A5016351065- Aortic aneurysm repair treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Vascular Procedures and Complications
- Cerebrovascular and Carotid Artery Diseases
- Aortic Disease and Treatment Approaches
- Peripheral Artery Disease Management
- Coronary Interventions and Diagnostics
- Cardiovascular Health and Disease Prevention
- Peripheral Nerve Disorders
- Photoacoustic and Ultrasonic Imaging
- Acute Ischemic Stroke Management
- Orthopedic Surgery and Rehabilitation
- Hemodynamic Monitoring and Therapy
- Venous Thromboembolism Diagnosis and Management
- Renal and Vascular Pathologies
- Cardiac Imaging and Diagnostics
- Ultrasound Imaging and Elastography
- Nerve Injury and Rehabilitation
- Elasticity and Material Modeling
- Intracranial Aneurysms: Treatment and Complications
- Advanced X-ray and CT Imaging
- Optical Imaging and Spectroscopy Techniques
- Diagnosis and Treatment of Venous Diseases
- Shoulder Injury and Treatment
- Ultrasound and Hyperthermia Applications
Eindhoven University of Technology
2016-2025
Catharina Ziekenhuis
2016-2025
Radboud University Nijmegen
2016-2025
Biomechanics Institute of Valencia
2020
Maastricht University
2020
Erasmus MC
2003-2018
Erasmus University Rotterdam
2000-2017
Albany Medical Center Hospital
2009
University of North Carolina at Chapel Hill
2009
Center for Vascular Biology Research
2008
Although the initial results of endovascular repair abdominal aortic aneurysms were promising, current evidence from controlled studies does not convincingly show a reduction in 30-day mortality relative to that achieved with open repair.
For patients with large abdominal aortic aneurysms, randomized trials have shown an initial overall survival benefit for elective endovascular repair over conventional open repair. This difference, however, was no longer significant in the second year after procedure. Information regarding comparative outcome more than 2 years surgery is important clinical decision making.We conducted a long-term, multicenter, randomized, controlled trial comparing 351 aneurysm of at least 5 cm diameter who...
Adverse cardiac events are common after vascular surgery. We hypothesized that perioperative statin therapy would improve postoperative outcomes.In this double-blind, placebo-controlled trial, we randomly assigned patients who had not previously been treated with a to receive, in addition beta-blocker, either 80 mg of extended-release fluvastatin or placebo once daily before undergoing Lipid, interleukin-6, and C-reactive protein levels were measured at the time randomization The primary end...
Supervised exercise is recommended as a first-line treatment for intermittent claudication. Combination therapy of endovascular revascularization plus supervised may be more promising but few data comparing the 2 therapies are available.To assess effectiveness claudication compared with only.Randomized clinical trial 212 patients allocated to either or only. Data were collected between May 17, 2010, and February 16, 2013, in Netherlands at 10 sites. Patients followed up 12 months analyzed...
Randomized trials have shown an initial survival benefit of endovascular over conventional open abdominal aortic aneurysm repair but no long-term difference up to 6 years after repair. Longer follow-up may be required demonstrate the cumulative negative impact on higher reintervention rates associated with repair.We updated results Dutch Endovascular Aneurysm Management (DREAM) trial, a multicenter, randomized controlled trial comparing repair, 15 follow-up. Survival and reinterventions were...
Case and single center reports have documented the feasibility suggested effectiveness of endovascular aneurysm repair (EVAR) ruptured abdominal aortic aneurysms (RAAAs), but role value such treatment remain controversial.To clarify these we examined a collected experience with use EVAR for RAAA from 49 centers.Data were obtained by questionnaires centers, updated 13 centers committed to whenever possible included details information on 1037 patients treated 763 open (OR).Overall 30-day...
