A5075659057- Dementia and Cognitive Impairment Research
- Action Observation and Synchronization
- Attention Deficit Hyperactivity Disorder
- Functional Brain Connectivity Studies
- Stroke Rehabilitation and Recovery
- Olfactory and Sensory Function Studies
- Autism Spectrum Disorder Research
- Neurobiology of Language and Bilingualism
- Face Recognition and Perception
- Schizophrenia research and treatment
- Cognitive Functions and Memory
- Mental Health Research Topics
- Psychosomatic Disorders and Their Treatments
- Advanced Chemical Sensor Technologies
- Digital Mental Health Interventions
- Allergic Rhinitis and Sensitization
- Aging, Elder Care, and Social Issues
- Evolutionary Psychology and Human Behavior
- Hearing Impairment and Communication
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Language, Metaphor, and Cognition
- Multisensory perception and integration
- Child and Adolescent Psychosocial and Emotional Development
- Child and Animal Learning Development
- Neural and Behavioral Psychology Studies
Université Côte d'Azur
2016-2025
Cognition Behaviour Technology
2016-2025
Association France Alzheimer
2018-2025
Observatoire de la Côte d’Azur
2020-2024
Centre Hospitalier Universitaire de Nice
2016-2024
Centre Pompidou
2016-2022
Institut national de recherche en informatique et en automatique
2017-2021
Institute of Psychiatry and Neurology
2021
Institut de Biologie Valrose
2019-2020
Research Centre Inria Sophia Antipolis - Méditerranée
2018
To evaluate the interest of using automatic speech analyses for assessment mild cognitive impairment (MCI) and early-stage Alzheimer's disease (AD).Healthy elderly control (HC) subjects patients with MCI or AD were recorded while performing several short vocal tasks. The voice recordings processed, first markers extracted signal processing techniques. Second, tested to assess their "power" distinguish among HC, MCI, AD. second step included training classifiers detecting AD, machine learning...
Abstract Background: Apathy is a very common behavioural and psychological symptom across brain disorders. In the last decade, there have been considerable advances in research on apathy motivation. It thus important to revise diagnostic criteria published 2009. The main objectives were to: a) definition of apathy; b) update list dimensions; c) operationalise criteria; d) suggest appropriate assessment tools including new technologies. Methods: expert panel (N = 23) included researchers...
Processing biological motion is fundamental for everyday life activities, such as social interaction, motor learning and nonverbal communication. The ability to detect the nature of a pattern has been investigated by means point-light displays (PLD), sets moving light points reproducing human kinematics, easily recognizable meaningful once in motion. Although PLD are rudimentary, brain can decipher their content including intentions. Neuroimaging studies suggest that inferring meaning...
Virtual Reality (VR) has emerged as a promising tool in many domains of therapy and rehabilitation, recently attracted the attention researchers clinicians working with elderly people MCI, Alzheimer’s disease related disorders. Here we present study testing feasibility using highly realistic image-based rendered VR patients MCI dementia. We designed an attentional task to train selective sustained attention, tested paper version this single-session within-subjects design. Results showed that...
Alzheimer’s disease and other related disorders (ADRD) represent a major challenge for health care systems within the aging population. It is therefore important to develop better instruments assess severity progression, as well improve its treatment, stimulation, rehabilitation. This underlying idea development of Serious Games (SG). These are digital applications specially adapted purposes than entertaining; such rehabilitation, training education. Recently, there has been an increase...
Recently there has been a growing interest in employing serious games (SGs) for the assessment and rehabilitation of elderly people with mild cognitive impairment (MCI), Alzheimer's disease (AD), related disorders. In present study we examined acceptability 'Kitchen cooking' - SG developed context EU project VERVE (http://www.verveconsortium.eu/) these populations. this game cooking plot is employed to assess stimulate executive functions (such as planning abilities) praxis. The installed on...
Apathy is common in neurocognitive disorders (NCD) but NCD-specific diagnostic criteria are needed.The International Society for CNS Clinical Trials Methodology Work Group convened an expert group and sought input from academia, health-care, industry, regulatory bodies. A modified Delphi methodology was followed, included extensive literature review, two surveys, meetings at international conferences, culminating a consensus meeting 2019.The final reached with more than 80% agreement on all...
Abstract Mirror neurons are increasingly recognized as a crucial substrate for many developmental processes, including imitation and social learning. Although there has been considerable progress in describing their function localization the primate adult human brain, we still know little about ontogeny. The idea that mirror result from Hebbian learning while child observes/hears his/her own actions received remarkable empirical support recent years. Here add new element to this proposal, by...
Skepticism has been expressed concerning the possibility to understand others' intentions by simply observing their movements: since a number of different may have produced particular action, motor information-it argued-might be sufficient what an agent is doing, but not her remote goal in performing that action. Here we challenge this conclusion showing absence contextual information, can inferred from body movement. Based on recent empirical findings, shall contend that: (1) translate into...
