A5072419765- Food Allergy and Anaphylaxis Research
- Contact Dermatitis and Allergies
- Allergic Rhinitis and Sensitization
- Xenotransplantation and immune response
- Probiotics and Fermented Foods
- Cell Adhesion Molecules Research
- Occupational exposure and asthma
- Animal Genetics and Reproduction
- CRISPR and Genetic Engineering
- Escherichia coli research studies
- Celiac Disease Research and Management
- Forensic and Genetic Research
- Eosinophilic Esophagitis
- Protein Hydrolysis and Bioactive Peptides
- Mast cells and histamine
- Horticultural and Viticultural Research
- Chromosomal and Genetic Variations
- Algal biology and biofuel production
- Yersinia bacterium, plague, ectoparasites research
- Meat and Animal Product Quality
- Forensic Anthropology and Bioarchaeology Studies
- Asthma and respiratory diseases
- T-cell and B-cell Immunology
- Marine and coastal ecosystems
- Enzyme Production and Characterization
Laboratoire Reproduction et Développement des Plantes
2019-2022
Centre de recherche Translationnelle en Médecine moléculaire
2021
Centre National de la Recherche Scientifique
1995-2019
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2019
Université Claude Bernard Lyon 1
2019
École Normale Supérieure de Lyon
2019
CEA Grenoble
2017
Université Grenoble Alpes
2017
Commissariat à l'Énergie Atomique et aux Énergies Alternatives
2017
Fondation Jean Dausset-CEPH
2004-2010
The relative contributions to modern European populations of Paleolithic hunter-gatherers and Neolithic farmers from the Near East have been intensely debated. Haplogroup R1b1b2 (R-M269) is commonest Y-chromosomal lineage, increasing in frequency east west, carried by 110 million men. Previous studies suggested a origin, but here we show that geographical distribution its microsatellite diversity best explained spread single source via Anatolia during Neolithic. Taken with evidence on...
It has been often stated that the overall pattern of human maternal lineages in Europe is largely uniform. Yet this uniformity may also result from an insufficient depth and width phylogenetic analysis, particular predominant western Eurasian haplogroup (Hg) H comprises nearly a half European mitochondrial DNA (mtDNA) pool. Making use coding sequence information 267 mtDNA Hg sequences, we have analyzed 830 genomes, 11 European, Near Middle Eastern, Central Asian, Altaian populations. In...
Abstract Background Carbohydrate‐specific I g E antibodies present on nonprimate mammalian proteins were incriminated recently in delayed meat anaphylaxis. The aim of this study was to explore whether anaphylaxis kidney is also associated with galactose‐α‐1,3‐galactose (α G al)‐specific . Methods Fourteen patients pork or beef underwent prick tests and kidney. Some skin Erbitux ® (cetuximab). α al, swine urine proteins, meat, serum albumin cat, r Fel d 1 measured by mmuno CAP αGal levels...
Death domain containing members of the tumor necrosis factor receptor (TNFR) superfamily can induce apoptosis or cell activation. However, mechanisms by which these opposing programs are selected remain unclear. Frequently, NF‐κB activation conveys protection against death. We show that serine/threonine kinase RIP is required for TNF‐induced processed caspase‐8 into a dominant‐negative (DN) fragment during death receptor‐induced apoptosis, thereby leading to blockade NF‐κB‐mediated...
Divercin V41, a class IIa bacteriocin with strong antilisterial activity, is produced by Carnobacterium divergens V41. To express recombinant version of divercin we constructed synthetic gene that encodes the mature V41 peptide and then overexpressed in pET-32b using T7 RNA polymerase promoter Escherichia coli Origami (DE3)(pLysS) strain. The DvnRV41 was expressed as translational fusion protein thioredoxin accumulated cell cytoplasm soluble anti-Listeria active form. purified cleaved to...
Nitric oxide (NO) is an intermediate of the nitrogen cycle, industrial pollutant, and a marker climate change. NO also acts as gaseous transmitter in variety biological processes. The impact environmental needs to be addressed. In diatoms, dominant phylum phytoplankton, was reported mediate programmed cell death response diatom-derived polyunsaturated aldehydes. Here, using Phaeodactylum Pt1 strain, 2E,4E-decadienal supplied micromolar concentration range led nonspecific toxicity. We...
Arylsulphatase activity was identified in cultures of the marine bacterium Alteromonas carrageenovora, using methylumbelliferyl sulphate as substrate. In contrast with most other microbial arylsulphatases, arylsulphatase production A. carrageenovora not repressed by sulphate. The structural gene (atsA) cloned and sequenced. An ORF 984 bp found, specifying a primary translation product 328 amino acids molecular mass 35797 Da. partially purified from cell extracts both recombinant Escherichia...
Conditional gene targeting using the Cre/loxP system enables specific deletion of a in tissue interest. For application Cre‐mediated recombination pigment cells, Cre expression has to be targeted cells transgenic mice. So far, no cell‐specific line been reported and we present discuss our first results on use recombinase cells. A construct was generated where is controlled by promoter mouse dopachrome tautomerase ( Dct ) gene. The functionally tested vitro introduced into Following breeding...
Journal Article Evidence on inhibition of Listeria monocytogenes by divercin V41 action Get access C. Richard, Richard Laboratoire de Microbiologie Alimentaire et Industrielle, ENTIAA, Rue la Géraudière, Nantes cedex, France Search for other works this author on: Oxford Academic Google Scholar A. Brillet, Brillet M.F. Pilet, Pilet H. Prévost, Prévost D. Drider Dr Drider, BP 82225. 44322 cedex 3, (e‐mail: drider@enitiaa‐nantes.fr). Letters in Applied Microbiology, Volume 36, Issue 5, 1 May...
Sulfiredoxin catalyzes the ATP-dependent reduction of overoxidized eukaryotic 2-Cys peroxiredoxin PrxSO(2) into sulfenic PrxSOH. Recent mechanistic studies on sulfiredoxins have validated a catalytic mechanism that includes formation phosphoryl intermediate sulfinyl moiety PrxSO(2), followed by an attack cysteine sulfiredoxin leads to thiosulfinate PrxSO-S-sulfiredoxin. Formation this implies recycling reduced form. In study, we investigated how reductase activity Saccharomyces cerevisiae is...
Algae belonging to the Microchloropsis genus are promising organisms for biotech purposes, being able accumulate large amounts of lipid reserves. These adapt different trophic conditions, thriving in strict photoautotrophic as well concomitant presence light plus reduced external carbon energy sources (mixotrophy). In this work, we investigated mixotrophic responses gaditana (formerly Nannochloropsis ). Using Biolog growth test, which cells loaded into multiwell plates coated with organic...
ABSTRACT Polyclonal antibodies have been generated by immunization of rabbits with a chemically synthesized C-terminal part divercin V41 (DvnCt) conjugated to the carrier protein keyhole limpet hemocyanin (KLH). The sensitivity and reactivity DvnCt-KLH-generated were evaluated enzyme-linked immunosorbent assay (ELISA) using supernatant from cultures 13 representative lactic acid bacterium strains, specificity was confirmed Western blot analysis. Anti-DvnCt-KLH able recognize not only but...
Transcription infidelity (TI) is a mechanism that increases RNA and protein diversity. We found single-base omissions (i.e., gaps) occurred at significantly higher rates in the of highly allergenic legumes. Transcripts from peanut, soybean, sesame, mite allergens contained density gaps than those nonallergens. Allergen transcripts translate into proteins with cationic carboxy terminus depleted hydrophobic residues. In mice, recombinant TI variants peanut allergen Ara h 2, but not canonical...