A5103192517- Thyroid Cancer Diagnosis and Treatment
- Advanced biosensing and bioanalysis techniques
- Biosensors and Analytical Detection
- Carbon and Quantum Dots Applications
- Corneal surgery and disorders
- Dye analysis and toxicity
- Ferroptosis and cancer prognosis
- Electrochemical sensors and biosensors
- Hydrocarbon exploration and reservoir analysis
- Intraocular Surgery and Lenses
- Geological and Geophysical Studies
- Pancreatic and Hepatic Oncology Research
- S100 Proteins and Annexins
- Bladder and Urothelial Cancer Treatments
- Bioinformatics and Genomic Networks
- Retinoids in leukemia and cellular processes
- BRCA gene mutations in cancer
- Advanced Biosensing Techniques and Applications
- Nanocomposite Films for Food Packaging
- RNA modifications and cancer
- Foreign Body Medical Cases
- Advanced Nanomaterials in Catalysis
- Heavy Metal Exposure and Toxicity
- Biomarkers in Disease Mechanisms
- Corneal Surgery and Treatments
Taiyuan Normal University
2025
Chengdu University of Technology
2024
State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation
2024
Henan University
2024
Eastern Hepatobiliary Surgery Hospital
2024
Second Military Medical University
2024
West China Hospital of Sichuan University
2018-2023
Sichuan University
2008-2023
Shaanxi Normal University
2020-2023
Beijing Technology and Business University
2023
Clinical staining and targeting CREB3L1 facilitates precise stratification a potential treatment strategy for thyroid cancer.
Abstract Background Anaplastic thyroid cancer (ATC) is a rare but lethal malignancy, and few systematic investigations on genomic profiles of ATC have been performed in Chinese patients. Methods Fifty-four patients West China Hospital between 2010 to 2020 were retrospectively analyzed, while 29 with available samples sequenced by whole-exome sequencing (WES). The associations alterations clinical characteristics statistically evaluated. Results median overall survival was 3.0 months the...
Background The MDS1 and EVI1 complex locus (MECOM, also called PRDM3) PR domain containing 16 (PRDM16) are two highly related zinc finger transcription factors associated with many malignancies. However, the mechanisms of MECOM PRDM16 in prognosis tumor immune infiltration lung adenocarcinoma (LUAD) remain uncertain. Methods Cancer Genome Atlas (TCGA), Oncomine, UALCAN, GEPIA, TIMER databases were searched to determine relationship between expression PRDM16, clinicopathological features,...
The study was designed to explore the potential relationship of TLR4 and endothelial PAS domain-containing protein 1 (EPAS1) in vivo vitro experiments.Bronchoalveolar lavage fluid (BALF) samples were collected from 55 chronic obstructive pulmonary disease (COPD) patients 25 healthy subjects. differential cell count performed using Wright-Giemsa staining. expression levels TLR5 detected by RT-qPCR. methylation mRNA EPAS1 assayed bisulfite sequencing PCR real-time PCR. correlation also...
Background: Pulmonary mucormycosis, a relatively rare but severe pulmonary fungal disease with high mortality rate, is difficult to diagnose in immunocompromised patients. Conventional cytopathology (CCP) examination of respiratory samples can help detect Mucorales, its diagnostic sensitivity poor. The aim this study was assess the first application liquid-based test (LCT) Mucorales. Methods: A total 33 pairs bronchial brushing from 27 patients diagnosed as mucormycosis by fiberoptic...
To explore the prognosis predicting ability of combined factors, Epstein-Barr virus DNA change level (EBVCL) and tumor volume reduction ratio (TVRR) after inductive chemotherapy (IC), in locally advanced nasopharyngeal carcinoma (LANPC).From 2010 to 2018, 299 LANPC patients were included this retrospective study. Receiver operating characteristic (ROC) curve analysis was performed acquire best critical values. According values EBVCL TVRR, stratified into low- high-risk groups. Kaplan-Meier...
Given the imperative of monitoring organophosphorus pesticides (OPs) residues in ecosystem, here a novel, facile and sensitive fluorescence sensor is presented for rapid detection dimethoate. In this work, surface molecularly imprinted polymer (SMIP) microfluidic technology had been introduced to enhance selectivity portability described methodology. Oil-soluble CdSe quantum dots (QDs) synthesized green way were used as fluorescent material selective dimethoate on basis static quenching...
In this study, taking the Jurassic Lianggaoshan Formation (J 1 l ) tight sandstones in eastern Sichuan Basin as an example, types and well-logging responses of main sedimentological diagenetic facies lacustrine delta-front are investigated based on summarizing sedimentary characteristics reservoir properties. Subsequently, further validation application conducted study area through machine learning. Research results show that J mainly develops subaqueous distributary channels mouth bar sand...
Background It has been debated whether familial non-medullary thyroid carcinoma (FNMTC) is more aggressive and a worse prognosis than sporadic (SNMTC). Our aim was to compare the invasiveness of FNMTC SNMTC by their biological behavior molecular changes. Method Material group mainly compared 106 patients with whom have complete clinicopathological data during 2011–2019 in West China Hospital, Sichuan University, 212 randomly selected cases were included behavior, recurrence mortality,...
Using L-cysteine (L-Cys) modified carbon quantum dots (CQDs) and CdTe (CdTe QDs) as fluorescence signals, we developed a novel dual-channel dual-signal microfluidic paper chip, which enables portable rapid analysis of difenoconazole mancozeb by internal filter effect (IFE) photoinduced electron transfer (PET), respectively. The results indicate that the two single-fluorescence imprinted chips have great stability property, chip composed them can achieve simultaneous detection in mixed...
Objective: To evaluate the clinical safety and diagnostic efficacy of domestic gadoxetate disodium (GdEOBDTPA). Methods: The imaging data from patients with space-occupying liver lesions who underwent GdEOBDTPA enhanced magnetic resonance examination at West China Hospital Sichuan University between January 2020 September were analyzed retrospectively. Clinical indicators evaluated by incidental condition transient severe respiratory motion artifacts (TSM) in arterial phase to assess...