Objective— In a previous in vitro study we have demonstrated that atherosclerotic plaque components can be characterized with multidetector computed tomography (MDCT) based on differences Hounsfield values (HV). Now evaluated the use of MDCT vivo to characterize and quantify carotid compared histology as reference standard. Methods Results— Fifteen symptomatic patients stenosis (>70%) underwent angiography before endarterectomy (CEA). From each CEA specimen 3 histological sections...
Adverse perioperative cardiac events occur frequently despite the use of beta (beta)-blockers. We examined whether higher doses beta-blockers and tight heart rate control were associated with reduced myocardial ischemia troponin T release improved long-term outcome.In an observational cohort study, 272 vascular surgery patients preoperatively screened for risk factors beta-blocker dose. Beta-blocker dose was converted to a percentage maximum recommended therapeutic Heart ischemic episodes...
BackgroundA direct comparison of severe acute respiratory syndrome coronavirus 2 positive patients with a negative control group undergoing an operative intervention during the current pandemic is lacking, and reliable estimate assumed difference in morbidity mortality between both patient categories remains unknown.MethodsWe included all consecutive confirmed pre- or postoperative status (operated 27 hospitals) 4 emergency elective operations. A propensity score-matched clinical outcomes...
Endovascular therapy is a rapidly evolving field for the treatment of patients with peripheral arterial disease, and magnitude studies reporting on various modern revascularization concepts have been recently published. Thus, assessing efficacy endovascular arteries do not operate uniformly defined endpoints, rendering direct comparison difficult. The purpose this consensus statement to highlight differences in terminology used current literature propose some standardized criteria that must...
PURPOSE: To prospectively evaluate clinical utility, patient outcomes, and costs of contrast material–enhanced magnetic resonance (MR) angiography compared with multi–detector row computed tomographic (CT) for initial imaging in the diagnostic work-up patients peripheral arterial disease. MATERIALS AND METHODS: Institutional review board approval informed consent were obtained. Patients referred to feasibility a revascularization procedure randomly assigned undergo either MR or CT...
Purpose: To determine long-term results of the prospective Dutch Iliac Stent Trial. Materials and Methods: The study protocol was approved by local institutional review boards. All patients gave written informed consent. Two hundred seventy-nine (201 men, 78 women; mean age, 58 years) with iliac artery disease were randomly assigned to undergo primary stent placement (143 patients) or percutaneous transluminal angioplasty (PTA) selective in cases which residual pressure gradient greater than...
To determine the incidence of symptomatic and asymptomatic cerebral ischemic lesions found on diffusion-weighted magnetic resonance imaging (DW-MRI) after carotid interventions.A prospective study was conducted to assess new using DW-MRI in patients with artery disease undergoing protected stenting (CAS) or endarterectomy (CEA). performed before intervention 44 (21 CAS 23 CEA). Two experienced radiologists not involved procedures neurological assessment compared postprocedural DW-MR images...
The fibrous cap of an atherosclerotic plaque may be prone to rupture if the occurring stresses exceed strength cap. Rupture can cause acute thrombosis and subsequent ischaemic stroke or myocardial infarction. A reliable prediction probability is essential for appropriate treatment atherosclerosis. Biomechanical models, which compute strain, are promising provide a more risk prediction. However, these models require knowledge local biomechanical properties tissue. For this purpose, we...
PURPOSE: To prospectively compare therapeutic confidence in, patient outcomes (in terms of quality life) after, and the costs digital subtraction angiography (DSA) with those multi–detector row computed tomographic (CT) as initial diagnostic imaging test in patients peripheral arterial disease (PAD). MATERIALS AND METHODS: Institutional medical ethics committee approval informed consent were obtained. Between April 2000 August 2001, PAD randomly assigned to undergo either DSA or CT test....
Purpose: To evaluate retrospectively the effect of vessel wall calcifications on clinical utility multi–detector row computed tomographic (CT) angiography performed in patients with peripheral arterial disease and to identify predictors for presence calcifications. Materials Methods: The study was approved by hospital institutional review board, informed consent obtained from all patients. For this authors included two randomized controlled trials that measured costs effects diagnostic...