A5035737078- Prostate Cancer Diagnosis and Treatment
- Nanoparticle-Based Drug Delivery
- Prostate Cancer Treatment and Research
- Urological Disorders and Treatments
- Genital Health and Disease
- Urologic and reproductive health conditions
- Ethics and Legal Issues in Pediatric Healthcare
- Urinary Bladder and Prostate Research
- Nanoplatforms for cancer theranostics
- Sexual function and dysfunction studies
- Radiopharmaceutical Chemistry and Applications
- Pediatric Urology and Nephrology Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Advanced Nanomaterials in Catalysis
- Healthcare Policy and Management
- Renal cell carcinoma treatment
- Mechanisms of cancer metastasis
- Medical Imaging Techniques and Applications
- Ethics in Clinical Research
- Healthcare cost, quality, practices
- Hormonal and reproductive studies
- Bladder and Urothelial Cancer Treatments
- Male Reproductive Health Studies
- Nanoparticles: synthesis and applications
- Testicular diseases and treatments
University of North Carolina at Chapel Hill
2022-2025
Lurie Children's Hospital
2021-2024
Cleveland Clinic
2014-2019
Cleveland Clinic Lerner College of Medicine
2017
Ohio Gastroenterology and Liver Institute
2016
Northwestern University
2009-2014
Argonne National Laboratory
2011
Chinese Academy of Sciences
2011
Ningbo Institute of Industrial Technology
2011
Center for Cancer Research
2004-2006
While few publications have documented the uptake of nanoparticles in plants, this is first study describing and distribution ultrasmall anatase TiO2 plant model system Arabidopsis. We modified nanoparticle surface with Alizarin red S sucrose demonstrated that nanoconjugates traversed cell walls, entered into cells, accumulated specific subcellular locations. Optical X-ray fluorescence microscopy coregistered vacuoles nuclei.
Abstract Resistance to anthracyclines and other chemotherapeutics due P-glycoprotein (pgp)-mediated export is a frequent problem in cancer treatment. Here, we report that iron oxide–titanium dioxide core-shell nanocomposites can serve as efficient carriers for doxorubicin overcome this common mechanism of drug resistance cells. Doxorubicin nanocarriers (DNC) increased effective uptake drug-resistant ovarian Mechanistically, bound the TiO2 surface by labile bond was severed upon acidification...
Abstract To date, there are no efficacious translational solutions for end-stage urinary bladder dysfunction. Current surgical strategies, including diversion and augmentation enterocystoplasty (BAE), utilize autologous intestinal segments (e.g. ileum) to increase capacity protect renal function. Considered the standard of care, BAE is fraught with numerous short- long-term clinical complications. Previous trials employing tissue engineering approaches regeneration have also been unable...
No AccessJournal of UrologyAdult Urology1 Sep 2017Intermediate-Term Outcomes for Men with Very Low/Low and Intermediate/High Risk Prostate Cancer Managed by Active Surveillance Yaw A. Nyame, Nima Almassi, Samuel C. Haywood, Daniel J. Greene, Vishnu Ganesan, Charles Dai, Joseph Zabell, Chad Reichard, Hans Arora, Anna Zampini, Alice Crane, Hettel, Ahmed Elshafei, Khaled Fareed, Robert Stein, Ryan K. Berglund, Michael Gong, Stephen Jones, Eric Klein, Andrew Stephenson NyameYaw Nyame ,...
No AccessJournal of UrologyPediatric Urology1 Feb 2022Safety and Efficacy Robot-Assisted Laparoscopic Pyeloplasty Compared to Open Repair in Infants under 1 Year AgeThis article is commented on by the following:Editorial CommentEditorial Comment James T. Rague, Hans C. Arora, David I. Chu, Rachel Shannon, Ilina Rosoklija, Emilie K. Johnson, Edward M. Gong, Bruce W. Lindgren RagueJames Rague Division Urology, Ann Robert H. Lurie Children's Hospital Chicago, Illinois , AroraHans Arora ChuDavid...
Background: The purpose of this study was to develop a candidate symptom index for men with an established diagnosis chronic orchialgia. Methods: Based on interviews patients and providers, we developed 70-item questionnaire that focused seven areas orchialgia symptoms: pain, location, urinary symptoms, sexual dysfunction, medical history quality life (QOL) impact. completed by at two centers. Cluster analysis performed the software package R (3.2.1). Results: A total 113 survey. Median...
We determined the effect of 5α-reductase inhibitors on disease reclassification in men with prostate cancer optimally selected for active surveillance.In this retrospective review we identified 635 patients surveillance between 2002 and 2015. Patients favorable features repeat biopsy, defined as absent Gleason upgrading, were included cohort. stratified by those who did or not receive finasteride dutasteride within 1 year diagnosis. The primary end point was grade reclassification, any...
Germline PTEN mutations defining hamartoma tumor syndrome (PHTS) confer heritable predisposition to breast, endometrial, thyroid and other cancers with known age-related risks, but it remains impossible predict if any individual will develop cancer. In the general population, gut microbial dysbiosis has been linked cancer, yet is unclear whether these are associated in PHTS patients. this pilot study, we aimed characterize composition of stool, urine, oral wash from 32 mutation-positive...
Currently no data exist to guide renal surgeons on the perioperative use of renin-angiotensin blockers despite potential cardiorenal benefits. We aimed assess impact resuming postoperative function and adverse cardiac events following partial nephrectomy.This is an observational analysis patients who underwent robot-assisted laparoscopic nephrectomy from 2006 2014 at a single institution. The Wilcoxon rank sum chi-square tests, logistic regression were used risk stratified by history pattern...