A5039731694- Cancer and Skin Lesions
- Genetic and rare skin diseases.
- Dermatological and COVID-19 studies
- Parvovirus B19 Infection Studies
- Dermatological and Skeletal Disorders
- Nonmelanoma Skin Cancer Studies
- Skin and Cellular Biology Research
- Poxvirus research and outbreaks
- Autoimmune and Inflammatory Disorders
- Bacillus and Francisella bacterial research
- Acute Myeloid Leukemia Research
- Cutaneous lymphoproliferative disorders research
- Chemical Safety and Risk Management
- Herpesvirus Infections and Treatments
- Cutaneous Melanoma Detection and Management
- Tumors and Oncological Cases
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Autoimmune Bullous Skin Diseases
- Soft tissue tumor case studies
- Streptococcal Infections and Treatments
- Psoriasis: Treatment and Pathogenesis
- Neurofibromatosis and Schwannoma Cases
- Gastrointestinal disorders and treatments
- Bone and Joint Diseases
- Systemic Sclerosis and Related Diseases
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2017-2025
Ospedale Maggiore
2019-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2023-2025
University of Milan
2017-2023
Vita-Salute San Raffaele University
2023
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2023
University of Parma
2019
Medical University of Graz
2017-2018
The novel coronavirus SARS-CoV-2/COVID-19 is rapidly and dramatically spreading throughout the world.We describe clinical histopathological features of 3 Italian patients with different cutaneous presentations COVID-19 infection, observed followed at University Milan. CASE REPORTSCase 1.A 59-year-old woman was admitted to intensive care unit (ICU) Milan bilateral interstitial pneumonia.Three days after admission, she developed widespread erythematous macules on arms, trunk lower limbs (Fig....
Abstract During the COVID‐19 pandemic, chilblain‐like lesions have been reported in mildly symptomatic children and adolescents. We present four investigated for suspected infection who presented with acral skin findings mild systemic symptoms. Histology from one case showed signs of vasculitis evident fibrin thrombus.
Abstract: Skin manifestations of COVID-19 infections are diverse and new to the dermatology community. We had opportunity examine clinical histopathological features several patients who were divided into 3 groups. The first group included 8 COVID-19–positive hospitalized quarantined at home. second children young adults presented with chilblain erythema, erythema multiforme, urticaria-like lesions. This was negative for gene sequences by polymerase chain reaction but a high risk infection....
The global outbreak of human monkeypox virus (hMPXV1) in 2022 highlighted the usefulness dermatological manifestations for its diagnosis. Infection by thus necessitated inclusion diagnostic repertoire dermatopathology. To assess histopathological and microscopical findings cutaneous lesions related to hMPXV infection, we analyzed skin biopsies from patients with positive MPXV DNA polymerase chain reaction presenting a typical course hMPXV1 infection. most prominent were ascribable pustular...
Inflammatory bowel disease (IBD) pathogenesis has been linked to the aberrant activation of Gut-associated lymphoid tissues against components intestinal microbiota. Although contribution CD4 + T helper cells inflammatory processes is being increasingly acknowledged, functional engagement human invariant natural killer (iNKT) still poorly defined. Here, we evaluated characteristics iNKT during IBD and exploit role mucosa-associated microbiota recognition in triggering cells’ pro-inflammatory...
To evaluate the effect of different experimental staining procedures on color stability and translucency a nano-hybrid resin-based composite (RBC). Forty-eight cylindrical-shaped specimens (10 × 2 mm) were prepared with RBC (Clearfil Majesty ES-2) randomly divided in four groups according to procedure: G1) static immersion solution (coffee) (44 ± 1 °C); G2) cycling between coffee 1°C) distilled water (37 an machine based Arduino, Open Source hardware development platform; G3) cycles as G2 +...
Cutaneous metastases represent 2% of all skin tumours. Their recognition can be challenging, as they may present with different clinical features, consequent frequent delay and failure in diagnosis. To review our series cutaneous metastatic lesions, analyse their frequency according to patient gender, histotype, localization the primary tumour, site metastasis, correlate this data clinicopathological parameters. We conducted a retrospective cases from visceral neoplasms diagnosed...
Objective The rationale for the use of autologous fat grafting in treatment vulvar lichen sclerosus (VLS) consists reduction inflammation, regeneration tissues, volume increase, and pain fiber control. main outcome our study was evaluation patients' satisfaction after treatment. Secondary outcomes included modifications symptoms, psychosexual wellbeing, hydration, histology surgery. Methods Eligible this were women aged 18–85 years with a histological diagnosis VLS who underwent at least one...
Only recently histopathological studies of patients with dermatosis and concomitant SARS-Cov-2 viral infection were published. Seven months into the COVID-19 pandemic, more skin biopsies positive are taking place. We examined histological features 30 from two groups patients: Ten specimens tested for an active systemic associated dermatosis. Twenty not considered COVID-positive (due to PCR swab negativity or at all) cutaneous lesions either showing symptoms (fever, cough, ageusia severe...
Background: Breast cancer with osteoclast-like stromal giant cells (OSGC) is an exceedingly rare morphological pattern of invasive breast carcinoma. The tumor immune microenvironment (TIME) these tumors populated by OSGC, which resemble osteoclasts and show a histiocytic-like immunophenotype. Their role in unknown. osteoclast maturation the bone regulated expression cytokines that are also present TIME tumor-associated macrophages (TAMs). TAMs-mediated anti-tumor pathways miRNAs akin to...
The occurrence of pseudolymphomatous infiltrates in cutaneous lupus erythematosus (cLE) is described mainly panniculitis and tumidus/lymphocytic infiltration the skin (Jessner-Kanof). We collected 15 cases cLE other than tumidus (M:F = 4:11; age range: 23-79 years; mean age: 50.9 median 57 years). Of cases, 9 (60%) were characterized by dense nodular infiltrates. Three (20%) showed an angiocentric pattern with cytological atypia lymphoid cells; 2 (13.3%) a band-like infiltrate mimicking...
Abstract Background Formaldehyde and xylene are two hazardous chemicals widely used in pathology laboratories all over the world. The aim of this work was to survey a large volume lab, measuring exposure workers residents formaldehyde xylene, verify efficacy undertaken preventive actions accomplishment with occupational limit values. Methods Environmental, personal, biological monitoring different lab rooms 29 attendants repeated yearly from 2017 2020. Continuous airborne performed evaluate...
COronaVIrus Disease 19 (COVID-19) is associated with a wide spectrum of skin manifestations, but SARS-CoV-2 RNA in lesional has been demonstrated only few cases.The objective this study was to demonstrate presence samples from patients different COVID-19-related cutaneous phenotypes.Demographic and clinical data 52 COVID-19-associated manifestations were collected. Immunohistochemistry digital PCR (dPCR) performed all samples. situ hybridization (ISH) used confirm the RNA.Twenty out (38%)...
We observed ten children with a papular eruption purpuric features during the SARS-CoV-2 pandemic in Northern Italy (May-December 2020). Histological examination showed signs of SARS-CoV-2-related dermatosis. Evidence nucleocapsid viral proteins using (2019-nCoV) antibody revealed cuticular staining deep portion eccrine glands all cases.