- Bacterial Identification and Susceptibility Testing
- Infections and bacterial resistance
- Antibiotic Resistance in Bacteria
- Streptococcal Infections and Treatments
- Cystic Fibrosis Research Advances
- Antimicrobial Resistance in Staphylococcus
- Bacterial biofilms and quorum sensing
- Genomics and Phylogenetic Studies
- Plant Pathogenic Bacteria Studies
- Infective Endocarditis Diagnosis and Management
- Mycobacterium research and diagnosis
- Clostridium difficile and Clostridium perfringens research
- Gut microbiota and health
- Enterobacteriaceae and Cronobacter Research
- Oral microbiology and periodontitis research
- Tuberculosis Research and Epidemiology
- Microbial infections and disease research
- Pneumonia and Respiratory Infections
- Diphtheria, Corynebacterium, and Tetanus
- Antifungal resistance and susceptibility
- Microbial Community Ecology and Physiology
- Pharmaceutical and Antibiotic Environmental Impacts
- Orthopedic Infections and Treatments
- Microbial Applications in Construction Materials
- Urinary Tract Infections Management
Université de Montpellier
2016-2025
Laboratoire HydroSciences Montpellier
2016-2025
Centre National de la Recherche Scientifique
2013-2025
Institut de Recherche pour le Développement
2012-2025
Centre Hospitalier Universitaire de Nîmes
2017-2024
Université de Nîmes
2017-2024
Weatherford College
2022
Département Santé des Plantes et Environnement
2015-2022
Bacterial Virulence and Chronic Infections
2021
Centre Hospitalier Universitaire de Montpellier
2010-2021
Three strains of a hitherto unknown, Gram-negative, tiny, anaerobic coccus were collected from human clinical samples originating skin and soft tissues. The three isolates displayed at least 99.9 % identity in their 16S rRNA gene sequences more than 99.8 dnaK sequences. affiliated to the family Veillonellaceae, coccobacillus Dialister micraerophilus being most closely related species, but there was no 91.1 sequence between this species isolates. Phylogeny based on confirmed that represent...
Clostridium difficile causes antibiotic-associated diarrhoea and pseudomembranous colitis. The main virulence factors of C. are the toxins A (TcdA) B (TcdB). third toxin, called binary toxin (CDT), can be detected in 17% to 23% strains, but its role human disease has not been clearly defined. We report six independent cases patients with suspected having infection due strains from toxinotype XI/PCR ribotype 033 or 033-like, an unusual toxinotype/PCR positive for CDT negative TcdA TcdB. Four...
Background. Necrotizing enterocolitis (NEC) is the most common and serious gastrointestinal disorder among preterm neonates. We aimed to assess a specific gut microbiota profile associated with NEC.
ABSTRACT Carbapenem-resistant Acinetobacter baumannii isolates were obtained from 24 patients between March and May 2004 at the Centre Hospitalier de Polynésie Française, Tahiti, French Polynesia. The multidrug resistant, produced carbapenemase OXA-23, belonged to a single clone presenting several subtypes, suggesting an endemic situation. This study further illustrates global spread of this kind β-lactamase-mediated resistance.
ABSTRACT Six clinical CTX-M-producing isolates of the family Enterobacteriaceae were detected between 1999 and 2000 in different French hospitals. Two strains produced CTX-M-1 CTX-M-3 four CTX-M-14, a mutant Ala-231→Val CTX-M-9. A putative transposable element, ISEcp-1, was located 43 bp upstream all bla CTX-M genes. CTX-M-14-encoding plasmids exhibited similar restriction patterns. The CTX-M-1- CTX-M-3-encoding related to previously reported 1990 France 1998 Poland, respectively.
Among the seven species characterized within genus Veillonella , three ( dispar parvula and atypica ) have so far been isolated from human flora during infectious processes. Sequencing analysis of 16S rDNA rrs has described as best method for identification strains at level since phenotypic characteristics are unable to differentiate between species. sequencing humans showed more than 98 % identity them. Four copies were found in reference all clinical isolates studied. The sequences each...
ABSTRACT Lactobacilli are lactic acid bacteria that widespread in the environment, including human diet and gastrointestinal tract. Some Lactobacillus strains regarded as probiotics because they exhibit beneficial health effects on their host. In this study, long-used probiotic strain rhamnosus 35 was characterized at a molecular level compared with seven reference from casei group. Analysis of rrn operon sequences confirmed L. indeed belongs to species, both temporal temperature gradient...
Six clinical isolates of a hitherto unknown, strictly anaerobic, Gram-negative rod showing fastidious growth were subjected to polyphasic taxonomic study, including phenotypic, genomic and phylogenetic feature analyses. 16S rRNA gene sequenced-based phylogeny revealed that the novel strains represent homogeneous group distant from any recognized species in candidate phylum ‘ Synergistetes ’. The most closely related genus Dethiosulfovibrio , with 88.2–88.7 % sequence similarity. Large-scale...
To investigate the resistance mechanisms of β-lactam-resistant Pseudomonas aeruginosa isolated from cystic fibrosis (CF) patients in France. Two-hundred-and-four P. CF isolates were collected 10 French university hospitals 2007. Their susceptibility to 14 antibiotics and their β-lactams investigated. β-lactamase contents characterized by isoelectric focusing, PCR enzymatic assays. Expression levels efflux pumps intrinsic AmpC quantified reverse transcription real-time quantitative PCR....
Environment is recognized as a huge reservoir for bacterial species and source of human pathogens. Some environmental bacteria have an extraordinary range activities that include promotion plant growth or disease, breakdown pollutants, production original biomolecules, but also multidrug resistance pathogenicity. The versatility life-style involves adaptation to various niches. Adaptation both open environment specific niches major challenge intermediate organisms allowing pre-adaptation...
Background Dietary selenium is of fundamental importance to maintain optimal immune function and enhance immunity during infection. To this end, we examined the effect on macrophage bactericidal activities against Staphylococcus aureus. Methods Assays were performed in golden Syrian hamsters peritoneal macrophages cultured with S. aureus different concentrations selenium. Results Infected selenium-supplemented animals have significantly decreased levels serum nitric oxide (NO) production...
ABSTRACT Achromobacter spp. are opportunistic pathogens of environmental origin increasingly isolated in patients with underlying conditions like cystic fibrosis (CF). Despite recent advances, their virulence factors remain incompletely studied, and siderophore production has not yet been investigated this genus. The aim study was to evaluate the siderophores a large collection variability according strain species. A total 163 strains were including 128 clinical (CF non-CF patients) 35...