A5053239604- Mycobacterium research and diagnosis
- Tuberculosis Research and Epidemiology
- Pneumonia and Respiratory Infections
- Influenza Virus Research Studies
- Bacterial Infections and Vaccines
- Infectious Diseases and Tuberculosis
- Bartonella species infections research
- Respiratory viral infections research
- Viral Infections and Vectors
- Pneumocystis jirovecii pneumonia detection and treatment
- SARS-CoV-2 and COVID-19 Research
- Vector-borne infectious diseases
- Mosquito-borne diseases and control
- Infectious Diseases and Mycology
- Nosocomial Infections in ICU
- Diagnosis and treatment of tuberculosis
- Enterobacteriaceae and Cronobacter Research
- Viral Infections and Outbreaks Research
- COVID-19 epidemiological studies
- COVID-19 Clinical Research Studies
- Infection Control in Healthcare
- Legionella and Acanthamoeba research
- Muscle and Compartmental Disorders
- Paleopathology and ancient diseases
- Infection Control and Ventilation
bioMérieux (France)
2015-2024
Eurofins (France)
2016-2023
Institut Pasteur
2017
CHU Dijon Bourgogne
2017
Centre Hospitalier Universitaire de Lille
2017
Hopitaux Civils de Colmar
2017
Centers for Disease Control and Prevention
2017
Santé Publique France
2017
University Hospital of Geneva
2006
Assistance Publique Hôpitaux de Marseille
1999-2002
We aimed to investigate the first Omicron cases detected in France order assess case characteristics and provide supporting information on possible impact of this variant healthcare system. A standardized questionnaire was used collect from confirmed probable cases. Median age 468 investigated 35 years, 376 were symptomatic (89%); 64% vaccinated with two doses 7% had received three doses. Loss smell taste reported by 8.3% 9% cases, respectively. Seven hospitalized, those unvaccinated...
BackgroundInterventions to mitigate the COVID-19 pandemic may impact other respiratory diseases.AimsWe aimed study course of pertussis in France over an 8-year period including beginning and its association with mitigation strategies, using multiple nationwide data sources regression models.MethodsWe analysed number French cases between 2013 2020, PCR test results from outpatient laboratories (Source 1) a network paediatric wards 41 hospitals 2). We also used reports national primary care...
To determine the role of nonmedicated soap as a source Serratia marcescens nosocomial infections (NIs) in hospital units with endemic S NI and to examine mechanisms colonization.University-affiliated tertiary-care hospitals.A prospective case-control study an environmental investigation were performed assess relationship between NIs marcescens-contaminated soap. Soap-bottle use handwashing practices reviewed. Cultures healthcare workers' (HCWs) hands obtained before after hand washing soap.5...
To describe a nosocomial influenza A outbreak, how it was managed, what impact had on subsequent delivery of health care, and the additional charges attributable to itProspective cohort study microbiological investigation.One internal medicine unit in an acute university-affiliated hospital.Twenty-three patients 22 staff members from February 28 March 6, 1999.Attack rates were 41% (9 22) among 23% (5 members, with 3 14 cases being classified as "certain." The virus isolates typed...
ABSTRACT A single team has reported isolation of nanobacteria in human and bovine blood products, as well as, more recently, kidney stones. This raised controversy. To confirm the data, we searched for from 10 aseptically removed upper urinary tract (UUT) We used scanning electronic microscopy (SEM) with four stones culture on either 3T6 fibroblast monolayers or liquid RPMI medium. Detection was made a commercially available monoclonal antibody, 16S ribosomal DNA amplification specific...
We report detection of Seoul virus in 3 patients France over a 2-year period. These accounted for the 4 infections among 434 hantavirus (1.7%) reported during this time. More attention should be given to Europe where surveillance has been focused mostly on Puumala and Dobrava-Belgrade hantaviruses.
ABSTRACT Coxiella burnetii , an obligate intracellular bacterium which survives in myeloid cells, causes Q fever humans. We previously demonstrated that virulent C. organisms are poorly internalized by monocytes compared to avirulent variants. hypothesized a differential mobilization of the actin cytoskeleton may account for this distinct phagocytic behavior. Scanning electron microscopy stimulated profound and polymorphic changes morphology THP-1 monocytes, consisting membrane protrusions...
Abstract During June 2017–April 2018, active tuberculosis with Beijing SIT1 isolates was diagnosed in 14 persons living 4 distant cities France. Whole-genome sequencing indicated that these patients belonged to a single transmission chain. sequencing–based laboratory investigations enabled prompt tracing of linked cases improve control.
ABSTRACT Dietzia maris , an environmental actinomycete, has been implicated only once in human disease. We herein report the first D. isolate from a bone biopsy specimen patient hospitalized for total hip prosthesis replacement. Cell wall fatty acid analysis and 16S ribosomal DNA gene sequencing were utilized to achieve its definite identification. This case illustrates usefulness of such methods accurate identification actinomycetes.
Among 275 patients with COVID-19, we found that median blood zinc level was significantly lower in poor clinical outcome (N = 75) as compared to good 200) (840 μg/L versus 970 μg/L; p < 0.0001), suggesting supplementation could be useful for severe COVID-19.
Background The present work relates to identification and a deep molecular characterization of circulating Mycobacterium tuberculosis complex (MTBC) strains in the Rhône-Alpes region, France from 2000 2010. It aimed provide with first snapshot MTBC genetic diversity conjunction bacterial drug resistance, type disease available demographic epidemiologic characteristics over an eleven-year period, south-east France. Methods isolated (n = 2257, 1 isolate per patient) between 2010 were analyzed...
The transmission dynamics of tuberculosis involves complex interactions socio-economic and, possibly, microbiological factors. We describe an analytical framework to infer factors epidemic success based on the joint analysis epidemiological, clinical and pathogen genetic data. derive isolate-specific, distance-based estimates success, we represent success-related time-dependent concepts, namely epidemicity endemicity, by restricting specific time scales. method is applied analyze a...
The agar dilution method is currently considered as the reference for Mycobacterium marinum drug susceptibility testing (DST). As it time-consuming, alternative methods, such E-test, were evaluated M. DST, but without success. SLOMYCO Sensititre(®) panel, recently commercialized by TREK Diagnostic Systems (Cleveland, OH), can be used DST in slow-growing mycobacteria and antimicrobial agents recommended Clinical Laboratory Standards Institute (CLSI) DST. main goal of this work was to evaluate...
Abstract Mycobacterium tuberculosis (Mtb) exhibits a structured phylogeographic distribution worldwide linked with human migrations. We sought to infer how the interactions between distinct populations shape global population structure of Mtb on regional scale. applied recently described timescaled haplotypic density (THD) technique 638 minisatellite-based genotypes from French patients. THD long-term (200 y) timescale indicated that in France had been mostly influenced by Eastern and...
Three confirmed infections with the SARS-CoV-2 B.1.640 variant under monitoring were reported in Normandy, north-western France late November 2021. Investigations led to identification of two events linked same cluster. A total 75 and probable cases reported. All had completed primary vaccination series. Sixty-two older than 65 years. Fifty-six symptoms four hospitalised. This investigation provides preliminary results concerning a limited information currently available.
Unlike diseases caused by Mycobacterium tuberculosis, M. leprae and ulcerans, the epidemiology of pulmonary non-tuberculous mycobacteria (PNTM) has not received due attention in French Guiana. The main objective current study was to define incidence these PNTM infections: NTM (NTM-PD) casual isolation (responsible latent infection or simple colonization). secondary objectives were determine species diversity geographic distribution atypical mycobacteria.A retrospective observational...