A5060960090- Helicobacter pylori-related gastroenterology studies
- Veterinary medicine and infectious diseases
- Toxin Mechanisms and Immunotoxins
- Mycobacterium research and diagnosis
- Clostridium difficile and Clostridium perfringens research
- Bacterial Identification and Susceptibility Testing
- Veterinary Medicine and Surgery
- Bioactive Compounds and Antitumor Agents
- Galectins and Cancer Biology
- Viral gastroenteritis research and epidemiology
- Whipple's Disease and Interleukins
- Urinary Tract Infections Management
- Gastrointestinal disorders and treatments
Ghent University
2019-2021
Instituut voor Landbouw en Visserijonderzoek
2020
University of Antwerp
2019
Bacterial urinary tract infections (UTIs) occur frequently in companion animals and are often treated with antibiotics. However, antimicrobial resistance can severely hamper treatment success. Therefore, susceptibility monitoring is key. UTI isolates were obtained from dogs cats two collection periods (ComPath II: 2013–2014 ComPath III: 2017–2018) as part of CEESA’s programme. Susceptibility testing the (2021 total) was carried out at one central laboratory using agar broth dilution...
Gastric helicobacters (Helicobacter (H.) pylori and non-H. Helicobacter species (NHPHs)) colonize the stomach of humans and/or animals. identification is essential since many them are recognized as human animal pathogens. Currently, can only be differentiated using molecular methods. Differentiation between NHPHs MALDI-TOF MS has not been described before, probably because these poorly represented in current databases. Therefore, we identified 93 gastric isolates 10 different order to...
A combined agar and broth dilution method followed by qPCR was used to determine the antimicrobial susceptibility of feline H. heilmannii ailurogastricus isolates. All isolates showed a monomodal distribution MICs for all agents tested. For heilmannii, bimodal observed azithromycin, enrofloxacin, spectinomycin, lincomycin. Single nucleotide polymorphisms (SNPs) were found in 50S ribosomal proteins L2 L3 isolate not belonging WT population 30S S1, S7, S12 spectinomycin. The resistance...
Antimicrobial resistant (AMR) bacteria constitute a global health concern. Helicobacter pylori is Gram-negative bacterium that infects about half of the human population and major cause peptic ulcer disease gastric cancer. Increasing resistance to triple quadruple H. eradication therapies poses great challenges urges development novel, ideally narrow spectrum, antimicrobials targeting pylori. Here, we describe antimicrobial spectrum family nitrobenzoxadiazol-based initially discovered as...
In de maag van meer dan helft honden en katten worden Helicobacter-bacteriën aangetroffen, zowel bij dieren zonder klinische tekens als met chronische maagproblemen. Deze bacteriën kunnen tevens ernstige maagpathologiëen veroorzaken mens. Hoe gastrale helicobacters overgedragen tussen naar mensen is nog niet volledig opgehelderd, maar er wordt gesuggereerd dat direct contact een rol kan spelen. Om na te gaan of speeksel feces zouden fungeren bron transmissie, werd aanwezigheid nagegaan...
Abstract The porcine Helicobacter suis and canine-feline H. heilmannii are gastric species with zoonotic potential. However, little is known about the pathogenesis of human infections these species. To gain more insight into interactions both epithelial cells, we investigated bacterial genes that differentially expressed in a strain after adhesion to cell line MKN7. In vitro -MKN7 binding assays were performed obtain RNA for sequencing analysis. bacteria attached cells (i.e. cases) as well...
The exact etiology of Parkinson’s disease (PD) remains largely unknown, but more and research suggests the involvement gut microbiota. Interestingly, idiopathic PD patients were shown to have at least a 10 times higher prevalence Helicobacter suis (H. suis) DNA in gastric biopsies compared control patients. H. is zoonotic species that naturally colonizes stomach pigs non-human primates can be transmitted humans. Here, we investigated influence infection on progression through...