A5016507412- Natural Antidiabetic Agents Studies
- Phytochemicals and Antioxidant Activities
- Medicinal Plants and Neuroprotection
- Electromagnetic Fields and Biological Effects
- Diet, Metabolism, and Disease
- Aluminum toxicity and tolerance in plants and animals
- Moringa oleifera research and applications
- Animal Virus Infections Studies
- Protein Hydrolysis and Bioactive Peptides
- SARS-CoV-2 and COVID-19 Research
- Essential Oils and Antimicrobial Activity
- Pancreatitis Pathology and Treatment
- Nanoparticles: synthesis and applications
- Heavy Metal Exposure and Toxicity
- Proteins in Food Systems
- Molecular Communication and Nanonetworks
- Food composition and properties
- Papaya Research and Applications
- Legume Nitrogen Fixing Symbiosis
- Traditional and Medicinal Uses of Annonaceae
- Hibiscus Plant Research Studies
- Biochemical and Structural Characterization
- Phytase and its Applications
- Heavy Metals in Plants
- Biochemical effects in animals
Afe Babalola University
2015-2024
Landmark University
2024
Ekiti State University
2019-2023
Abstract Background Recent reports have highlighted the significance of plant bioactive components in drug development targeting neurodegenerative disorders such as Alzheimer’s disease (AD). Thus, current study assessed antioxidant activity and enzyme inhibitory aqueous extract Talinum triangulare leave (AETt) well molecular docking/simulation identified phytonutrients against human cholinesterase activities. Methods In vitro assays were carried out to assess 2,2- azinobis...
Humans in modern society are exposed to an ever-increasing number of electromagnetic fields (EMFs) and some studies have demonstrated that these waves can alter brain function but the mechanism still remains unclear. Hence, this study sought investigate effect 2.5 Ghz band radio-frequency (RF-EMF) exposure on cerebral cortex acetylcholinesterase (AChE) activity their mRNA expression level as well locomotor anxiety-linked behaviour male rats. Animals were divided into four groups namely;...
Plant based phytonutrients have been recommended as an alternative in the management of diabetes mellitus (DM), a metabolic disorder that has recognized threat to humans across globe. The current study therefore, sought appraise probable antioxidant and antidiabetic potentials methanolic fraction Annona muricata leaf (MetOHAm) via inhibition carbohydrate-hydrolyzing enzymes such α-amylase α-glucosidase, well analyze for available bioactive components using GC–MS technique. quantification...
Introduction: This study appraised the antioxidant potentials, mineral compositions, and antidiabetic activities of pap water (aqua) extract (PWE) aqueous (AE) from Ocimum gratissimum. Methods: The total phenolic contents (TPC), flavonoid (TFC), ferric reducing powers (FRAP), Fe2+-chelating abilities, 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging enzymes inhibition potentials PWE AE O. gratissimum were evaluated. Additionally, determined using absorptive absorbance...
This study was designed to put into consideration both the in vitro and vivo investigations on Talinum triangulare (Tt), an herbaceous perennial plant that is a native of tropical America one most important vegetables Nigeria.Total phenolic contents (mg GAE/100 g), flavonoid contents, ferric reducing antioxidant properties (FRAP), 2, 2-diphenyl-1-picrylhydrazyl (DPPH), hydroxyl free radical scavenging ability (OH-) iron chelating were carried out using standard described methods while GSH,...
This study evaluated the inhibitory effect of ethyl acetate fraction Solanum macrocarpon L. leaves on cholinergic, monoaminergic, purinergic enzyme activities and identification bioactive compounds. 2,2-azino-bis-3-ethylbenthiazoline-6-sulphonic acid (ABTS), metal ion chelating radicals scavenging activity, total phenolic flavonoid contents were determined using standard methods. The effects S. specified enzymes spectroscopically. Ethyl showed a high ABTS radical activity activity. phenol...
Tea and Mint Extracts Modulate the HSP70 Expression in Preeclamptic Placental ExplantE. Padmini, D. Lavanya, J.Tharani S. Lavanya
Anti-asthmatic and Anti-allergic effects of Thymoquinone on Airway-Induced Hypersensitivity in Experimental AnimalsAmira E. Abd El Aziz, Nesrine S. Sayed, Laila G. Mahran
Reports have implicated diabetes mellitus (DM) and Alzheimer's disease (AD) as some of the global persistent health challenges with no lasting solutions, despite significant inputs modern-day pharmaceutical firms. This study therefore, aimed to appraise in vitro antioxidant potential, enzymes inhibitory activities, well carry out silico on bioactive compounds from polyphenolic-rich extract Hibiscus cannabinus seed (PEHc).In assays were performed PEHc using standard methods while...
Bioactivity assessment of endophytic fungi associated with Centella asiatica and Murraya koengii Archana Nath, Jyoti Pathak SR Joshi
Plant phytonutrients have been harnessed for their various curative properties both in vitro and vivo. In this study African black velvet tamarind (ABVT) fruit pulp was evaluated it antioxidant potentials using chloroform hexane fractions through different parameters. the results; total phenolic contents quantified mg GAE/dried sample extracts were; 14.57 ±5.85 9.78 ±4.61, flavonoid as; 48.58 ±0.00 27.35 while FRAP (µg AAE.g-1 dried sample) lower (298.10 ±0.00) than (1029.81 ±0.00). More...
The alarming rate of diabetes mellitus (DM) globally is bothersome and has drawn the search light researchers on naturally endowed phytonutrients being an alternative in managing menace. Therefore, current study was designed to investigate some antioxidant parameters embedded extract Dialium indium (DI) fruit pulp also, elucidate its antidiabetic potentials through inhibition two key carbohydrate-metabolizing enzymes such as α-amylase intestinal α-glucosidase. Hydro-ethanolic DI used for...
The advent of Wi-Fi connected high technology devices in executing day-to-day activities is fast evolving especially developing countries the world and hence need to assess its safety among others. present study was conducted investigate injurious effect radiofrequency emissions from installed brains young male rats. Animals were divided into four equal groups; group 1 served as control while groups 2, 3, 4 exposed 2.5 Ghz at intervals 30, 45, 60 consecutive days with free access food water...
Aluminum toxicity has become a reason for concern in recent times. This study aimed to evaluate the protective effect of hesperidin and gallic acid aluminum chloride (AlCl3)-induced nephrotoxicity rats. Thirty Wistar rats were randomly divided into six groups five animals apiece. Group one served as control received distilled water while lasted. Animals 2-4 AlCl3 (100 mg/kg/day) throughout study. 3 4 administered 100 mg/kg/day hesperidin, respectively, addition AlCl3. Groups 5 6 treated with...