Xin Wen

ORCID: 0000-0003-4864-8255
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About
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Research Areas
  • Foreign Body Medical Cases
  • Airway Management and Intubation Techniques
  • Tracheal and airway disorders
  • Cytokine Signaling Pathways and Interactions
  • Reproductive Physiology in Livestock
  • Retinal Development and Disorders
  • Photoreceptor and optogenetics research
  • Cancer-related molecular mechanisms research
  • Tumors and Oncological Cases
  • Genetic and phenotypic traits in livestock
  • Congenital Diaphragmatic Hernia Studies
  • RNA modifications and cancer
  • Restraint-Related Deaths
  • Healthcare and Venom Research
  • Reproductive System and Pregnancy
  • Ear Surgery and Otitis Media
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • Knee injuries and reconstruction techniques
  • Biochemical Analysis and Sensing Techniques
  • Vascular anomalies and interventions
  • Protein Hydrolysis and Bioactive Peptides
  • Oil Palm Production and Sustainability
  • Medicinal Plants and Bioactive Compounds
  • Bioactive Natural Diterpenoids Research
  • Immune Response and Inflammation

Inner Mongolia Agricultural University
2024-2025

Gansu University of Traditional Chinese Medicine
2025

Shaanxi University of Chinese Medicine
2024-2025

Shandong Normal University
2025

Army Medical University
2025

Yangzhou University
2025

Hospital of Hebei Province
2015-2025

Harbin Institute of Technology
2025

Central South University of Forestry and Technology
2024

Chinese Academy of Medical Sciences & Peking Union Medical College
2024

The rapid evolution of the tourism industry globally has led to an increasing emphasis on service quality and tourist experience. To meet these demands, big data technology been extensively adopted in realm smart tourism. This paper delves into application tourism, focusing its role monitoring enhancement strategies. crucial topic enhancing through data. research aims comprehensively understand establish effective mechanisms, formulate practical improvement By integrating literature...

10.53469/ijomsr.2025.08(01).04 article EN other-oa International Journal of Management Science Research 2025-01-20

Background/Objectives: The success or failure of embryo fixation is crucial for attachment and later development. As an epithelial chorioallantoic placenta-type animal, the horse has a special process implantation, mechanism in horses still unclear. Methods: In this study, structural transcriptomic characteristics endometrial tissue from fixed nonfixed sides 20-day gestation embryos Mongolian were investigated to search important genes potential molecular markers associated with phase equine...

10.3390/genes16020181 article EN Genes 2025-02-01

Introduction: Equine chorionic girdle cells can give rise to the endometrial cup, a structure that secretes equine gonadotropin (eCG). To date, mechanisms underlying proliferation, differentiation, invasion, and hormone secretion of are not fully understood. During human pregnancy, interleukin-6 (IL-6) is maternally expressed stimulate invasion migration syncytiotrophoblast influence synthesis gonadotropin. Although many previous studies reported same upregulation IL-6 during placentation,...

10.3390/ani15030450 article EN cc-by Animals 2025-02-06

Type I interferons (IFN-I) are crucial for the initial defense against viral infections. TBK1 serves as a key regulator in production of IFN-I, with its phosphorylation being essential regulation activity. However, regulatory mechanisms governing activation remain incompletely elucidated. In this study, we validated function Fyn-related kinase (Frk) antiviral innate immune response and identified direct target molecule Frk IFN-β signaling pathway. Furthermore, elucidated mechanism by which...

10.3389/fmicb.2025.1525648 article EN cc-by Frontiers in Microbiology 2025-02-12

Abstract Background ABCC4 (ATP-binding cassette sub-family C member 4) is a transporter protein that primarily localized to the plasma membrane, and its efflux activity associated with progression of various cancers development drug resistance. Cyclic adenosine monophosphate (cAMP) an important biomolecule considered transport substrate ABCC4. However, there currently no direct structural understanding how binds cAMP, mechanisms by which it recognizes diverse range ligands remain poorly...

10.1186/s13578-025-01377-y article EN cc-by Cell & Bioscience 2025-03-27

Corneal diseases can cause severe visual impairment and even blindness, which have been linked to the interruption of corneal epithelial homeostasis. However, underlying molecular mechanisms are largely unknown. In this study, by comparing transcriptomes keratoconus, bacterial keratitis, viral healthy corneas, we found a steady upregulation histone deacetylase 6 (HDAC6) in diseases. Consistently, significant increase HDAC6 was observed mouse corneas with keratitis. Overexpression mice...

10.1038/s44319-025-00438-0 article EN cc-by EMBO Reports 2025-03-28

Objective: To observe the clinical efficacy and safety of traditional Chinese medicine (TCM) detoxifying wash in treatment tinea versicolor with gastrointestinal dampness-heat syndrome. Methods: 93 patients were randomly divided into observation group (48 cases) control (45 cases). This study was a single-blind randomized controlled trial. The treated external application wash, while 1% bifonazole solution. Both groups received for 20 days, 10 days as one course. adverse reactions recorded...

