A5100436577- Plant Virus Research Studies
- Plant Molecular Biology Research
- Chromosomal and Genetic Variations
- RNA modifications and cancer
- Insect Resistance and Genetics
- Genomic variations and chromosomal abnormalities
- Plant-Microbe Interactions and Immunity
- Plant tissue culture and regeneration
- Insect-Plant Interactions and Control
- Congenital heart defects research
- Pineapple and bromelain studies
- Legume Nitrogen Fixing Symbiosis
- Prenatal Screening and Diagnostics
- Photosynthetic Processes and Mechanisms
- Viral Infectious Diseases and Gene Expression in Insects
- Insect symbiosis and bacterial influences
- RNA Interference and Gene Delivery
- Plant Stress Responses and Tolerance
- Plant Gene Expression Analysis
- Virus-based gene therapy research
- Metabolism and Genetic Disorders
- Phytochemistry and Biological Activities
- Redox biology and oxidative stress
- Molecular Biology Techniques and Applications
- Enzyme Catalysis and Immobilization
Sichuan University
2022-2025
Wuhan University
2025
Hong Kong Jockey Club
2025
Chinese University of Hong Kong
2025
Anhui Medical University
2021-2025
Anhui University
2025
Fujian Agriculture and Forestry University
2018-2024
Shanghai Jiao Tong University
2016-2024
South China Agricultural University
2013-2024
Peking University
2024
ABSTRACT Background The combined effects of some modifiable lifestyle factors on incident inflammatory bowel disease (IBD) are uncertain. Aims To evaluate the association between healthy behaviours and IBD incidence. Methods This population‐based prospective cohort study used data from UK Biobank. We included 105,715 participants aged 40–70 who had no diagnosis at baseline in analyses. five that we studied were never smoking, optimal sleep, high level vigorous physical activity, dietary...
The combined effects of low-molecular-weight fucoidan (LMF) and fucoxanthin (Fx) in terms antihyperglycemic, antihyperlipidemic, hepatoprotective activities were investigated a mouse model type II diabetes. intake LMF, Fx, LMF + Fx lowered the blood sugar fasting levels, increased serum adiponectin levels. significant decrease urinary was only observed supplementation. had ameliorating on hepatic tissue db/db mice by increasing glycogen antioxidative enzymes, more effective than at improving...
Recombinant adeno-associated virus (rAAV) has emerged as an important gene therapy vector with many clinical trials currently in progress. Analytical characterization and quantitation of particle content remain challenges both the development production rAAV vectors. In this study, charge detection mass spectrometry (CDMS) gel electrophoresis are used to characterize DNA recombinant AAV8 (rAAV8) vectors a wide range target genome sizes. We show that differences between masses empty particles...
Adeno-associated virus (AAV) is a widely used gene therapy vector. The intact packaged genome critical quality attribute and necessary for an effective therapeutic. In this work, charge detection mass spectrometry (CDMS) was to measure the molecular weight (MW) distribution of interest (GOI) extracted from recombinant AAV (rAAV) vectors. measured MWs were compared sequence masses range rAAV vectors with different GOIs, serotypes, production methods (Sf9 HEK293 cell lines). most cases,...
Summary The viral genome‐linked protein, VP g, of potyviruses is involved in genome replication and translation. To determine host proteins that interact with Sugarcane mosaic virus ( SCMV ) a yeast two‐hybrid screen was used maize Zea mays Elongin C (ZmElc) protein identified. Zm ELC transcript observed all organs, but most highly leaves pistil extracts, ZmElc present the cytoplasm nucleus cells presence or absence . expression increased tissue at 4 6 d post inoculation. When transiently...
Abstract Global warming increases sea temperature and leads to high stress, which affects the yield quality of Pyropia haitanensis . To understand molecular mechanisms underlying stress in a tolerance strain Z-61, iTRAQ technique was employed reveal global proteomic response Z-61 under different durations stress. We identified 151 differentially expressed proteins classified them into 11 functional categories. The 4 major categories these are protein synthesis degradation, photosynthesis,...
