A5022208821- Traumatic Brain Injury and Neurovascular Disturbances
- High Altitude and Hypoxia
- Neuroscience of respiration and sleep
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Health and Disease Prevention
- Neonatal and fetal brain pathology
- Anesthesia and Neurotoxicity Research
- Human Health and Disease
- Cancer, Hypoxia, and Metabolism
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Photonic and Optical Devices
- Neurological Disorders and Treatments
- Photorefractive and Nonlinear Optics
- Respiratory Support and Mechanisms
- Heart Rate Variability and Autonomic Control
- Cardiovascular Disease and Adiposity
- Adipose Tissue and Metabolism
- Advanced Fiber Laser Technologies
- Cardiac Ischemia and Reperfusion
- Acute Ischemic Stroke Management
- Mechanical and Optical Resonators
- Acoustic Wave Resonator Technologies
- GaN-based semiconductor devices and materials
- Cytokine Signaling Pathways and Interactions
- Mitochondrial Function and Pathology
Altai State Medical University
2014-2024
First Pavlov State Medical University of St. Petersburg
2019
Regional State Budget Health Care Institution "Regional Clinical Hospital"
2018
Krasnoyarsk State Medical University
2018
Ioffe Institute
2006-2017
Ministry of Health of the Russian Federation
2016
Research Institute of Physiology and Fundamental Medicine of the Siberian Branch of the Russian Academy of Medical Sciences
2016
Institute of Cytology and Genetics
2008-2016
Russian Academy of Sciences
2002-2014
Academy of Medical Sciences
2008-2014
The review introduces the stages of formation and experimental confirmation hypothesis regarding mutual potentiation neuroprotective effects hypoxia hypercapnia during their combined influence (hypercapnic hypoxia). main focus is on mechanisms signaling pathways involved in ischemic tolerance brain intermittent hypercapnic hypoxia. Importantly, effect exerts a more pronounced compared to separate application. Some systems are associated with predominance hypoxic stimulus (HIF-1α, A1...
We studied the comparative efficacy of independent and combined effects normobaric hypoxia (90mmHg) permissive hypercapnia (50mmHg) in increasing tolerance rats to acute hypobaric hypoxia.We determined time loss pose life duration as a measure assess degree animals by exposing them an altitude 11,500m (barometric=180mmHg).Exposure hypercapnic increased compared exposure or alone.The positive occurred after one exposure, number exposures proportionally hypoxia. The effect on was found be...
Introduction Experimental studies on animals have demonstrated a higher neuroprotective efficacy of hypercapnic hypoxia compared to normocapnic hypoxia. Respiratory training with has shown positive impact the functional state nervous system in children cerebral palsy (CP). It can be presumed that combined effect moderate hypercapnia and will promising for clinical application within context early rehabilitation after ischemic stroke.
Arterial partial pressure alteration of CO2 ((Equation is included in full-text article.)) affects not only the cerebral blood flow velocity but also systemic arterial (BP). At same time, BP can affect flow. The objective present research to study impact (Equation article.)level on cerebrovascular reactivity and as well upon article.)alteration by hypercapnia hypocapnia.Cerebral was recorded means transcranial Doppler both middle arteries (MCAv left right). mean (MAP) studied using finger...
We report the excitation of non-steady-state photoelectromotive force using a uniformly accelerated motion recording light pattern. Such illumination is created by linear frequency modulation interfering beams. The pulsed response observed experimentally in semi-insulating GaAs crystal at wavelength 633 nm. evolution pulse shape vs. sweep rate demonstrated. also discuss possible application effect laser Doppler velocimeters and accelerometers.
We report the experimental investigation of non-steady-state photoelectromotive force in aluminum nitride crystal. The sample is illuminated by an oscillating interference pattern formed two coherent light beams and alternating current detected as a response material. experiments are performed for geometries, where arising photocurrent parallel or perpendicular to optical axis Dependencies signal amplitude versus intensity, temporal spatial frequencies measured. photoelectric parameters...
We report the excitation of non-steady-state photoelectromotive force and two-wave mixing signals using uniformly accelerated motion recording light pattern. Such illumination is created by linear frequency modulation interfering beams. The pulse response predicted theoretically observed experimentally in GaAs Bi12TiO20 crystals at λ=633 nm. evolution shape versus sweep rate demonstrated explained frames developed theory. application effects laser Doppler velocimeters accelerometers...
The review discusses the potential relationship between hypoxia resistance and longevity, influence of carbon dioxide on mechanisms aging mammalian organism, intermittent hypercapnic-hypoxic effects signaling pathways mechanisms. In article, we focused gero-protective efficacy when combined with hypoxia. summarizes possible hypercapnia processes in nervous system. We considered perspective variants application influences for achieving active longevity prospects possibilities developing...
We report the nonresonant excitation of nonstationary holographic currents in an external sinusoidal electric field. The theoretical analysis effect has been performed for conventional model semiconductor with one type partially compensated donor level. demonstrate that application ac field sufficiently increases photocurrent amplitude. At same time frequency transfer function maintains form typical diffusion mechanism excitation. dependencies current amplitude and characteristic cutoff...
We report the resonant excitation of nonstationary holographic currents in photoconductive crystals placed a sinusoidal electric field. The analysis effect is performed for simplest model semiconductor with monopolar photoconductivity. demonstrate that frequency transfer function has maximum at ${\ensuremath{\omega}}_{r}\ensuremath{\simeq}K\ensuremath{\mu}{E}_{0}$ originating from photoconductivity gratings. dependences current amplitude versus effective value ac field ${E}_{0},$ spatial...