A5029152772- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer Mechanisms and Therapy
- Pelvic floor disorders treatments
- Caveolin-1 and cellular processes
- Kruppel-like factors research
- Appendicitis Diagnosis and Management
- Urinary Bladder and Prostate Research
- Colorectal Cancer Surgical Treatments
- Urological Disorders and Treatments
- Pancreatic and Hepatic Oncology Research
- Ureteral procedures and complications
- Cancer-related gene regulation
- Anorectal Disease Treatments and Outcomes
- Pediatric Urology and Nephrology Studies
- Abdominal Surgery and Complications
- Esophageal Cancer Research and Treatment
- Hernia repair and management
- Cardiac, Anesthesia and Surgical Outcomes
- RNA modifications and cancer
- Esophageal and GI Pathology
- Endometriosis Research and Treatment
- Urinary and Genital Oncology Studies
- Trauma Management and Diagnosis
- Aortic Disease and Treatment Approaches
- Metastasis and carcinoma case studies
Sakai Municipal Hospital
2013-2025
Teikyo University Chiba Medical Center
2022-2025
Sapporo Medical University
2017-2020
Nagoya University
1999-2019
Ebara (Japan)
2018-2019
Chiba University
2005-2017
Virginia Commonwealth University
2015-2017
Toho University
2014
The University of Texas MD Anderson Cancer Center
2014
Hokkaido University
2008-2014
Exosomes play important roles in cancer progression. Although its contents (e.g., proteins and microRNAs) have been focused on research, particularly as potential diagnostic markers, the exosome behavior methods for quantification remain unclear. In present study, we analyzed tumor-derived assessed of exosomes patient plasma a biomarker esophageal squamous cell carcinoma (ESCC). A CD63-GFP expressing human ESCC line (TE2-CD63-GFP) was made by transfection, mouse subcutaneous tumor models...
Aims: To investigate the prevalence and characteristics of nocturnal enuresis (NE) to examine overactive bladder (OAB) symptoms in primary schoolchildren. Methods: After conducting an anonymous questionnaire survey about voiding habits bowel schoolchildren, a total 6917 schoolchildren belonging 11 schools were randomly enrolled survey. According International Continence Society, we defined NE as any involuntary loss urine during sleep, occurring more frequently than once per month. Children...
No AccessJournal of UrologyClinical Urology: Original Article1 Jan 1996Collagen Injection for Intrinsic Sphincteric Deficiency in Men Sherif R. Aboseif, Helen E. O'Connell, Akihiro Usui, and Edward J. McGuire AboseifSherif Aboseif , O'ConnellHelen O'Connell UsuiAkihiro Usui McGuireEdward View All Author Informationhttps://doi.org/10.1016/S0022-5347(01)66525-XAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract...
No AccessJournal of UrologyPEDIATRIC UROLOGY1 Jan 2004The Micturition Habits and Prevalence Daytime Urinary Incontinence in Japanese Primary School Children MITSURU KAJIWARA, KATSUMI INOUE, AKIHIRO USUI, MAKOTO KURIHARA, TSUGURU USUI KAJIWARAMITSURU KAJIWARA , INOUEKATSUMI INOUE USUIAKIHIRO KURIHARAMAKOTO KURIHARA USUITSUGURU View All Author Informationhttps://doi.org/10.1097/01.ju.0000101907.87169.06AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints...
More than 60% of patients who are diagnosed with epithelial ovarian cancer (EOC) present extensive peritoneal carcinomatosis. EOC cells typically disseminate by shedding into the fluid in which they survive as multicellular aggregates and then implant onto surfaces. However, mechanism that facilitates aggregation implantation is poorly understood. The cell adhesion molecule P-cadherin has been reported to be induced during early progression promote tumor migration. In this study, not only...
Abstract OBJECTIVES To evaluate the background trends and surgical outcomes for more than 10 000 patients with acute type A dissection in Japan a recent 8-year period. METHODS Data on replacement of ascending aorta and/or aortic arch were collected from Cardiovascular Surgery Database 2008 to 2015. Linear-by-linear association tests or Cuzick’s test trend was used group over time. The results calculated hemiarch replacement. multivariable logistic regression model calculate risk-adjusted...
// Tadashi Ogawa 1, 2 , Yoshihiko Hirohashi 1 Aiko Murai Toshihiko Nishidate Kenji Okita Liming Wang Yuzuru Ikehara 3 Tetsuta Satoyoshi Akihiro Usui Terufumi Kubo Munehide Nakastugawa Takayuki Kanaseki Tomohide Tsukahara Goro Kutomi Tomohisa Furuhata Koichi Hirata Noriyuki Sato Toru Mizuguchi Ichiro Takemasa and Torigoe Department of Pathology, Sapporo Medical University School Medicine, Chuo-Ku, 060-8556, Japan Surgery, The Molecular Medicine Team, Research Center for Glycoscience, National...
