Rafael Garza‐Castillon

ORCID: 0000-0003-4970-6584
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Mechanical Circulatory Support Devices
  • Transplantation: Methods and Outcomes
  • COVID-19 Clinical Research Studies
  • Long-Term Effects of COVID-19
  • Respiratory viral infections research
  • Esophageal Cancer Research and Treatment
  • Cardiac Arrest and Resuscitation
  • SARS-CoV-2 and COVID-19 Research
  • Cardiac Structural Anomalies and Repair
  • Organ Transplantation Techniques and Outcomes
  • Airway Management and Intubation Techniques
  • Radiomics and Machine Learning in Medical Imaging
  • Antibiotic Use and Resistance
  • Pleural and Pulmonary Diseases
  • Trauma Management and Diagnosis
  • Dysphagia Assessment and Management
  • Congenital Diaphragmatic Hernia Studies
  • Neonatal Respiratory Health Research
  • Esophageal and GI Pathology
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Metastasis and carcinoma case studies
  • SARS-CoV-2 detection and testing
  • Lung Cancer Diagnosis and Treatment
  • Pneumonia and Respiratory Infections
  • Respiratory Support and Mechanisms

Northwestern Memorial Hospital
2020-2023

Northwestern University
2020-2023

Thoracic Surgery Foundation
2022

University of Minnesota
2016

Some patients with severe COVID-19 develop end-stage pulmonary fibrosis for which lung transplantation may be the only treatment.

10.1126/scitranslmed.abe4282 article EN cc-by Science Translational Medicine 2020-12-01

Rationale: Current guidelines recommend patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia receive empirical antibiotics for suspected bacterial superinfection on the basis of weak evidence. Rates ventilator-associated (VAP) in clinical trials SARS-CoV-2 are unexpectedly low. Objectives: We conducted an observational single-center study to determine prevalence and etiology at time initial intubation incidence subsequent VAP pneumonia. Methods: Bronchoscopic...

10.1164/rccm.202106-1354oc article EN cc-by-nc-nd American Journal of Respiratory and Critical Care Medicine 2021-08-19

Lung transplantation is a potentially lifesaving treatment for patients who are critically ill due to COVID-19-associated acute respiratory distress syndrome (ARDS), but there limited information about the long-term outcome.

10.1001/jama.2022.0204 article EN JAMA 2022-01-27

Veno-venous extracorporeal membrane oxygenation (V-V ECMO) support is increasingly used in the management of COVID-19-related acute respiratory distress syndrome (ARDS). However, clinical decision-making to initiate V-V ECMO for severe COVID-19 still remains unclear. In order determine optimal timing and patient selection, we investigated outcomes both non-COVID-19 patients undergoing support.

10.1111/aor.14090 article EN Artificial Organs 2021-10-25

ABSTRACT Lung transplantation can potentially be a life-saving treatment for patients with non-resolving COVID-19 acute respiratory distress syndrome. Concerns limiting transplant include recurrence of SARS-CoV-2 infection in the allograft, technical challenges imposed by viral-mediated injury to native lung, and potential risk allograft pathogens associated ventilator-induced pneumonia lung. Additionally, lung might recover, resulting long-term outcomes preferable transplant. Here, we...

10.1101/2020.10.26.20218636 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2020-10-27

There have been over 177 million cases of COVID-19 worldwide, many whom could be organ donors. Concomitantly, there is an anticipated increase in the need for donor lungs due to expanding indications. Given that respiratory tract most commonly affected by COVID-19, urgent develop assessment criteria while demonstrating safety and "efficacy" lung donation following infection. Accordingly, we report intentional transplant using from a with recent, microbiologically confirmed, infection into...

10.1111/ajt.16777 article EN cc-by-nc-nd American Journal of Transplantation 2021-07-31

Blood stream infection (BSI) is a potentially lethal complication in patients receiving extracorporeal membrane oxygenation (ECMO). It may be particularly common with veno-venous ECMO due to their long hospitalization the intensive care unit. Given that these have concurrent indwelling central venous catheters (CVC), it unclear whether circuit, CVC, or both, contribute BSI. This study evaluated risk factors associated BSI single institution of 61 from 2016 through 2019. All and circuit...

10.1097/mat.0000000000001575 article EN ASAIO Journal 2021-10-01

OBJECTIVES: Benign gastro-oesophageal anastomotic strictures after oesophagectomy can occur in up to 42% of patients. Traditional management includes serial dilations. We report our initial experience with the use a dual-anchor, lumen-apposing endoluminal stent for recurrent oesophagectomy. METHODS: Retrospective review patients who underwent ‘off label’ placement dual-anchor strictures. indications and short-term outcomes. RESULTS: placed four self-expanding stents from January July 2015....

10.1093/ejcts/ezw283 article EN European Journal of Cardio-Thoracic Surgery 2016-09-15

Background Long-term nasogastric tubes are uncomfortable and associated with complications such as impairment speech swallowing, septum trauma, epistaxis, alar necrosis, intubation of the trachea among others. Pharyngostomy (PTs) an alternative for prolonged enteral feeding, transluminal drainage collections, gastric decompression in patients intestinal obstruction inoperable abdomen. Patients Methods This is a retrospective analysis who had PT placed at our institution from May 2005 to...

10.1055/s-0036-1593878 article EN The Thoracic and Cardiovascular Surgeon 2016-11-17

Rationale: Coronavirus disease 2019 (COVID-19) can cause severe respiratory failure that worsens despite maximal medical management. When to initiate extracorporeal membrane oxygenation (ECMO) and how manage these patients on ECMO is not clear. Here, we present our experience with venovenous support COVID-19 compare it historic supported VV-ECMO for other causes of failure. Methods: Patients admitted tertiary academic center in 2020 who received VV were included this retrospective chart...

10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2498 article EN 2021-05-01
Coming Soon ...