A5102730595- Reinforcement Learning in Robotics
- Sperm and Testicular Function
- Genetic and phenotypic traits in livestock
- Genetic Mapping and Diversity in Plants and Animals
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Advanced Bandit Algorithms Research
- Adversarial Robustness in Machine Learning
- Reproductive Biology and Fertility
- MicroRNA in disease regulation
- Machine Learning and Algorithms
- Artificial Intelligence in Games
- Lepidoptera: Biology and Taxonomy
- Genomics and Phylogenetic Studies
- Animal Genetics and Reproduction
- Advanced Nanomaterials in Catalysis
- Nanocluster Synthesis and Applications
- Muscle Physiology and Disorders
- Iron Metabolism and Disorders
- Image and Object Detection Techniques
- Renal and related cancers
- Tuberculosis Research and Epidemiology
- Human Motion and Animation
- Remote Sensing and LiDAR Applications
- Generative Adversarial Networks and Image Synthesis
- Machine Learning in Healthcare
Huazhong Agricultural University
2011-2025
Hunan University
2024-2025
State Key Laboratory of Chemobiosensing and Chemometrics
2024-2025
Leshan Normal University
2024
Chongqing Medical University
2024
The Affiliated Yongchuan Hospital of Chongqing Medical University
2024
Fuwai Yunnan Cardiovascular Hospital
2023
Xiamen University
2020-2022
Tsinghua University
2016-2022
Ministry of Agriculture and Rural Affairs
2018-2020
Near-infrared-II (NIR-II) imaging has emerged as a powerful technique for high-resolution visualization of deep anatomical features, benefiting from minimized autofluorescence, diminished optical scattering, and absorption tissue. However, the current synthesis NIR-II nanoprobes is time-consuming, labor-intensive process with low yields, highlighting need an efficient rapid approach instead. Herein, we report DNA-templated silver nanoclusters (Ag NCs) emission that can be rapidly synthesized...
The escalating demand for gold, coupled with dwindling terrestrial reserves, underscores the urgent need innovative separation strategies, including e-waste recycling and seawater extraction. However, development of ultra-efficient, highly selective adsorbents capable recovering trace amounts gold from complex aquatic matrices remains a formidable challenge. Herein, covalent organic superphane cage is reported as nonporous amorphous superadsorbent (NAS) efficient recovery via intermolecular...
Existing motion capture datasets are largely short-range and cannot yet fit the need of long-range applications. We propose LiDARHuman26M, a new human dataset captured by LiDAR at much longer range to overcome this limitation. Our also includes ground truth motions acquired IMU system synchronous RGB images. further present strong base-line method, LiDARCap, for point cloud capture. Specifically, we first utilize <tex xmlns:mml="http://www.w3.org/1998/Math/MathML"...
Gold nanoclusters (AuNCs) are highly promising for applications in photothermal conversion due to their exceptional surface area and optical properties. However, high energy often leads aggregation, compromising stability performance. To address this, we developed a ferritin‐inspired covalent organic cage with near‐enclosed cavity physically stabilize AuNCs. This superphane coordinates Au3+ ions, forming stable uniform AuNCs upon reduction. The encapsulated exhibit broad absorption (250–2500...
Abstract A growing number of reports have revealed that microRNAs (miRNAs) play critical roles in spermatogenesis. Our previous study showed miR-762 is differentially expressed immature and mature testes Large White boars. present data shows directly binds the 3′ untranslated region (3′UTR) ring finger protein 4 ( RNF4 ) down-regulates expression. single nucleotide polymorphism (SNP) 3′UTR significantly associated with porcine sperm quality traits leads to a change binding ability. Moreover,...
Near-infrared (NIR) heptamethine cyanine (HCy) dyes are promising photothermal transducers for image-guided cancer treatment owing to their prominent photophysical properties and high conversion ability. However, HCy usually have poor photostability due degradation induced by the self-generated reactive oxygen species. Herein, a novel mitochondria-targeting dimeric dye, named oBHCy, is rationally designed, exhibiting strong near-infrared II (NIR-II) fluorescence emission, efficiency (PCE),...
Numerous studies have demonstrated that microRNAs (miRNAs) play important roles in cell growth, apoptosis and spermatogenesis. Our previous study showed miR-638 was differentially expressed sexually immature mature testes of Large White boars. Here we reported sperm-associated antigen 1 (SPAG1) a direct target gene miR-638. Moreover, inhibited proliferation cycle, promoted porcine Sertoli cells. Key genes including phosphorylated phosphatidylinositide 3-kinases (p-PI3K) serine/ threonine...
Abstract Some documented evidences proved small RNAs (sRNA) and targeted genes are involved in mammalian testicular development spermatogenesis. However, the detailed molecular regulation mechanisms of them remain largely unknown so far. In this study, we obtained a total 10,716 mRNAs, 67 miRNAs 16,953 piRNAs which were differentially expressed between LC LW pig breeds or two sexual maturity stages. Of which, identified 16 28 possibly related to spermatogenesis; 14 miRNA 18 probably...
