A5076632244- Helicobacter pylori-related gastroenterology studies
- Underwater Vehicles and Communication Systems
- Magnetic confinement fusion research
- Gastric Cancer Management and Outcomes
- Animal Behavior and Reproduction
- Ionosphere and magnetosphere dynamics
- Plant and animal studies
- Avian ecology and behavior
- Maritime Navigation and Safety
- Gastroesophageal reflux and treatments
- Wave and Wind Energy Systems
- Veterinary medicine and infectious diseases
- Galectins and Cancer Biology
- Fusion materials and technologies
- Water Quality Monitoring Technologies
- Toxin Mechanisms and Immunotoxins
- Fluid Dynamics Simulations and Interactions
- Adaptive Control of Nonlinear Systems
- Robotic Path Planning Algorithms
- Particle accelerators and beam dynamics
- Plasma Diagnostics and Applications
- Neuropeptides and Animal Physiology
- Ship Hydrodynamics and Maneuverability
- Laser-Plasma Interactions and Diagnostics
- Coastal and Marine Dynamics
Matsumoto City Hospital
2020-2024
Toyama Prefectural Central Hospital
2024
Kitasato University
2013-2023
Kitasato Institute Hospital
2000-2023
Toyama Institute of Health
2022-2023
University of Miyazaki
2022
Kyushu Dental University
2022
Yamanashi Prefectural Central Hospital
2011-2020
Osaka National Hospital
2018-2020
Kyushu University
2010-2019
microRNAs (miRNAs) are small non-coding RNAs that can function as endogenous silencers of target genes and play critical roles in human malignancies. To investigate the molecular pathogenesis gastric mucosa-associated lymphoid tissue (MALT) lymphoma, miRNA expression profile was analyzed. microarray analysis with specimens from MALT lymphomas surrounding non-tumor mucosae revealed a hematopoietic-specific miR-142 an oncogenic miR-155 were overexpressed lymphoma lesions. The levels miR-142-5p...
Abstract There are four Debye equations for dilute solutions which can be used to determine the relaxation time of a polar solute molecule. This paper offers critical examination these equations, especially two representative formulas mutually independent. If molecule has non-rigid configuration and times, τ1 τ2, overall internal rotations, respectively, average times will obtained from based on measurements at single frequency. However, analysis this shows that under certain condition (if...
Quercetin, glycosylated form of flavonoid compound, has potent antioxidant and anti-inflammatory properties. In this study, we have investigated the effects quercetin on skin lesion, high-mobility group box (HMGB)1 cascade signalling inflammation in atopic dermatitis (AD) mouse model. AD-like lesion was induced by application house dust mite extract to dorsal NC/Nga transgenic mouse. After AD induction, (50 mg/kg, p.o) administered daily for 2 weeks. We evaluated severity, histopathological...
I studied the cloacal protuberance and copulatory behavior of Alpine Accentor (Prunella collaris) over three breeding seasons in central Japan. In males, seasonal hypertrophy glomus seminales forced posterior wall cloaca to form a bulbous (16 mm maximum observed diameter) which sperm were stored. The female's also protruded from its original position cylindrical protuberance. Its lips swelled turned scarlet. remained swollen for an average 29.3 days, until last egg first clutch was laid....
Abstract Background The clinical significance of non‐ Helicobacter pylori (NHPH) is still unknown. There are many reports NHPH‐infected patients suffering from gastric diseases. Here, we investigated the polymerase chain reaction (PCR) positivity NHPH infection in disease who were negative for H. (Hp) by rapid urease test and pathological observation. Materials methods We collected 296 endoscopically obtained mucosal samples Hp‐negative diagnosed based on a pathology 17 hospitals Japan...
The sustained epidemic of Omicron subvariants severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a worldwide concern, and older adults are at high risk. We conducted prospective cohort study to assess the immunogenicity COVID-19 mRNA vaccines (BNT162b2 or mRNA-1273) in nursing home residents staff between May 2021 December 2022. A total 335 SARS-CoV-2 naïve individuals, including 141 (median age: 88 years) 194 44 participated. Receptor-binding domain (RBD) nucleocapsid (N)...
Both Helicobacter pylori and "Candidatus heilmannii" infections are associated with peptic ulcers, gastric adenocarcinoma, mucosa-associated lymphoid tissue (MALT) lymphomas. However, good animal models of H. clinical diseases rare. In this study, we aimed to establish an model MALT lymphoma. We used a urease-positive mucosal mucus homogenate from cynomolgus monkey maintained in C57BL/6 mouse stomachs. The bacterium the was identified as based on DNA sequence analysis 16S rRNA urease genes....