Abstract Background Accurate identification of tumor sites during laparoscopic colorectal surgery helps to optimize oncological clearance. We aimed assess the timing local injection preoperatively and clarify usefulness limitation site marking using indocyanine green (ICG) fluorescence imaging. Methods Consecutive patients who underwent primary cancer from September 2017 January 2019 were included. Preoperatively, lower endoscopy was used inject ICG solution into submucosal layer near tumor....
We evaluated our recent experience with transurethral collagen therapy in women.A series of 44 women video urodynamic evidence intrinsic sphincter deficiency were treated using local anesthesia. Median patient age was 72 years (range 41 to 94). Mean duration incontinence months. Incontinence grade 3 42 patients. abdominal leak point pressure before treatment 56 cm. water. Patient response by the change number pads required effect significant improvement.Median used 5 pretreatment 12) and...
We tested a new therapeutic modality for head and neck esophageal cancers, combination of direct intratumoral (i.t.) administration dendritic cells (DCs) radiation therapy (RT) in mouse squamous cell carcinoma (SCC). also evaluated the functions gp96, which can enhance systemic antitumor activity, mechanism abscopal effect. Mouse SCC (1 x 10(5)), SCCVII, were inoculated into left femur C3H/He mice subcutaneously, similarly chest subcutaneous tissue. Only tumor was exposed to 4 or 10 Gy...
Abstract BACKGROUND: The expression of Fra‐1 (Fos related antigen 1) involves tumor progression and invasion, its gene ablation could suppress the invasive phenotypes human cells. authors investigated significance in esophageal squamous cell carcinoma (ESCC) studied effect down‐regulation on proliferation, motility, invasion. METHODS: Surgical specimens from 164 patients with ESCC were evaluated. primary along metastatic lymph nodes was compared among various clinicopathological...
The low anterior resection syndrome (LARS) score is a patient-reported outcome measure to evaluate the severity of bowel dysfunction after rectal cancer surgery by scoring major symptoms LARS. aim this study was translate English version LARS into Japanese and investigate validity reliability score.The translated in following current international recommendations. A total 149 patients completed questionnaire were also asked single question assessing impact function on quality life (QoL). 136...
Postoperative changes in body composition (BC) have not been clearly defined. The aim of this study was to clarify the impact postoperative comprehensive BC on long-term prognosis gastric cancer (GC) patients. A total 366 GC patients who underwent radical gastrectomy were included. skeletal muscle volume, fat and density investigated at six months postoperatively using computed tomography evaluated their association with survival. Patients decreased increased had a poor prognosis,...
<title>Abstract</title> Purpose Surgical fixation of traumatic multiple rib fractures is becoming more common; video-assisted thoracoscopic surgery (VATS) reportedly useful in such cases. Therefore, we aimed to explore the feasibility and effectiveness VATS for surgical stabilization (SSRF). Methods We conducted a single-center, medical record-based retrospective cohort study including 52 patients with who underwent SSRF or without VATS. All were admitted our hospital between January 2017...
Tricuspid regurgitation (TR) remains a significant risk factor affecting the survival of patients with hypoplastic left heart syndrome (HLHS). We performed this study to investigate differences in clinical course based on timing development TR and effects tricuspid valve surgery (TVS). One hundred five classic HLHS underwent staged operations from May 1991 July 2010. Forty-four (41.9%) exhibited moderate or greater during follow-up. defined early group (30 patients, around first palliative...
Objective: To determine whether Aquacel Ag Hydrofiber dressings containing ionic silver are superior to film for preventing superficial surgical site infections (SSI) in patients undergoing elective gastrointestinal surgery. Background: Multiple clinical trials have assessed the effectiveness of silver-containing wound dressings; however, systematic reviews failed find any advantages these and concluded that there was insufficient evidence indicate they prevented infections. This study aimed...
The antitumor mechanism of histone deacetylase (HDAC) inhibitors differs from conventional agents. HDAC may be effective as novel therapeutic agents for esophageal squamous cell carcinoma (ESCC). This study describes the antiproliferative activity CHAP31, a inhibitor. Furthermore, molecular CHAP31-induced apoptosis was investigated in ESCC.The CHAP31 tested cancer lines (T.Tn and TE2), potent observed vitro vivo. In addition, induced cells. Next, mechanisms were examined using quantitative...
Abstract Background Ampullary adenomas are premalignant lesions. However, biliary obstruction causing jaundice is rare. Duodenal intussusception secondary to an ampullary adenoma rarely occurs because of the fixed position duodenum in retroperitoneum. Herein, we have described a rare case with caused by duodenal intussusception. Case presentation A 40-year-old woman presenting vomiting and yellowish discoloration skin was admitted another hospital. The patient had experienced recurrent...