A5002179911- Ginseng Biological Effects and Applications
- Proteoglycans and glycosaminoglycans research
- Polysaccharides and Plant Cell Walls
- Cell Adhesion Molecules Research
- Telomeres, Telomerase, and Senescence
- DNA Repair Mechanisms
- Muscle Physiology and Disorders
- Diet and metabolism studies
- Redox biology and oxidative stress
- Polysaccharides Composition and Applications
- Protease and Inhibitor Mechanisms
- Silk-based biomaterials and applications
- Glutathione Transferases and Polymorphisms
- Exercise and Physiological Responses
- Viral Infectious Diseases and Gene Expression in Insects
- Fungal Biology and Applications
- Gut microbiota and health
- Seaweed-derived Bioactive Compounds
- Gene expression and cancer classification
- Ferroptosis and cancer prognosis
- AI in cancer detection
- Heparin-Induced Thrombocytopenia and Thrombosis
- Metaheuristic Optimization Algorithms Research
- Pharmacological Effects of Natural Compounds
- Neurobiology and Insect Physiology Research
Northeast Normal University
2005-2024
Ferroptosis is inhibited by glutathione peroxidase 4 (GPX4), an antioxidant enzyme that uses reduced (GSH) as a cofactor to detoxify lipid hydroperoxides. As selenoprotein, the core function of GPX4 thiol-dependent redox reaction. In addition GSH, other small molecules such cysteine and homocysteine also contain thiols; yet, whether can exploit directly hydroperoxides inhibit ferroptosis has not been addressed. this study, we found in GPX4-dependent manner. However, inhibits independent GSH...
AMA Jeff I, Fan E, Tian M, Song C, Yan J, Zhou Y. In vivo anticancer and immunomodulating activities of mannogalactoglucan-type polysaccharides from Lentinus edodes (Berkeley) Singer. Central European Journal Immunology. 2016;41(1):47-53. doi:10.5114/ceji.2015.56962. APA Jeff, I., Fan, E., Tian, M., Song, C., Yan, J., & Zhou, (2016). Immunology, 41(1), 47-53. https://doi.org/10.5114/ceji.2015.56962 Chicago Iteku Bekomo, Enxue Meihong Chenyang Jingmin Yifa Zhou. 2016. "In Singer". Immunology...
Biomarker discovery from high-dimensional data is a complex task in the development of efficient cancer diagnoses and classification. However, these are usually redundant noisy, only subset them present distinct profiles for different classes samples. Thus, selecting high discriminative genes gene expression has become increasingly interesting field bioinformatics. In this paper, discrete biogeography based optimization proposed to select good informative relevant algorithm, firstly,...
Abstract Increasing attention is being paid to the mechanistic investigation of exercise‐associated chronic inflammatory disease improvement. Ulcerative colitis (UC) one type bowel with increasing incidence and prevalence worldwide. It known that regular moderate aerobic exercise (RMAE) reduces or risk UC, attenuates progression in UC patients. However, mechanisms this RMAE's benefit are still under investigation. Here, we revealed β‐hydroxybutyrate (β‐HB), a metabolite upon prolonged...
Muscle contraction increases the level of reactive oxygen species (ROS), which has been acknowledged as key signaling entities in muscle remodeling and to underlie healthy adaptation skeletal muscle. ROS inevitably endows damage various cellular molecules including DNA. DNA ought be repaired ensure genome integrity; yet, how repair byproducts affect remains elusive. Here, we showed that exercise elicited generation 8-oxo-7,8-dihydroguanine (8-oxoG), was primarily found mitochondrial...
With the development of medicine and sport science, growing attention has been paid to recovery exercise-induced fatigue. Ginseng pectin shown be important for a variety biological functions. Although many studies suggest that ginseng plays an role in alleviation fatigue, underlying mechanism still remains unclear. In this study, C57BL/6J mice were subjected wheel apparatus exhaustive exercise fed with WGPA (acidic fraction water-soluble polysaccharides) afterwards. Subsequently, series...
Abstract During exercise, muscle contraction increases the level of reactive oxygen species (ROS), which has been acknowledged as key signaling entities in remodeling and to underlie healthy adaptation skeletal muscle. ROS inevitably endows damage genomic DNA myofibers, ought be repaired ensure integrity fidelity genetic materials; yet, how repair metabolites affect remains elusive. Here, we demonstrated that exercise induces 8-oxo-7,8-dihydroguanine (8-oxoG) generation nuclei myofiber,...