Fatma Şen

ORCID: 0000-0003-4983-1190
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About
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Research Areas
  • Lung Cancer Treatments and Mutations
  • Lung Cancer Research Studies
  • Breast Cancer Treatment Studies
  • Medical Imaging Techniques and Applications
  • Lung Cancer Diagnosis and Treatment
  • Advanced Breast Cancer Therapies
  • Renal cell carcinoma treatment
  • HER2/EGFR in Cancer Research
  • Pancreatic and Hepatic Oncology Research
  • Venous Thromboembolism Diagnosis and Management
  • Lymphoma Diagnosis and Treatment
  • Gastric Cancer Management and Outcomes
  • Radiomics and Machine Learning in Medical Imaging
  • Ovarian cancer diagnosis and treatment
  • Metastasis and carcinoma case studies
  • Growth Hormone and Insulin-like Growth Factors
  • Cancer Treatment and Pharmacology
  • Testicular diseases and treatments
  • Colorectal Cancer Treatments and Studies
  • Breast Lesions and Carcinomas
  • Cancer and Skin Lesions
  • Cutaneous Melanoma Detection and Management
  • Viral-associated cancers and disorders
  • Lipid metabolism and disorders
  • Neuroendocrine Tumor Research Advances

University of California, Davis
2021-2025

Avrasya University
2018-2024

California State University, Sacramento
2023

Imaging Center
2023

Hacettepe University
2023

University of California Davis Medical Center
2023

Yüksek İhtisas Üniversitesi
2022

Istanbul University
2009-2019

Acıbadem University
2016

Hitit Üniversitesi
2013-2014

Background: The use of antracycline (ANT) in breast cancer has been associated with adverse cardiac events. Two-dimensional (2D) strain imaging (SI) can provide a more sensitive measure altered left ventricular (LV) systolic function. We aimed to evaluate the preventive effect carvedilol administration assessed by SI patient treated ANT. Methods: Patients receiving ANT were randomly assigned carvedilol- or placebo-receiving group. Each received an echocardiographic examination conventional...

10.5603/cj.a2013.0150 article EN Cardiology Journal 2013-10-21

With most of the T cells residing in tissue, not blood, developing noninvasive methods for vivo quantification their biodistribution and kinetics is important studying role immune response memory. This study presents first use dynamic positron emission tomography (PET) kinetic modeling measurement CD8

10.1126/sciadv.adh7968 article EN cc-by-nc Science Advances 2023-10-12

Metaplastic breast carcinoma (MBC) differs from classic invasive ductal carcinomas regarding incidence, pathogenesis, and prognosis. The purpose of this study was to compare patients with MBC clinicopathologic treatment-matched triple-negative (TNBC) in terms response treatment, progression, survival. Fifty-four 51 TNBC, who were treated at Istanbul University, Institute Oncology, between 1993 2014, included the study. After correctly matching 1 2 groups, they compared determine differences...

10.1097/md.0000000000002341 article EN cc-by-nc Medicine 2015-12-01

Pancreatic cancer is a major health concern worldwide and, despite the attempts at management, prognosis of patients with metastatic pancreatic remains poor, median survival few months. The aim this study was to identify and evaluate clinicopathological factors elucidate clinical significance patient age for outcome cancer. Data from total 154 histologically confirmed diagnosis cancer, who were treated followed‑up in our clinic, recorded medical charts. sample included 102 (66%) males 58...

10.3892/mco.2013.131 article EN Molecular and Clinical Oncology 2013-05-23

<i>Objective:</i> Compared to the cutaneous melanoma, noncutaneous melanomas are relatively rare and have a distinct pattern of behavior. We performed this study define clinical characteristics outcomes patients with emphasize how they differ from melanomas. <i>Methods:</i> 216 who were diagnosed melanoma assessed their medical records between 2000 2010 retrieved cancer registry. 475 used for comparison. <i>Results:</i> Of patients, 83 had mucosal 101...

10.1159/000334863 article EN Oncology 2011-01-01

The aim of this study is to determine whether renin-angiotensin system blockers (RASBs), which include angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin-2 receptor 1 (ARBs), improve the overall survival (OS) patients with metastatic non-small cell lung cancer (NSCLC). medical charts 117 NSCLC were retrospectively assessed. Thirty-seven (RASB group) using RASBs during systemic treatment compared 80 controls (control who did not use following diagnosis NSCLC. histological tumor...