Maximum mean discrepancy (MMD) has been successfully applied to learn deep generative models for characterizing a joint distribution of variables via kernel embedding. In this paper, we present conditional moment- matching networks (CGMMN), which given some input based on maximum (CMMD) criterion. The learning is performed by stochastic gradient descent with the calculated back-propagation. We evaluate CGMMN wide range tasks, including predictive modeling, contextual generation, and Bayesian...
Engineering Saccharomyces cerevisiae for biodegradation and transformation of industrial toxic substances such as catechol (CA) has received widespread attention, but the low tolerance S. to CA limited its development. The exploration modification genes or pathways related in is an effective way further improve utilization efficiency CA. This study identified 36 associated with through genome-wide identification bioinformatics analysis ERG6 knockout strain ( Δ) most sensitive Based on omics...
Gold nanoclusters (AuNCs) are highly promising for applications in photothermal conversion due to their exceptional surface area and optical properties. However, high energy often leads aggregation, compromising stability performance. To address this, we developed a ferritin-inspired covalent organic cage with near-enclosed cavity physically stabilize AuNCs. This superphane coordinates Au3+ ions, forming stable uniform AuNCs upon reduction. The encapsulated exhibit broad absorption (250-2500...
AnnexinA5 (ANXA5) has been identified as a positional candidate gene for reproduction and fertility traits in boars, but its role testicular tissue development, well genetic variations remain unclear. The aim of this study was to explore the effect ANXA5 growth swine Sertoli cells identify functional variations. Firstly, expression porcine different tissues detected by semi-quantitative RT-PCR on proliferation evaluated CCK8, EdU, flow cytometry analyses qRT-PCR. Then, putative causative...
Sertoli cells contribute to the formation of blood-testis barrier (BTB), which is necessary for normal spermatogenesis. Recently, microRNAs (miRNAs) have emerged as posttranscriptional regulatory elements in BTB function during Our previous study has shown that miR-181c or miR-181d (miR-181c/d) highly expressed testes from boars at 60 days old compared with 180 old. Herein, we found overexpression miR-181c/d via mimics murine (SCs) through injecting miR-181c/d-overexpressing lentivirus...
The MYF5 gene is first inducibly expressed in muscle cell during embryonic development and plays an important role regulating the differentiation of skeletal precursors. In this study we used PCR-RFLP to investigate two pig (Sus scrofa) populations (n = 302) for polymorphisms, a previously unreported novel Met-Leu shift single nucleotide polymorphism (SNP) MYF5/Hsp92II located on exon 1 identified intron MYF5/HinfI SNP. Haplotype association analysis showed that haplotypes SNPs were...
We took part in the YouTube-8M Video Understanding Challenge hosted on Kaggle, and achieved 10th place within less than one month's time. In this paper, we present an extensive analysis solution to underlying machine-learning problem based frame-level data, where major challenges are identified corresponding preliminary methods proposed. It's noteworthy that, with merely proposed strategies uniformly-averaging multi-crop ensemble was it sufficient for us reach our ranking. also report...
Abstract Using Affymetrix porcine Gene-Chip analyses, we found that Dickkopf2 ( DKK2 ), a WNT antagonist, is differentially expressed in pre-ovulatory follicles between Large White and Chinese Taihu sows. This study aims to identify the regulatory factors responsible for expression. Deletion fragment mutation analyses identified DKK2-D3 as core promoter. There were four C/EBPβ binding sites within The C allele results from spontaneous alteration c.−1130 T > C) promoter was associated with...
The complete mitochondrial genome of N. schrenkii is 15,261 bp in length, containing 13 protein-coding genes (PCGs), 22 transfer RNA (tRNAs), 2 ribosomal (LrRNA and SrRNA) 1 non-coding A + T-rich region. nucleotide composition significantly biased toward T (80.2%), similar to the known satyrid species. All PCGs utilize typical start codon ATN, except for COI, which initiated with CGA. Seven use stop (TAA), whereas ND1 ND4 TA as COII ND5 end single T. region 403 contains several features...
BCL2-associated athanogene 6 (BAG6) plays critical roles in spermatogenesis by maintaining testicular cell survival. Our previous data showed porcine BAG6 exon24-skipped transcript is highly expressed immature testes compared with mature testes. The objective of this study to reveal the functional significance exon24 mammalian spermatogenesis.CRISPR/Cas9 system was used generate Bag6 knockout mice. Testes and cauda epididymal sperm were collected from TMT proteomics analysis discover protein...
Sperm associated antigen 6 (SPAG6) acts as a scaffolding protein in the center of flagellar axoneme and has an impact on maturation motility mammalian sperm flagella maintenance structure. In our previous research, SPAG6 c.900 T>C exon 7 skipped transcript was identified by analyzing RNA-seq data testicular tissues from 60 day (sexually immature) 180 mature) Large White boars. Herein, we found porcine to be with semen quality traits Duroc, Landrace pigs. C can generate new splice acceptor...