Marina Gubina
A5071826045- Forensic and Genetic Research
- Yersinia bacterium, plague, ectoparasites research
- Linguistics and Cultural Studies
- Genetic diversity and population structure
- Forensic Anthropology and Bioarchaeology Studies
- Genomics and Phylogenetic Studies
- Race, Genetics, and Society
- Eurasian Exchange Networks
- Helicobacter pylori-related gastroenterology studies
- Treatment of Major Depression
- Growth Hormone and Insulin-like Growth Factors
- Nutrition, Genetics, and Disease
- Genetic Associations and Epidemiology
- Biochemical effects in animals
- Bipolar Disorder and Treatment
- Postharvest Quality and Shelf Life Management
- Iron Metabolism and Disorders
- Immunodeficiency and Autoimmune Disorders
- IL-33, ST2, and ILC Pathways
- Psoriasis: Treatment and Pathogenesis
- Pediatric health and respiratory diseases
- Neurobiology and Insect Physiology Research
- Maternal and Perinatal Health Interventions
- Pacific and Southeast Asian Studies
- Tryptophan and brain disorders
Institute of Cytology and Genetics
2013-2024
Estonian Biocentre
2003-2018
University of Tartu
2004-2018
Siberian Branch of the Russian Academy of Sciences
2006-2013
Native Americans derive from a small number of Asian founders who likely arrived to the Americas via Beringia. However, additional details about intial colonization remain unclear. To investigate pioneering phase in we analyzed total 623 complete mtDNAs and Asia, including 20 new seven Asia. This sequence data was used direct high-resolution genotyping American 26 populations. Here describe more genetic diversity within founder population than previously reported. The newly resolved...
How and when the Americas were populated remains contentious. Using ancient modern genome-wide data, we found that ancestors of all present-day Native Americans, including Athabascans Amerindians, entered as a single migration wave from Siberia no earlier than 23 thousand years ago (ka) after more an 8000-year isolation period in Beringia. After their arrival to Americas, ancestral Americans diversified into two basal genetic branches around 13 ka, one is now dispersed across North South...
The genetic origins of Uralic speakers from across a vast territory in the temperate zone North Eurasia have remained elusive. Previous studies shown contrasting proportions Eastern and Western Eurasian ancestry their mitochondrial Y chromosomal gene pools. While maternal lineages reflect by large geographic background given Uralic-speaking population, frequency chromosomes origin is distinctively high among European speakers. autosomal variation speakers, however, has not yet been studied...
We sequenced genomes from a ∼7,000 year old early farmer Stuttgart in Germany, an ∼8,000 hunter-gatherer Luxembourg, and seven hunter-gatherers southern Sweden. analyzed these data together with other ancient 2,345 contemporary humans to show that the great majority of present-day Europeans derive at least three highly differentiated populations: West European Hunter-Gatherers (WHG), who contributed ancestry all but not Near Easterners; Ancient North Eurasians (ANE), were most closely...
The history of human populations occupying the plains and mountain ridges separating Europe from Asia has been eventful, as these natural obstacles were crossed westward by multiple waves Turkic Uralic-speaking migrants well eastward Europeans. Unfortunately, material records this region are not dense enough to reconstruct details population history. These considerations stimulate growing interest obtain a genetic picture demographic migrations admixture in Northern Eurasia. We genotyped...
Abstract The Altaian Kazakhs, a Turkic speaking group, now reside in the southern part of Altai Republic south‐central Russia. According to historical accounts, they are one several ethnic and geographical subdivisions Kazakh nomadic group that migrated from China Western Mongolia into region during 19th Century. However, their population history Kazakhs genetic relationships with other groups neighboring Turkic‐speaking populations is not well understood. To begin elucidating history, we...
In 1653, the Patriarch Nikon modified liturgical practices to bring Russian Orthodox Church in line with those of Eastern (Greek) Church, from which it had split 200 years earlier. The Old Believers (staroveri) rejected these changes and continued worship using earlier practices. These actions resulted their persecution by forced them into exile across Siberia. Given history, we investigate whether populations have diverged genetically other Slavic as a result isolation. We also examine...
A set of monoclonal antibodies with specificity for hepatitis B surface antigen (HBsAg) was used subtyping this in sera from indigenous natives, blood donors, and drug users Western Siberia a modified commercial enzyme immunoassay kit HBsAg detection. Three subtypes ratio 36 (78%) ayw2:8 ayw3varB (18%):2 (4%) adw2 were found 46 (100%) HBsAg-positive different aboriginal populations Siberia: the Tundra Nenets, Northern Khanty, Southern Altaians, Kazakhs. Four 81 (57%) ayw2:58 (15 ayw3varA 43...
Previously, it was shown that the HFE gene (associated with human hereditary hemochromatosis) has several haplotypes of intronic polymorphisms. Some haplotype frequencies are race specific and hence can be used in phylogenetic analysis. We assumed analysis Caucasoid patients-living now Western Siberia having diseases associated dietary habits metabolic rate-will allow us to understand processes possible selection during settling northern part Asia.Haplotype Northern Eurasian native recently...
Objective : to study the associations between polymorphic variants of 5-HTTLPR SNP rs25531 A>G gene and sleep disorders in open population able-bodied aged 25–44 years Novosibirsk. Material methods . A representative sample Novosibirsk was surveyed 2013–2016 (403 men, mean age – 34±0.4 years, response 71%; 531 women, 35±0.4 72%). The general examination, included WHO MONICA-psychosocial (MOPSY) program carried out according standard methods. Sleep disturbance assessed using Jenkins scale....