A5047579260- Immune cells in cancer
- Advanced MEMS and NEMS Technologies
- Immune responses and vaccinations
- Mathematical and Theoretical Epidemiology and Ecology Models
- Microfluidic and Capillary Electrophoresis Applications
- Advanced Mathematical Modeling in Engineering
- Immune Response and Inflammation
- Vehicle emissions and performance
- Neuroinflammation and Neurodegeneration Mechanisms
- Kruppel-like factors research
- Nanopore and Nanochannel Transport Studies
- Phagocytosis and Immune Regulation
- Air Quality Monitoring and Forecasting
- Graphene and Nanomaterials Applications
- Recycling and Waste Management Techniques
- Sleep and Wakefulness Research
- Thin-Film Transistor Technologies
- Barrier Structure and Function Studies
- Wnt/β-catenin signaling in development and cancer
- Cell Adhesion Molecules Research
- Nanowire Synthesis and Applications
- Cancer, Hypoxia, and Metabolism
- Ubiquitin and proteasome pathways
- Hemoglobin structure and function
- Cell death mechanisms and regulation
Illinois College
2022-2024
Hubei University of Chinese Medicine
2023
University of Illinois Chicago
2022-2023
University of Illinois Urbana-Champaign
2022
Guangdong University of Technology
2022
Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
2022
Macau University of Science and Technology
2022
Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai)
2022
Illinois Institute of Technology
2018-2020
Recent studies suggest that training of innate immune cells such as tissue-resident macrophages by repeated noxious stimuli can heighten host defense responses. However, it remains unclear whether trained immunity also enhances injury resolution to counterbalance the heightened inflammatory Here, we studied lung-resident alveolar (AMs) prechallenged with either bacterial endotoxin or Pseudomonas aeruginosa and observed these AMs showed greater resilience pathogen-induced cell death....
Cancers are caused by mutations to genes that regulate cell normal functions. The capability rapid and reliable detection of specific target gene variations can facilitate early disease diagnosis also enables personalized treatment cancer. Most the currently available methods for DNA mutation time-consuming and/or require use labels or sophisticated instruments. In this work, we reported a label-free enzymatic reaction-based nanopore sensing strategy detect mutations, including base...
Microplastic pollution is a global problem that has attracted extensive attention and become very hot topic in the scientific community [...]
Sleep deprivation impairs learning and memory. The neuroprotective function of ginsenoside Rg1 (Rg1) has been reported. This study aimed to investigate the alleviative effect underlying mechanism action on memory deficits induced by sleep deprivation. Using 72 h LED light establish model treatment with Rg1-L (0.5 mg/ml), Rg1-H (1 melatonin (positive control, 0.25 we investigated behavioral performance zebrafish through 24 autonomous movement tracking, a novel tank diving test, T-maze test....
A common MEMS micro-bridge structure-based process was developed on 200 mm standard CMOS Al back end of line. Thick amorphous-Si (alpha-Si) film and used as the sacrificial material with well-controlled stress to improve wafer warpage. Anchor/contact structure formed by a trench first scheme no metal or dielectric plug in it, thin Ti/TiN bilayer barrier an electrode layer define sensing resistor improved step coverage anchor sidewall. wet etching introduced for patterning almost damage...
Mitochondrial fusion and fission are dynamic processes regulated by the cellular microenvironment. Under nutrient starvation conditions, mitochondrial is strengthened for energy conservation. We have previously shown that newborns of Ubl4A-deficient mice were more sensitive to stress with a higher rate mortality than their wild-type littermates. Ubl4A binds actin-related protein Arp2/3 complex synergize actin branching process. Here, we showed deficiency in resulted fragmentation apoptosis....
ABSTRACT Dysfunction of the blood-brain barrier (BBB) is emerging as a critical mediator Alzheimer’s Disease (AD) progression and precedes formation large Amyloid-β (Aβ) plaques in AD patients. Maintenance blood brain integrity by microvascular endothelial cells (BMECs) essential for homeostasis part maintained WNT/β-catenin signaling. We hypothesized that Aβ induces dysfunction inhibiting WNT/β- catenin signaling cells, leading to reduced expression BBB-related genes function. In we found...
<abstract><p>In this paper, we study a free boundary problem for vascularized tumor growth with time delay in the process of regulating apoptosis. The characteristic model is that both vascularization and apoptosis regulation considered. In mathematical form, expressed as Robin boundary. We prove existence uniqueness global solution their asymptotic behavior. effects parameters on are discussed. Depending importance rate, will tend to unique steady state or eventually disappear....
Abstract Given their ancient evolutionary origins, eukaryotic mitochondria possess multiple vestiges of prokaryotic ancestors. One such factor is the N-terminal formylation proteins encoded by mitochondrial DNA. N-formylated are also released bacteria and trigger activation immune cells as neutrophils. Growing evidence indicate that circulating levels formyl elevated in serum patients with excessive inflammatory responses neutrophil like bacterial counterparts. However, cellular source these...
Abstract Endothelial adherens junctions (AJs) are critical for the regulation of vascular barrier integrity and undergo dis-assembly during inflammatory injury, thus causing leakiness. AJ re-assembly is necessary restoration endothelial following initial injury. Here we examine metabolic underpinnings that drive integrity. In response to stimuli, glycolysis regulatory enzyme PFKFB3 activated, resulting in a rapid sustained increase intracellular glycolytic ATP, especially proximity AJs at...
A dog gets abandoned on the side of road. Attached to a street light, he stays alone until day meets young astronaut wannabe and professional cyclist who keeps trying beat her highest score.