Hélène Marchandin

ORCID: 0000-0003-2130-6335
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About
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Research Areas
  • Bacterial Identification and Susceptibility Testing
  • Infections and bacterial resistance
  • Antibiotic Resistance in Bacteria
  • Streptococcal Infections and Treatments
  • Cystic Fibrosis Research Advances
  • Antimicrobial Resistance in Staphylococcus
  • Bacterial biofilms and quorum sensing
  • Genomics and Phylogenetic Studies
  • Plant Pathogenic Bacteria Studies
  • Infective Endocarditis Diagnosis and Management
  • Mycobacterium research and diagnosis
  • Clostridium difficile and Clostridium perfringens research
  • Gut microbiota and health
  • Enterobacteriaceae and Cronobacter Research
  • Oral microbiology and periodontitis research
  • Tuberculosis Research and Epidemiology
  • Microbial infections and disease research
  • Pneumonia and Respiratory Infections
  • Diphtheria, Corynebacterium, and Tetanus
  • Antifungal resistance and susceptibility
  • Microbial Community Ecology and Physiology
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Orthopedic Infections and Treatments
  • Microbial Applications in Construction Materials
  • Urinary Tract Infections Management

Université de Montpellier
2016-2025

Laboratoire HydroSciences Montpellier
2016-2025

Centre National de la Recherche Scientifique
2013-2025

Institut de Recherche pour le Développement
2012-2025

Centre Hospitalier Universitaire de Nîmes
2017-2024

Université de Nîmes
2017-2024

Weatherford College
2022

Département Santé des Plantes et Environnement
2015-2022

Bacterial Virulence and Chronic Infections
2021

Centre Hospitalier Universitaire de Montpellier
2010-2021

Three strains of a hitherto unknown, Gram-negative, tiny, anaerobic coccus were collected from human clinical samples originating skin and soft tissues. The three isolates displayed at least 99.9 % identity in their 16S rRNA gene sequences more than 99.8 dnaK sequences. affiliated to the family Veillonellaceae, coccobacillus Dialister micraerophilus being most closely related species, but there was no 91.1 sequence between this species isolates. Phylogeny based on confirmed that represent...

10.1099/ijs.0.013102-0 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2009-11-03

Clostridium difficile causes antibiotic-associated diarrhoea and pseudomembranous colitis. The main virulence factors of C. are the toxins A (TcdA) B (TcdB). third toxin, called binary toxin (CDT), can be detected in 17% to 23% strains, but its role human disease has not been clearly defined. We report six independent cases patients with suspected having infection due strains from toxinotype XI/PCR ribotype 033 or 033-like, an unusual toxinotype/PCR positive for CDT negative TcdA TcdB. Four...

10.1016/j.nmni.2014.10.003 article EN cc-by-nc-nd New Microbes and New Infections 2014-12-04

ABSTRACT Carbapenem-resistant Acinetobacter baumannii isolates were obtained from 24 patients between March and May 2004 at the Centre Hospitalier de Polynésie Française, Tahiti, French Polynesia. The multidrug resistant, produced carbapenemase OXA-23, belonged to a single clone presenting several subtypes, suggesting an endemic situation. This study further illustrates global spread of this kind β-lactamase-mediated resistance.

10.1128/jcm.43.9.4826-4829.2005 article EN Journal of Clinical Microbiology 2005-09-01

ABSTRACT Six clinical CTX-M-producing isolates of the family Enterobacteriaceae were detected between 1999 and 2000 in different French hospitals. Two strains produced CTX-M-1 CTX-M-3 four CTX-M-14, a mutant Ala-231→Val CTX-M-9. A putative transposable element, ISEcp-1, was located 43 bp upstream all bla CTX-M genes. CTX-M-14-encoding plasmids exhibited similar restriction patterns. The CTX-M-1- CTX-M-3-encoding related to previously reported 1990 France 1998 Poland, respectively.

10.1128/aac.46.2.534-537.2002 article EN Antimicrobial Agents and Chemotherapy 2002-02-01

Among the seven species characterized within genus Veillonella , three ( dispar parvula and atypica ) have so far been isolated from human flora during infectious processes. Sequencing analysis of 16S rDNA rrs has described as best method for identification strains at level since phenotypic characteristics are unable to differentiate between species. sequencing humans showed more than 98 % identity them. Four copies were found in reference all clinical isolates studied. The sequences each...

10.1099/mic.0.26132-0 article EN Microbiology 2003-06-01

ABSTRACT Lactobacilli are lactic acid bacteria that widespread in the environment, including human diet and gastrointestinal tract. Some Lactobacillus strains regarded as probiotics because they exhibit beneficial health effects on their host. In this study, long-used probiotic strain rhamnosus 35 was characterized at a molecular level compared with seven reference from casei group. Analysis of rrn operon sequences confirmed L. indeed belongs to species, both temporal temperature gradient...

10.1128/aem.02286-07 article EN Applied and Environmental Microbiology 2008-03-08

Six clinical isolates of a hitherto unknown, strictly anaerobic, Gram-negative rod showing fastidious growth were subjected to polyphasic taxonomic study, including phenotypic, genomic and phylogenetic feature analyses. 16S rRNA gene sequenced-based phylogeny revealed that the novel strains represent homogeneous group distant from any recognized species in candidate phylum ‘ Synergistetes ’. The most closely related genus Dethiosulfovibrio , with 88.2–88.7 % sequence similarity. Large-scale...

10.1099/ijs.0.65213-0 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2007-11-29

To investigate the resistance mechanisms of β-lactam-resistant Pseudomonas aeruginosa isolated from cystic fibrosis (CF) patients in France. Two-hundred-and-four P. CF isolates were collected 10 French university hospitals 2007. Their susceptibility to 14 antibiotics and their β-lactams investigated. β-lactamase contents characterized by isoelectric focusing, PCR enzymatic assays. Expression levels efflux pumps intrinsic AmpC quantified reverse transcription real-time quantitative PCR....

10.1093/jac/dkt115 article EN Journal of Antimicrobial Chemotherapy 2013-04-29

Environment is recognized as a huge reservoir for bacterial species and source of human pathogens. Some environmental bacteria have an extraordinary range activities that include promotion plant growth or disease, breakdown pollutants, production original biomolecules, but also multidrug resistance pathogenicity. The versatility life-style involves adaptation to various niches. Adaptation both open environment specific niches major challenge intermediate organisms allowing pre-adaptation...

10.3390/genes3020191 article EN Genes 2012-03-26

Background Dietary selenium is of fundamental importance to maintain optimal immune function and enhance immunity during infection. To this end, we examined the effect on macrophage bactericidal activities against Staphylococcus aureus. Methods Assays were performed in golden Syrian hamsters peritoneal macrophages cultured with S. aureus different concentrations selenium. Results Infected selenium-supplemented animals have significantly decreased levels serum nitric oxide (NO) production...

10.1371/journal.pone.0135515 article EN cc-by PLoS ONE 2015-09-04

ABSTRACT Achromobacter spp. are opportunistic pathogens of environmental origin increasingly isolated in patients with underlying conditions like cystic fibrosis (CF). Despite recent advances, their virulence factors remain incompletely studied, and siderophore production has not yet been investigated this genus. The aim study was to evaluate the siderophores a large collection variability according strain species. A total 163 strains were including 128 clinical (CF non-CF patients) 35...

10.1128/spectrum.02953-23 article EN cc-by Microbiology Spectrum 2024-02-05
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