A5101415426- Soil Carbon and Nitrogen Dynamics
- Immune cells in cancer
- Immune Cell Function and Interaction
- Viral Infections and Immunology Research
- Ecology and Vegetation Dynamics Studies
- Animal Disease Management and Epidemiology
- Plant Water Relations and Carbon Dynamics
- Remote Sensing in Agriculture
- Tea Polyphenols and Effects
- Fermentation and Sensory Analysis
- Plant Stress Responses and Tolerance
- Plant Gene Expression Analysis
- Soil and Water Nutrient Dynamics
- Peatlands and Wetlands Ecology
- Chromatography in Natural Products
- Sparse and Compressive Sensing Techniques
- Cassava research and cyanide
- Advanced biosensing and bioanalysis techniques
- interferon and immune responses
- Advanced Measurement and Detection Methods
- Remote Sensing and Land Use
- Music and Audio Processing
- Text and Document Classification Technologies
- RNA Research and Splicing
- Plant Molecular Biology Research
Tobacco Research Institute
2020-2025
Chinese Academy of Agricultural Sciences
2018-2025
Peking University People's Hospital
2017-2025
Peking University
2007-2025
Inner Mongolia Academy of Agricultural & Animal Husbandry Sciences
2022-2025
Beijing Chest Hospital
2018-2025
Nanjing Agricultural University
2022-2025
Nanjing Medical University
2025
Jiangsu Province Hospital
2025
Ministry of Agriculture and Rural Affairs
2024
Ewing's sarcoma (EwS), a common pediatric bone cancer, is associated with poor survival due to lack of therapeutic targets for immunotherapy or targeted therapy. Therefore, more effective treatment options are urgently needed. Since novel immunotherapies may address this need, we performed an integrative analysis involving single-cell RNA sequencing, cell function experiments, and humanized models dissect the immunoregulatory interactions in EwS identify strategies optimizing...
Elucidating the variation of allocation pattern ecosystem net primary productivity (NPP) and its underlying mechanisms is critically important for understanding changes aboveground belowground functions. Under optimal partitioning theory, plants should allocate more NPP to organ that acquires most limiting resource, this expectation has been widely used explain predict under changing precipitation. However, confirmatory evidence theory mostly come from observed spatial in relationship...
Abstract Background Cervical cancer (CC) is the fourth most common in women worldwide. Although immunotherapy has been applied clinical practice, its therapeutic efficacy remains far from satisfactory, necessitating further investigation of mechanism CC immune remodeling and exploration novel treatment targets. This study aimed to investigate explore potential Methods We conducted single‐cell RNA sequencing on a total 17 specimens, including normal cervical tissues, high‐grade squamous...
Realizing controllable input of botanical pesticides is conducive to improving pesticide utilization, reducing residues, and avoiding environmental pollution but extremely challenging. Herein, we constructed a smart pesticide-controlled release platform (namely, SCRP) for enhanced treatment tobacco black shank based on encapsulating honokiol (HON) with mesoporous hollow structured silica nanospheres covered pectin chitosan oligosaccharide (COS). The SCRP has loading capacity 12.64% HON could...
Abstract Key message HanMYB1 was found to play positive roles in the modulation of anthocyanins metabolism based on integrative analysis different color cultivars and related molecular genetic analyses. As a high value ornamental edible crop with various colors, sunflowers ( Helianthus annuus L.) provide an ideal system understand formation flower color. Anthocyanins are major pigments higher plants, which is associated development colors ability oxidation resistance. Here, we performed...
Arbuscular mycorrhizal fungi (AMF) are critical links in plant-soil continuum and play a role soil carbon cycles. Soil respiration, one of the largest fluxes global cycle, is sensitive to precipitation change semiarid ecosystems. In this study, field experiment with fungicide application water addition was conducted during 2010-2013 steppe Inner Mongolia, China, respiration continuously measured investigate influences AMF on under different regimes. Results showed that promoted by treatment...
