A5073827693- Urticaria and Related Conditions
- Contact Dermatitis and Allergies
- Drug-Induced Adverse Reactions
- Shoulder and Clavicle Injuries
- melanin and skin pigmentation
- Neuroscience and Neuropharmacology Research
- Shoulder Injury and Treatment
- Mast cells and histamine
- Skin Protection and Aging
- Nail Diseases and Treatments
- Neurotransmitter Receptor Influence on Behavior
- Bipolar Disorder and Treatment
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Nerve Injury and Rehabilitation
- Erythropoietin and Anemia Treatment
- Cardiac electrophysiology and arrhythmias
- Autoimmune Bullous Skin Diseases
- Advanced Neuroimaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Cardiovascular Effects of Exercise
- Hair Growth and Disorders
- Biomedical Research and Pathophysiology
- Skin and Cellular Biology Research
- Neural Networks and Reservoir Computing
- MRI in cancer diagnosis
Nagoya City University Hospital
2024
Mizuho (Japan)
2024
Kansai Medical University
2017-2022
Sapporo Medical University
2019-2022
Keiyu Orthopedic Hospital
2022
Astellas Pharma (Japan)
2016-2020
Yokohama City University
1978-2017
Hyogo Prefectural Amagasaki General Medical Center
2013
Dokkyo Medical University
2010
keiyu Hospital
2000
Diffusional anisotropy of human brain was investigated clinically in six adult volunteers, eight premature neonates, and three infants aged 5-10 months. Diffusion-weighted magnetic resonance imaging performed with gradient b 450 sec/mm2. The direction diffusion-sensitive gradients changed among x, y, z axes according to the orientation neurofibers white matter. T1- T2-weighted images also were obtained for evaluation myelination. demonstrated matter adults. Extensive signal attenuation...
ABSTRACT A 64‐year‐old man with pneumococcal septic shock and subsequent renal failure underwent treatments antibiotics including intravenous vancomycin (VCM). Blistering skin lesions appeared 10 days after the initiation of VCM. When patient was transferred to us 5 months later, blisters erythema were still observed on abdomen thighs. Histopathological examination revealed subepidermal blister infiltration eosinophils neutrophils, direct immunofluorescence linear IgA deposition at basement...
Abstract Roxadustat is a hypoxia‐inducible factor prolyl hydroxylase inhibitor in late‐stage clinical development for the treatment of anemia chronic kidney disease. Spherical carbon adsorbent (SCA) used patients with disease and has been shown to impact absorption certain concomitant drugs. Two phase 1, open‐label, randomized, crossover studies were conducted healthy adult Japanese males investigate effect food SCA on pharmacokinetics single oral dose roxadustat. Subjects study received...
What is known and objective Roxadustat a hypoxia-inducible factor prolyl hydroxylase inhibitor currently being investigated for the treatment of anemia in chronic kidney disease. Lanthanum carbonate phosphate binder that commonly used to treat hyperphosphatemia patients with This study effect lanthanum on pharmacokinetics, safety tolerability single oral dose roxadustat healthy non-elderly adult male subjects. Methods was an open-label, randomized, two-period, two-sequence crossover males....
Since the late 1980s, a birnaviral gill disease has been occurring in Japanese eels Anguilla japonica reared warmwater ponds western regions Japan. Diseased mostly displayed marked formations of aneurysmal hematomas within lamellae and high mortalities. Histological examination revealed necrosis pillar cells subsequent aggregation erythrocytes inside lamellar capillaries, proliferation interlamellar epithelia onto lamellae. Gastric gland were also necrotized. Electron microscopy birnavirus...
A 73-year-old man with diabetes mellitus was referred to our department for ultraviolet treatment erythematous skin lesions itching. On dipeptidyl peptidase-4 inhibitor (DPP-4i) sitagliptin (Januvia®) mellitus, the appeared and spread whole body. At initial visit, erythema multiforme-like crusts were observed on trunk extremities, patient suspected have drug eruption. Histopathology demonstrated eosinophilic infiltration in superficial dermis inflammatory cell epidermis. Sitagliptin...
Abstract Objectives Area under the concentration–time curve (AUC)–guided dosing of vancomycin was introduced in a clinical setting; however, target range non–steady-state AUCs, such as Day 1 AUC and 2 AUC, remains controversial. Therefore, we sought to determine pharmacokinetic parameter thresholds identify independent risk factors associated with acute kidney injury (AKI) establish safe initial design for administration. Methods A single-centre, retrospective, cohort study hospitalized...
Abstract Solar urticaria has unique spectra, such as inhibition and augmentation. The clinical significance of these especially augmentation, is not well understood. Reported cases solar with augmentation spectra are extremely rare in the published English‐language work. purposes this study were to evaluate features elucidate mechanisms importance spectra. We experienced 11 (five females, six males; mean age, 40.1 years; range, 1–74) from April 2007 July 2019. Augmentation UV‐B three cases,...
Paraneoplastic pemphigus (PNP) is an autoimmune mucocutaneous disease associated with lymphoproliferative neoplasms. We report a case of PNP Castleman's disease. A 39-year-old man showed white lesions on both edges the tongue. The were diagnosed as lichen planus, compatible basis clinical features and histopathological examination. patient was treated steroid ointment azulene gargle for 1 year. However, after mild common cold symptoms, he presented extensive ulceration erosions throughout...