10.1097/gscm.0000000000000059 article EN cc-by-nc-nd Deleted Journal 2025-04-01

Adolescent major depressive disorder (MDD) exhibits complex and heterogeneous alterations of brain functional organization. To understand the neurobiological basis adolescent MDD, we adopted resting-state MRI data used various matrix decomposition approaches to obtain organization gradients, temporal dynamics, information streams. With clustering sensory-association gradient features in our exploratory sample (NMDD = 250 NControls 203), identified two MDD subtypes. Subtype 1 was...

10.1101/2025.03.29.646114 preprint EN 2025-04-03

10.1016/j.asjsur.2025.02.146 article EN cc-by-nc-nd Asian Journal of Surgery 2025-04-01

Acute myeloid leukemia (AML) is a clonal malignancy originating from stem cells, characterized by poor prognosis, underscoring the necessity for novel therapeutic targets and treatment methodologies. This study focuses on Ras homolog family member F, filopodia associated (RHOF), Rho guanosine triphosphatase (GTPase) member. We found that RHOF overexpressed in AML, correlating with an adverse prognosis. Our gain- loss-of-function experiments revealed overexpression enhances proliferation...

10.1016/j.isci.2024.110221 article EN cc-by-nc-nd iScience 2024-06-08

The changes in lipid and microbial during beef storage exert a substantial impact on the overall quality of beef. In this study, lipidomics microbiomics were used to evaluate effects chilled (at 4 °C, CS) superchilled -2 SS) yak tenderloin. data revealed that TG, PS, PI, PE, Car are key factors contributing generation undesirable odor Macrococcus, Lactobacillus, Myroides, Proteobacteria directly affect Integrated analysis metabolites interact with lipids, resulting deterioration meat...

10.1016/j.fochx.2024.101984 article EN cc-by-nc Food Chemistry X 2024-11-08

The pathogenesis of acute lung injury (ALI) is complex and it a common critical illness in clinical practice, seriously threatening the lives critically ill patients, for which no specific molecular marker exists there lack effective methods treatment ALI. present study aimed to investigate mechanism action honeysuckle forsythia based on network pharmacology <em>in vitro</em> modeling. active ingredients targets were predicted using traditional Chinese medicine systems pharmacology, PubChem...

10.3892/br.2024.1720 article EN Biomedical Reports 2024-01-03

Faba bean is an important pulse. It provides proteins for the human diet and used in industrial foodstuffs, such as flours. Drought stress severely reduces yield of faba bean, this can be efficiently overcome through identification application key genes response to drought. In study, PacBio Illumina RNA sequencing techniques were identify pathways candidate involved drought response. During seed germination, a total 17,927 full-length transcripts 12,760 protein-coding obtained. There 1676...

10.3390/ijms25168875 article EN International Journal of Molecular Sciences 2024-08-15

Objective:To investigate the causes of barium aspiration,death rate and cause death in upper gastrointestinal examinations,and to help doctor selecting a reasonable method tract examination.Method:Two cases our hospital was reported,and totally 25 patients 22 articles were obtained pubmed or google shchoolar form 1989 2014.Purpose radiologic studies digestive tract,distribution aspirate,clinical presentation prognosis after aspiration sulfate literature collected.Result:①Aspiration mainly...

10.13201/j.issn.1001-1781.2016.17.006 article EN PubMed 2016-09-05

To analyze and summarize the clinical characteristics, diagnosis, treatment prognosis of benign upper airway space occupancy in infants.

10.13201/j.issn.2096-7993.2024.04.014 article EN PubMed 2024-04-01

The preparation of paraffin sections is an important experimental technique in animal histological research, and key factors that determine the quality a section include dehydration time, waxing drying temperature section. Paraffin obtained from testis tissue adult horses exhibited higher with clear structure complete cell morphology after they underwent gradient for 6 hours, were immersed wax 60 minutes, dried 75-degree oven 15 minutes. detailed, optimized procedures are developed current...

10.14670/hh-18-775 article EN PubMed 2024-06-06

To investigate molecular regulation involved in lactation during pregnancy, this study focused on the transcriptomic profiles of mammary tissue from lactating and non-lactating Mongolian mares at second month gestation. A total 4197 differentially expressed genes were identified by comparing tissues pregnant two different states, including 1974 such as milk protein-related a-s1-casein (

10.3390/ani14162319 article EN cc-by Animals 2024-08-09

Improving vegetable yield and optimizing its quality through nutrient management have long been central to plant nutrition horticultural science. Copper (Cu) is recognized as an essential trace element that promotes growth development. However, the mechanisms by which Cu influences nitrogen (N) metabolism remain largely unknown, with limited studies exploring interaction between varying nitrate-to-ammonium (nitrate/ammonium) ratios. In this study, Chinese cabbage was exposed two...

10.3389/fpls.2024.1427720 article EN cc-by Frontiers in Plant Science 2024-09-25
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