- Colorectal Cancer Surgical Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Frailty in Older Adults
- Nutrition and Health in Aging
- Colorectal and Anal Carcinomas
- Colorectal Cancer Screening and Detection
- Advances in Oncology and Radiotherapy
- Enhanced Recovery After Surgery
- Breast Cancer Treatment Studies
- Stoma care and complications
- Colorectal Cancer Treatments and Studies
- Inflammatory Bowel Disease
- Anorectal Disease Treatments and Outcomes
- COVID-19 and healthcare impacts
- Breast Lesions and Carcinomas
- Diverticular Disease and Complications
- Management of metastatic bone disease
- Appendicitis Diagnosis and Management
- Cancer survivorship and care
- Surgical Simulation and Training
- Global Cancer Incidence and Screening
- Diversity and Career in Medicine
- Healthcare cost, quality, practices
- Infection Control and Ventilation
- Hospital Admissions and Outcomes
Ospedale "Santa Maria delle Croci" di Ravenna
2023-2024
Ospedale Santa Maria
2022-2024
Ospedale per gli Infermi
2019-2023
University of Bologna
2012-2018
Policlinico S.Orsola-Malpighi
2012-2016
Abstract Background Accurate quality of life (QoL) data and functional results after cancer surgery are lacking for older patients. The international, multicenter Geriatric Oncology Surgical Assessment Functional rEcovery Surgery (GOSAFE) Study compares QoL before identifies predictors decline in QoL. Methods GOSAFE prospectively collected major elective on adults (≥70 years). Frailty assessment was performed postoperative outcomes recorded (30, 90, 180 days postoperatively) together with by...
The GOSAFE study evaluates risk factors for failing to achieve good quality of life (QoL) and functional recovery (FR) in older patients undergoing surgery colon rectal cancer.
Colorectal cancer (CRC) is the third most common in world. A significant survival rate achieved if it detected at an early stage. whole blood screening test, without any attempt to isolate fractions, could be important tool improve detection of colorectal cancer. We searched for candidate markers with a novel approach based on Transcriptome Mapper (TRAM), aimed identifying specific RNAs highest differential expression ratio between tissue and normal samples. This permits large-scale...
Cancer is one of the most common diagnoses in elderly patients. Of all types abdominal cancer, colorectal cancer (CRC) undoubtedly frequent. Median age at diagnosis approximately 70 years old worldwide. Due to multiple comorbidities affecting people, frailty evaluation very important order avoid over- or under-treatment. This pilot study was designed investigate variables capable predicting long-term risk mortality and living situation after surgery for CRC.Patients with older undergoing...
In view of accumulating evidence supporting a pivotal role the Rho/ROCK pathway in cancer, we investigated Rho-kinase polymorphisms as potential susceptibility factors colorectal cancer (CRC) representative sample Italian population.DNA obtained from peripheral blood samples 137 CRC patients and 141 healthy controls was genotyped for four ROCK1 (rs35996865; rs73963110; rs2127958; rs288980) five ROCK2 (rs12692437; rs7563468; rs35768389; rs17463896; rs16857265) selected single nucleotide...
Abstract Background Senior adults fear postoperative loss of independence the most, and this might represent an additional burden for families society. The number geriatric patients admitted to emergency room requiring urgent surgical treatment is rising, presence frailty main risk factor morbidity functional decline. Frailty assessment in busy setting challenging. aim study verify effectiveness a very simple five-item screening tool, Flemish version Triage Risk Screening Tool (fTRST),...
OBJECTIVES To evaluate long‐term survival and institutionalization in onco‐geriatric surgical patients, to analyze the association between these outcomes a preoperative risk score. DESIGN Prospective cohort study with follow‐up. SETTING International multicenter locations. PARTICIPANTS Patients aged 70 years or older undergoing elective surgery for malignant solid tumor at five centers (n = 229). MEASUREMENTS We assessed using Preoperative Risk Estimation Onco‐geriatric (PREOP) score,...
11511 Background: Older cancer patients value functional outcomes as much survival but surgical studies lack recovery (FR) data. The international, multicenter GOSAFE study (ClinicalTrials.gov NCT03299270) aims to evaluate patients’ quality of life (QoL)and FR after surgery and assess predictors FR. Methods: prospectively collects clinical data before major elective on senior adults (≥70 years). Surgical are recorded (30 days, 90 180 dayspost-operatively) with QoL(EQ-5D-3L) (Activities Daily...
Background Although the majority of patients with Crohn's disease (CD) are young, they often seriously ill when surgery is required. The Physiological and Operative Severity Score for enUmeration Mortality morbidity (POSSUM) a risk prediction scoring system estimating 30-day complications. primary endpoint was to evaluate POSSUM efficacy in this subgroup. secondary determine any potential correlation between POSSUM, Harvey–Bradshaw Index (HBI), length stay (LOS) anastomotic leak. Methods All...
Multicentric Castleman’s disease is a rare condition of systemic nonclonal lymph node hyperplasia. Because its strong association with human herpes virus 8 (HHV8), the multicentric, more aggressive, form may progress to Kaposi sarcoma or non-Hodgkin lymphoma. While surgery curative in treatment localized disease, operative diffuse has as yet been unsatisfactory. We report case patient presenting postprandial vomiting 1 month duration consistent partial small bowel obstruction secondary...
Background: Managing patients with obstructing rectal cancer is challenging due to the risks of gastrointestinal obstruction and perforation. This study evaluates outcomes pre-emptive laparoscopic colostomy creation in locally advanced anal prevent symptoms facilitate therapy initiation. Methods: retrospective cohort includes or assessed by our Colorectal Multidisciplinary Team from January 2017 February 2024. Patients who underwent were compared a control group non-obstructing started...