Melatonin is a functionally conserved broad-spectrum physiological regulator found in most biological organisms nature. Enrichment of tomato fruit with melatonin not only enhances its agronomic traits but also provides extra health benefits. In this study, we elucidate the full biosynthesis pathway by identifying biosynthesis-related genes that encode caffeic acid O-methyltransferase 2 (SlCOMT2) and N-acetyl-5-hydroxytryptamine-methyltransferases 5/7 (SlASMT5/7). We further reveal red light...
Thrips-transmitted viruses cause devastating losses to numerous food crops worldwide. For negative-sense RNA that infect plants, the arthropod serves as a host well by supporting virus replication in specific tissues and organs of vector. The goal this work was identify thrips proteins bind directly viral attachment protein thus may play role infection cycle insect. Using model plant bunyavirus tomato spotted wilt (TSWV), most efficient vector, we identified validated six TSWV-interacting...
Peanut embryo development is a complex process involving series of gene regulatory pathways and easily affected by various elements in the soil. Calcium deficiency soil induces early abortion peanut, which provides an opportunity to determine mechanism underlying this important event. MicroRNA (miRNA)-guided target regulation vital wide variety biological processes. However, whether miRNAs participate peanut under calcium has yet be explored. In study, with assistance recently established...
The brown marmorated stink bug (Halyomorpha halys) has emerged as one of the most important invasive insect pests in United States. Functional genomics H. halys remains unexplored molecular resources this have recently been developed. To facilitate functional research, we evaluated ten common housekeeping genes (RPS26, EF1A, FAU, UBE4A, ARL2, ARP8, GUS, TBP, TIF6 and RPL9) for their stability across various treatments halys. Our included two biotic factors (tissues developmental stages)...
Epigenetic machinery regulates the expression of individual genes and plays a crucial role in globally shaping maintaining developmental patterning. We studied extent DNA methylation nucleus, mitochondrion chloroplast cultured Sequoia sempervirens (coast redwood) adult, juvenile rejuvenated shoots by measuring ratio methylcytosine to total cytosine using high‐performance liquid chromatography (HPLC). also analyzed nuclear (nuDNA) polymorphisms different shoot types methylation‐sensitive...
Insects are the most important epidemiological factors for plant virus disease spread, with >75% of viruses being dependent on insects transmission to new hosts. The black-faced leafhopper (Graminella nigrifrons Forbes) transmits two that use different strategies transmission: Maize chlorotic dwarf (MCDV) which is semi-persistently transmitted and fine streak (MFSV) persistently propagatively transmitted. To date, little known regarding molecular cellular mechanisms in regulate process...
The advance of next-generation sequencing technology has dramatically reduced the cost genome sequencing. However, processing and analyzing huge amounts data collected from sequencers introduces significant computation challenges, these have become bottleneck in many research clinical applications. For such applications, read alignment is usually one most compute-intensive steps. Billions reads generated sequencer need to be aligned long reference genome. Recent state-of-the-art software...
Abiotic and biotic stresses severely affect the growth reproduction of plants crops. Determining critical molecular mechanisms cellular processes in response to will provide biological insight for addressing both climate change food crises. RNA sequencing (RNA-Seq) is a revolutionary tool that has been used extensively plant stress research. However, no existing large-scale RNA-Seq database designed information on stress-specific differentially expressed transcripts occur across diverse...
Bacterial wilt caused by Ralstonia solanacearum is a devastating disease affecting hundreds of plant species, yet the host factors remain poorly characterized. The leucine-rich repeat receptor-like kinase gene AhRLK1, characterized as CLAVATA1, was found to be up-regulated in peanut upon inoculation with R. solanacearum. AhRLK1 protein localized plasma membrane and cell wall. qPCR results showed induced susceptible variety but little changed resistant cultivar after inoculated Hormones such...