A5031906466- Reproductive tract infections research
- Syphilis Diagnosis and Treatment
- Genital Health and Disease
- Herpesvirus Infections and Treatments
- Viral-associated cancers and disorders
- Bacterial Infections and Vaccines
- Autoimmune and Inflammatory Disorders
- Nail Diseases and Treatments
- Autoimmune Bullous Skin Diseases
- HIV Research and Treatment
- Cervical Cancer and HPV Research
- Parvovirus B19 Infection Studies
- Cytomegalovirus and herpesvirus research
- Fungal Infections and Studies
- Immunodeficiency and Autoimmune Disorders
- Cutaneous lymphoproliferative disorders research
- HIV/AIDS Research and Interventions
- Lymphoma Diagnosis and Treatment
- HIV/AIDS drug development and treatment
- Urologic and reproductive health conditions
- Urticaria and Related Conditions
- Adolescent Sexual and Reproductive Health
- Hepatitis C virus research
- Chronic Lymphocytic Leukemia Research
- Streptococcal Infections and Treatments
Ospedale Maggiore
2008-2025
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2015-2025
University of Milan
1996-2023
Istituti di Ricovero e Cura a Carattere Scientifico
1996-2022
University Dermatology
2022
Institut Universitaire des Systèmes Thermiques Industriels
2015
Azienda Ospedaliero-Universitaria Policlinico - Vittorio Emanuele
2013
Institute of Dermatology
2010
Istituto Superiore di Sanità
2008
Institut Jules Bordet
1999
Gonorrhoea is a major public health concern globally. Of particularly grave that resistance to the extended-spectrum cephalosporins has emerged during most recent years. This guideline provides recommendations regarding diagnosis and treatment of gonorrhoea in Europe. Compared outdated 2009 European guideline, this 2012 up-to-date guidance on, broader indications for testing gonorrhoea; introduction dual antimicrobial therapy (ceftriaxone 500 mg azithromycin 2 g) uncomplicated when...
Gonorrhoea is a major public health concern globally. Increasing incidence and sporadic ceftriaxone-resistant cases, including treatment failures, are growing concerns. The 2020 European gonorrhoea guideline provides up-to-date evidence-based guidance regarding the diagnosis of gonorrhoea. updates recommendations emphasize significantly increasing incidence; broad indications for increased testing with validated quality-assured nucleic acid amplification tests culture; dual antimicrobial...
Mycoplasma genitalium infection contributes to 10-35% of non-chlamydial non-gonococcal urethritis in men. In women, M. is associated with cervicitis and pelvic inflammatory disease (PID) 10-25%. Transmission occurs through direct mucosal contact.Asymptomatic infections are frequent. men, urethritis, dysuria discharge predominate. symptoms include vaginal discharge, or PID - abdominal pain dyspareunia. Symptoms the main indication for diagnostic testing. Diagnosis achievable only nucleic acid...
The European guideline for the management of pelvic inflammatory disease includes evidence-based advice on investigation and treatment (PID). It has been updated to acknowledge role Mycoplasma genitalium as an important cause PID with testing now recommended women presenting possible male partners confirmed M. infection. Recent evidence suggests that serious adverse events are uncommon when using moxifloxacin its use is a first-line therapy, especially in those PID. potential utility MRI...
The novel coronavirus SARS-CoV-2/COVID-19 is rapidly and dramatically spreading throughout the world.We describe clinical histopathological features of 3 Italian patients with different cutaneous presentations COVID-19 infection, observed followed at University Milan. CASE REPORTSCase 1.A 59-year-old woman was admitted to intensive care unit (ICU) Milan bilateral interstitial pneumonia.Three days after admission, she developed widespread erythematous macules on arms, trunk lower limbs (Fig....
Anogenital warts (AGW) can cause economic burden on healthcare systems and are associated with emotional, psychological physical issues.To provide guidance to physicians the diagnosis management of AGW.Fourteen global experts AGW developed in an effort unify international recommendations. Guidance was based published national guidelines evaluation relevant literature up August 2016. Authors provided expert opinion their clinical experiences.A checklist for a patient's initial consultation is...
In spite of its immutable susceptibility to penicillin, Treponema pallidum ( T . ) subsp. continues cause millions cases syphilis each year worldwide, resulting in significant morbidity and mortality underscoring the urgency developing an effective vaccine curtail spread infection. Several technical challenges, including absence vitro culture system until very recently, have hampered efforts catalog diversity strains collected worldwide. Here, we provide near-complete genomes from 196...
This position statement is aimed at front-line clinical practitioners and public health authorities in WHO European Region providing services for people wishing to reduce their risk of acquiring sexually transmitted infections (STIs), including HIV.
Objective: AIDS frequently associates with certain malignancies, including Kaposi's sarcoma, non-Hodgkin's lymphoma (NHL), and anogenital neoplasia. In this study we aimed to define the frequency of infection by human herpesvirus (HHV)-8 throughout spectrum AIDS-related neoplasia in Europe. Design: A tumour panel representative distinct types neoplasms was tested for presence HHV-8 DNA sequences. Autologous uninvolved tissues were also selected cases. Methods: The sequences assayed a...
Mycoplasma genitalium is regarded as a potential pathogen of the human urogenital tract based on prevalence findings several European studies.To determine M in urethral specimens symptomatic patients with nongonococcal urethritis and from asymptomatic attending sexually transmitted disease clinic Milan, to verify clinical efficacy eradication by antibiotic treatment.From May 1998 late April 1999, routine analysis for DNA amplification (polymerase chain reaction) was performed Institute...
The SDF-1 3'A allelic polymorphism has been reported to influence either positively or negatively the progression of human immunodeficiency virus type 1 (HIV-1) disease. Therefore, genotype 729 HIV-1-infected individuals pooled from 3 distinct cohorts was determined. A statistically nonsignificant association between SDF1-3'A/3'A and accelerated disease evident among seroconverters (n=319), but a striking correlation decreased survival after diagnosis AIDS according 1993 definition loss...
Abstract Introduction Indirect immunofluorescence (IIF) employing ethanol-fixed neutrophils (ethN) is still the method of choice for assessing antineutrophil cytoplasmic antibodies (ANCA) in ANCA-associated vasculitides (AAV). However, conventional fluorescence microscopy subjective and prone to high variability. The objective this study was evaluate novel pattern recognition algorithms standardized automated interpretation ANCA patterns. Methods Seventy ANCA-positive samples (20...