Label distribution learning (LDL) is a novel machine paradigm to deal with label ambiguity issues by placing more emphasis on how relevant each particular instance. Many LDL algorithms have been proposed and most of them concentrate the models, while few focus feature selection problem. All existing models are built simple space in which all features shared class labels. However, this kind traditional data representation strategy tends select that distinguishable for labels, but ignores...
Abstract Apocynum venetum L. is a traditional Chinese medicinal herb with great potential to treat angiocardiopathy. Its major constituents are flavonoids. However, the natural habitats of A. typically affected by salt stress, which can modify both biomass and accumulation compounds. In this study, effects stress on growth development , flavonoids expression patterns genes involved in flavonoid biosynthesis were evaluated. general, seedlings (seedling height, root length, leaf width seed...
Osteosarcoma is one of the most aggressive malignant bone tumors worldwide. Although great advancements have been made in its treatment owing to advent neoadjuvant chemotherapy, problem lung metastasis a major obstacle improvement survival outcomes. Thus, aim present study screen novel and key biomarkers, which may act as potential prognostic markers therapeutic targets osteosarcoma. We utilized Robust Rank Aggregation (RRA) method integrate three osteosarcoma microarray datasets downloaded...
The Chishui River basin is the main production area of sauce-flavor Baijiu. Due to particularity Baijiu technology, a large site workshops needs be built for brewing and storage. Therefore, used natural karst caves Guizhou province manufacture Baijiu, which has enriched connotation saved valuable land resources. In this study, fermentation grains in seven stages during Xiasha round cave-brewed (CBSB) were detected using combination physicochemical analysis, Headspace solid-phase...
The natural cave located on the bank of Chishui River in Guizhou is currently only base country for brewing sauce-flavor Baijiu cave. Utilizing not enriches microbial source Baijiu, but also helps conserving land resources. This article studied communities and flavor compounds fermented grains environmental microorganisms during first second rounds heap fermentation cave-brewed (CBSB). results indicated that Thermomyces, Torulaspora, Thermoascus were dominant fungal genera fermentation,...
Graph convolutional networks (GCNs) have achieved remarkable performance on skeleton-based action recognition. Existing GCN-based methods usually apply the fixed graph topology and one temporal convolution kernel to extract spatial features of joints features, which is from a single-scale perspective. Actually, human actions are coordinated by various body parts in domain, exhibit different characteristics domain. Therefore, it appropriate model multi-scale information that can enhance both...
Label distribution learning (LDL) can be viewed as the generalization of multi-label learning. This novel paradigm focuses on relative importance different labels to a particular instance. Most previous LDL methods either ignore correlation among labels, or only exploit label correlations in global way. In this paper, we utilize both and local relevance provide more information for training model propose algorithm. particular, matrix based low-rank approximation is applied capture...
Abstract Trait‐based approaches are key to develop mechanistic understanding of differences in plant species performance under environmental change. While mean trait values have been widely used link functional traits performance, the contribution intraspecific variation and plasticity remains unclear. Moreover, environmentally induced changes biomass caused by number individuals individual growth rate, both which should be influenced plasticity. Our goal this study is use trait‐based...
Foot-and-mouth disease virus (FMDV) is an important pathogen that affects livestock breeding and causes huge economic losses worldwide. Currently, the development of antiviral agents to combat FMDV infection at early stages being explored. As viral replication critically depends on host for nucleoside supply, enzymes involved in nucleotides biosynthesis may represent potential targets agents. In present study, effects IMP dehydrogenase (AVN-944 mycophenolate mofetil) dihydroorotate...
Salt stress is a serious abiotic that primarily inhibits plant growth, resulting in severe yield losses. Our previous research found flavonoids play important roles A. venetum salt tolerance. In response to stress, we noted the flavonoid content was depleted venetum. However, detailed mechanism still not clear. this study, expression patterns of three synthetase genes, AvF3H, AvF3'H, and AvFLS were systemically analyzed under seedlings. The tolerance transgenic Arabidopsis plants improved by...