Is it possible to use highly realistic virtual reality in the elderly? A feasibility study with image-based rendering Michel Benoit,1,2 Rachid Guerchouche,3 Pierre-David Petit,1 Emmanuelle Chapoulie,3 Valeria Manera,1 Gaurav Chaurasia,3 George Drettakis,3 Philippe Robert1,4 1EA CoBTeK/IA, University of Nice Sophia Antipolis, 2Clinique de Psychiatrie, Pole des Neurosciences Cliniques, CHU Nice, 3Institut National Recherche en Informatique et Automatique, Sophia-Antipolis, 4Centre...
This study was conducted to examine interpersonal predictive coding in individuals with high-functioning autism (HFA). Healthy and HFA participants observed point-light displays of two agents (A B) performing separate actions. In the 'communicative' condition, action performed by agent B responded a communicative gesture A. 'individual' A's substituted non-communicative action. Using simultaneous masking-detection task, we demonstrate that observing enhanced visual discrimination for healthy...
The use of Serious exerGames (SeG) as enriched environments (EE), which promotes cognitive simulation with physical activity in a positive emotional context, has been proposed to represent powerful method slow down the decline due neurodegenerative diseases (ND), such Alzheimer's disease (AD). However, so far, no SeG targeting EE tested ND subjects.This study aimed at evaluating usability and short-term training effects X-Torp, an action designed for elderly subjects mild impairment (MCI)...
In the context of interacting activities requiring close-body contact such as fighting or dancing, actions one agent can be used to predict second agent. present study, we investigated whether interpersonal predictive coding extends interactive activities--such communicative interactions--in which no physical contingency is implied between movements individuals.Participants observed point-light displays two agents (A and B) performing separate actions. condition, action performed by B...
The use of Serious Games (SG) in the health domain is expanding. In field neurodegenerative disorders (ND) such as Alzheimer's disease, SG are currently employed both to support and improve assessment different functional cognitive abilities, provide alternative solutions for patients' treatment, stimulation, rehabilitation. As quite young, recommendations on people with ND still rare. 2014 we proposed some initial (Robert et al., 2014). aim present work was update them, thanks opinions...
Cognitive and behavioral symptoms are the clinical hallmarks of neurocognitive disorders. training may be offered to reduce risks cognitive decline dementia symptoms, such as apathy. Information communication technology approaches, including serious games, can useful in improving playful aspect computerized providing motivating solutions elderly patients.The objective this study was assess effectiveness employing MeMo (Memory Motivation) Web app with regard patients disorders.MeMo is a that...
Assistive technologies became pervasive and virtually present in all our life domains. They can be either an enabler or obstacle leading to social exclusion. The Fondation Médéric Alzheimer gathered international experts of dementia care, with backgrounds biomedical, human sciences, analyze how assistive address the capabilities people dementia, on basis their needs. Discussion covered unmet needs domains daily activities where provide help enabling empowering impact technology improve...
Background: Neuropsychiatric symptoms, also known as behavioral and psychological symptoms of dementia (BPSD), affect the majority patients with dementia, result in a greater cognitive functional impairment. Objective: To investigate associations between BPSD amyloid cerebral deposition measured by 18F-Florbetapir-PET quantitative uptake elderly subjects without Methods: Participants impairment [mild (MCI) or Alzheimer’s disease (AD)] healthy controls (HC) from ADNI cohort (Alzheimer Disease...
Gender distribution varies across neurodegenerative disorders, with, traditionally, a higher female frequency reported in Alzheimer's disease (AD) and male Parkinson's (PD). Conflicting results on gender are concerning dementia with Lewy bodies (DLB), usually considered as an intermediate between AD PD. The aim of the present study was to investigate differences DLB French specialized memory settings using data from national database spanning 2010 2015 compare sex ratio that AD, (PDD), Our...
Background Beyond providing cues about an agent's intention, communicative actions convey information the presence of a second agent towards whom action is directed (second-agent information). In two psychophysical studies we investigated whether perceptual system makes use this to infer when dealing with impoverished and/or noisy sensory input. Methodology/Principal Findings Participants observed point-light displays agents (A and B) performing separate actions. Communicative condition, B's...
Cognitive reappraisal (CR) is a commonly used emotion-regulation strategy that has been shown to influence affective, cognitive, and social outcomes. Although progress made in elucidating the mechanisms underlying CR, role of attention remains unclear. In present study, we investigated CR by tracking participants' gazes during presentation videos depicting people negative moods. Participants were asked attend naturally or use increase decrease their emotions while viewing videos. After each...
What makes people spontaneously adopt the perspective of others? Previous work suggested that taking can serve understanding actions others. Two studies corroborate and extend interpretation. The first study varied cues to intentionality eye gaze action, found more actor was perceived as potentially interacting with objects, stronger tendency take his perspective. second investigated how manipulations affect another reaching for an object. Eliminating by blurring actor's face did not reduce...