10.1097/md.0000000000000887 article EN cc-by-nc Medicine 2015-06-01

<h3>Objective</h3> Epithelial ovarian cancer (EOC) is the leading cause of death among gynecological tumors and usually diagnosed at advanced stage. We aimed to identify clinical prognostic relevance coagulation tests their correlation with serum CA-125 levels in EOC. <h3>Materials Methods</h3> A total 33 advanced-stage (stages III IV) EOC patients were enrolled study. Of these patients, 17 had received neoadjuvant chemotherapy 16 after optimal debulking surgery. Several clinicopathologic...

10.1097/igc.0b013e31827b8796 article EN cc-by-nc-nd International Journal of Gynecological Cancer 2012-12-22

High BMI is a well-known risk factor for the development and recurrence of several solid tumours, including CRC. Obesity associated with increased levels vascular endothelial growth (VEGF). Bevacizumab main targeted therapy inhibiting tumour angiogenesis by blocking VEGF/VEGF receptor pathway. Elevated VEGF in obese patients might provoke resistance to anti-VEGF therapy. We evaluated efficacy bevacizumab on TTP among mCRC through stratifying them according their BMI. Patients who had been...

10.1007/s12032-013-0679-4 article EN cc-by Medical Oncology 2013-08-06

The aim of this study is to evaluate the correlation coagulation tests with various clinicopathological variables and tumor markers among colorectal cancer (CRC) patients.Ninety-four CRC patients were included for evaluation factors, assays marker levels.Metastatic disease was related elevated INR (p= 0.03). Stage III had higher D-dimer values compared stage II Correlation indicated a tendency towards levels CEA than median 0.01). High CA 19-9 also associated 0.007). Elderly age, distant...

10.3233/cbm-150477 article EN Cancer Biomarkers 2015-06-02

Abstract Background Total-body positron emission tomography/computed tomography (PET/CT) scanners are characterized by higher signal collection efficiency and greater spatial resolution compared to conventional scanners, allowing for delayed imaging improved image quality. These advantages may also lead better detection of physiological processes that diagnostic professionals should be aware of. The gallbladder (GB) is not usually visualized as an 18 F-2-fluorodeoxyglucose ( F-FDG)-avid...

10.1186/s12880-022-00957-5 article EN cc-by BMC Medical Imaging 2023-01-10

ÖZETGiriş: Myokard infarktüsü (Mİ), akut stres bozukluğu (ASB), travma sonrası (TSSB) veya ikisinin birlikte gelişmesine yol açabilen, tekrarlama olasılığı yüksek ve kronik yeti yitim kaybı yapabilen, hayatı tehdit eden bir olaydır

10.4274/npa.y6394 article TR Nöro Psikiyatri Arşivi 2014-06-05

With the majority of CD8+ T cells residing and functioning in tissue, not blood, developing noninvasive methods for vivo quantification their biodistribution kinetics humans offers means studying key role adaptive immune response memory. This study is first report on using positron emission tomography (PET) dynamic imaging compartmental kinetic modeling measurement whole-body human subjects. For this, a 89Zr-labeled minibody with high affinity CD8 (89Zr-Df-Crefmirlimab) was used total-body...

10.1101/2023.03.14.23287121 preprint EN cc-by-nd medRxiv (Cold Spring Harbor Laboratory) 2023-03-20

Abstract Background Classic Kaposi’s sarcoma (CKS) affects an elderly population; it is important to have effective treatment options with high activity and relatively low toxicity, availability be used for long periods. Objective We investigated the safety of single‐agent etoposide oral administration schedule in patients advanced CKS. Methods Histologically confirmed, CKS were eligible study. All had a negative test HIV good performance status. received 50 mg twice daily 10 days every 3...

10.1111/j.1468-3083.2011.04404.x article EN Journal of the European Academy of Dermatology and Venereology 2011-12-20

Little is known about the mechanism of desensitization in hypersensitivity drug reactions.The aim this study was to evaluate effects on some cytokine levels patients desensitized for reactions.Patients with a reaction any whom planned culprit drug, who could tolerate same drugs and healthy subjects were not exposed these enrolled. Bead-based Milliplex MAP multiplex technology used determine interleukin (IL)-4, IL-5, interferon-γ IL-10 sera as baseline 24 hours after had been completed...

10.5415/apallergy.2019.9.e9 article EN cc-by-nc Asia Pacific Allergy 2019-01-01
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