A new casting method for titanium revealed that the mechanical properties of pure castings were close to those gold alloy and more ductile than Ni-Cr or Co-Cr alloy. In this investigation, a hundred crowns produced tested clinically.The fitness was slightly inferior silver-palladium low but superior nickel-chromium crowns. Only one case each discoloration occlusal wear titaoium crowos have been observed in mouth during two-year period. The degree adhesion plaque cwnors about same among gold,...
By injecting rf power ${P}_{\mathrm{rf}}$ near the lower hybrid frequency into an Ohmically heated plasma end of tokamak discharge in WT-2, rf-driven current-sustained is produced and continues to exist during injection period, toroidal current (${I}_{p}\ensuremath{\sim}10$ kA) being generated by wave only without Ohmic power. The efficiency generation high attains $\frac{{I}_{p}}{{P}_{\mathrm{rf}}}\ensuremath{\approx}0.9$ kA/kW at density...
Helicobacter suis infects the stomachs of both animals and humans, can induce gastric mucosa-associated lymphoid tissue (MALT) lymphomas. It is known that CXC chemokine ligand 13 (CXCL13) highly expressed in Helicobacter-infected mice MALT lymphoma patients, but pathway links activation CXCL13 formation lymphomas remains unclear. In this study, we examined whether neutralization would interfere with follicles including B cells, CD4+T dendritic cells (DCs), follicular DCs (FDCs) germinal...
We evaluated the effect of Bifidobacterium lomgum BB536 (B. longum BB536) on subjective symptoms physical condition healthy adults in a double-blind, randomized, placebo-controlled trial. Two hundred participants were recruited and randomized into two groups (BB536 group: n = 100; placebo 100) based frequency with which they experienced cold during three years prior to study. The consumed either powder containing 1 × 1010 colony forming units (CFU) B. or once daily for 12 weeks, their health...
In this paper, we report on highly asymmetric spectrum of electrons observed at the boundary postplasmoid plasma sheet (PPPS). The data were obtained when GEOTAIL made repeated crossings after encountering with a tailward flowing plasmoid X GSM ∼ −46 R E . spectrum, in 0.1–1 keV energy range are seen to flow earthward along lobe‐like field lines into PPPS counter more energetic components (ions and electrons) leaking from PPPS. region, streaming even almost disappear, which makes us...
By injection of microwave power ${P}_{\mathrm{EC}}$ near the electron cyclotron (EC) frequency into an Ohmically heated (OH) plasma in WT-2 tokamak after OH is shut off, current sustained and ramped up by EC wave only, without power. Here, EC-driven generated heating suprathermal beam plasma. Further, when injected lower-hybrid- (LH-) driven current, its rampup rate increase. mildly relativistic electrons LH-driven
We are now developing a prototype of 3000-m class underwater glider for virtual mooring. The vehicle glides back and forth between the sea surface seabed collecting ocean data at specific point. Hydrodynamic forces acting on half-size model were measured to determine optimal wing shape. Next, obtain dynamical-hydrodynamic coefficients, forced oscillation tests carried out using optimally shaped model. Finally, motions simulated hydrodynamic coefficients obtained from these experiments....
Significance This study directly demonstrates virulence-associated features of Helicobacter suis infection using isolates obtained from human stomachs. H. is the second-most-prevalent species in stomach, but diagnostic tests for pylori often fail to diagnose suis. does not have orthologs either cytotoxin-associated gene A (CagA) or vacuolating cytotoxin (VacA), two major virulence factors , suggesting that molecular pathogenicity and clinical manifestations caused by are different those ....
Abstract Genetic analysis and culturing techniques for gastric non- Helicobacter pylori (NHPH) are progressing. NHPH is reported to accompany nodular gastritis, MALT lymphoma, mild gastritis. However, only a few cancer cases infected by have been reported. PCR specific H. was performed DNA from mucosa of 282 Korean patients, who were treated with endoscopic submucosal dissection. For more precise strain detection NHPH, NHPH-positive stained immunohistochemistry suis . The Cancer Genome Atlas...
Three‐dimensional structures of reconnection jets are investigated by hybrid simulations. Magnetic is initiated ad‐hoc anomalous resistivity, which uniform in the cross‐tail direction but localized within meridian plane. At interface between jet and pre‐existing plasma sheet ahead it, reconnected field lines piled up density enhanced compression. The becomes unstable to an interchange instability deforms itself into a wavy shape. In non‐linear growth phase, perturbations grow magnetic...