A5078658019- Ion Transport and Channel Regulation
- Plant Stress Responses and Tolerance
- Plant nutrient uptake and metabolism
- Plant Molecular Biology Research
- MicroRNA in disease regulation
- Endometrial and Cervical Cancer Treatments
- Menopause: Health Impacts and Treatments
- Lung Cancer Treatments and Mutations
- RNA Research and Splicing
- Biochemical Analysis and Sensing Techniques
- Gastric Cancer Management and Outcomes
- Photosynthetic Processes and Mechanisms
- RNA modifications and cancer
- Insect-Plant Interactions and Control
- Solar-Powered Water Purification Methods
- Ovarian cancer diagnosis and treatment
- Estrogen and related hormone effects
- Advanced Technologies in Various Fields
- Breast Lesions and Carcinomas
- Advanced Breast Cancer Therapies
- Ferroptosis and cancer prognosis
- Autophagy in Disease and Therapy
- Axon Guidance and Neuronal Signaling
- Reconstructive Surgery and Microvascular Techniques
- Silkworms and Sericulture Research
Northeast Forestry University
2019-2025
Casma Therapeutics (United States)
2025
Wenzhou Medical University
2012-2023
Yueqing People's Hospital
2022
Liuzhou Maternal and Child Health Hospital
2020-2022
First Affiliated Hospital of Xi'an Jiaotong University
2020-2021
Shandong University of Arts
2020
Northwest University
2020
Army Medical College
2020
Army Medical University
2020
INTRODUCTION: Although the 9-minute mean withdrawal time (m-WT) is often reported to be associated with optimal adenoma detection rate (ADR), no randomized trials of screening colonoscopy have confirmed impact a m-WT on miss (AMR) and ADR. METHODS: A multicenter tandem trial was conducted in 11 centers. Seven hundred thirty-three asymptomatic participants were receive segmental withdrawal, followed by 6-minute (9-minute-first group, 9MF, n = 366) or vice versa (6-minute-first 6MF, 367). The...
MOMA-341, first disclosed herein, is a novel, potent, and selective clinical stage small molecule inhibitor of the Werner RecQ like helicase (WRN) that acts through an allosteric, ATP-competitive binding mechanism covalent ligation WRN at cysteine 727. Consistent with genetic depletion in MSI-H models, MOMA-341 induces DNA damage, cell death, tumor regressions mismatch-repair deficient (dMMR)/microsatellite instability high (MSI-H) models but has no effect MSS or lines derived from normal...
Aquaporins (AQPs) serve as water channel proteins and belong to major intrinsic (MIPs) family, functioning in rapidly selectively transporting other small solutes across biological membranes. Importantly, AQPs have been shown play a critical role abiotic stress response pathways of plants. As species closely related Arabidopsis thaliana, Eutrema salsugineum has proposed model for studying salt resistance Here we surveyed 35 full-length AQP genes E. salsugineum, which could be grouped into...
Salt stress severely restricts plant growth and crop production, which is accompanied by accumulation of reactive oxygen species (ROS) that disturb cell redox homeostasis oxidize redox-sensitive proteins. Eutrema salsugineum, a halophytic closely related to Arabidopsis, shows high level tolerance salinity increasingly used as model in abiotic biology. To understand modifications signaling pathways under salt stress, we tandem mass tag (TMT)-based proteomics quantify the salt-induced changes...
Response to crizotinib in a lung adenocarcinoma patient harboring novel SLC34A2-ROS1 fusion variant Zheng Zhao,1 Zhangjun Song,2 Xuwei Wang,3 Haifeng Sun,1 Xiaomin Yang,2 Yong Yuan,4 Pan Yu3 1Third Department of Medical Oncology, Shannxi Provincial Cancer Hospital, 2Breast Surgery Center, Xi'an, 3Marketing Department, Novogene Bioinformatics Institute, Beijing, 4Pathology People's Republic China Abstract: ROS1 is common genetic alteration non-small-cell cancer. Crizotinib, an anaplastic...
This study aimed to investigate Chinese physicians' perception and attitudes toward menopausal hormone therapy (MHT).This nationwide online survey was conducted in China. Physicians registered the WeChat groups of Gynecological Endocrinology Committee China's Maternal Child Health Care Association received a message invitation complete this anonymous from April 2020 July 2020. Physicians' knowledge MHT were surveyed.In total, 4672 questionnaires submitted; only completed could be submitted....
Abstract Background With increasing cases of iatrogenic premature ovarian insufficiency (POI), more clinicians are required to counsel patients regarding the gonadotoxic effects treatments. This survey aimed explore obstetricians and gynaecologists’ knowledge POI. A national online questionnaire was conducted across China. Respondents were asked select condition(s) that can cause POI based on their experience knowledge. Results Of 5523 returned questionnaires, 4995 analysed. Among tumour...
Objective To investigate the expressions of Sema4D and HER-2 in breast cancers their relationship with microlymphtic vessel density (MLVD).Methods MLVD were detected 110 cases cancer tissues by immunohistochemistry.The clinicopathologic parameters was analyzed.Results The positive expression rate 71.82％ (79/110) 33.64％ (37/110),respectively,with a statistically significant differences compared to those control group ( P ＜0.01 ).The rates lymphatic metastasis higher than that without ＜ 0.01...
Aquaporins (AQPs) serve as water channel proteins and belong to major intrinsic (MIPs) family, functioned in rapidly selectively transporting other small solutes across biological membranes. Importantly, AQPs have been shown play critical roles abiotic stress response of plants. Eutrema salsugineum is close Arabidopsis thaliana proposed a model system for studying plant salt resistance. Here we identified 35 full-length AQP genes E. . Phylogenetic analysis showed EsAQPs were similar with...
<title>Abstract</title> Background Neural cell adhesion molecule (NCAM), a common mammalian surface glycoprotein, is the major substrate of polysialic acid (polySia). Polysialylated NCAM occurs in many types cancer, but rarely normal adult tissues. Epithelial-mesenchymal transition (EMT) an important process contributing to tumor metastasis. The functional role hypersialylation EMT unclear. Method Expression and polysialylated breast cancer progression were evaluated by western blot (WB),...
Objective To investigate the clinical correlated problems of immediate breast reconstruction with silicagel prosthesis after modified radical mastectomy.Methods From Jun.2007 to Dec.2011,30 patients were treated skin sparing mastectomy and by placing silicone implants into submuscle.15 cases reserved nipple-areola complexes.All routinely operation.Results evaluation operation showed that excellent rate reached 90.0％,and subjective 93.3％.Two suffered under-flap hydrops,one case capsular...
Objective To investigate the clinical significance of early diagnosis and treatment impalpable breast tumor. Methods From Jan. 2007 to Dec. 2014, 570 patients with tumor were treated. Among them, 107 found nodules by ultrasound scan, 340 nodules, calcification or distort gland structure 123 nipple discharge mammography. They biopsied various methods such as wire localization guided ultrasound, X-ray mammography fiberoptic ductoscopy. All treated routinely followed...