A5082430535- Tissue Engineering and Regenerative Medicine
- Electrospun Nanofibers in Biomedical Applications
- Immune cells in cancer
- Phagocytosis and Immune Regulation
- Glaucoma and retinal disorders
- Urological Disorders and Treatments
- Immune responses and vaccinations
- Retinal Imaging and Analysis
- Retinal Diseases and Treatments
University of Illinois Chicago
2022-2024
Recent studies suggest that training of innate immune cells such as tissue-resident macrophages by repeated noxious stimuli can heighten host defense responses. However, it remains unclear whether trained immunity also enhances injury resolution to counterbalance the heightened inflammatory Here, we studied lung-resident alveolar (AMs) prechallenged with either bacterial endotoxin or Pseudomonas aeruginosa and observed these AMs showed greater resilience pathogen-induced cell death....
Abstract To date, there are no efficacious translational solutions for end-stage urinary bladder dysfunction. Current surgical strategies, including diversion and augmentation enterocystoplasty (BAE), utilize autologous intestinal segments (e.g. ileum) to increase capacity protect renal function. Considered the standard of care, BAE is fraught with numerous short- long-term clinical complications. Previous trials employing tissue engineering approaches regeneration have also been unable...