using telepathology, a practice remote diagnostic consultation increasingly used nationally and internationally, its comparison with interpretation subspecialized gastrointestinal (GI) United States (US). Eight GI US 4 an interest pathology participated study. A total 50 colonic biopsies patients clinical history IBD...