Yvonne Y. Chan

ORCID: 0000-0002-5869-6042
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About
Contact & Profiles
Research Areas
  • Urological Disorders and Treatments
  • Bladder and Urothelial Cancer Treatments
  • Pediatric Urology and Nephrology Studies
  • Tissue Engineering and Regenerative Medicine
  • Cardiac, Anesthesia and Surgical Outcomes
  • Urinary Bladder and Prostate Research
  • Urinary and Genital Oncology Studies
  • Spinal Dysraphism and Malformations
  • Renal cell carcinoma treatment
  • Electrospun Nanofibers in Biomedical Applications
  • Hormonal and reproductive studies
  • Enhanced Recovery After Surgery
  • Cancer Genomics and Diagnostics
  • Anesthesia and Sedative Agents
  • Urinary Tract Infections Management
  • Sexual function and dysfunction studies
  • Renal and related cancers
  • Sexual Differentiation and Disorders
  • Hernia repair and management
  • Ureteral procedures and complications
  • Anesthesia and Neurotoxicity Research
  • Cerebrospinal fluid and hydrocephalus
  • Simulation-Based Education in Healthcare
  • Estrogen and related hormone effects
  • Restraint-Related Deaths

University of California, Davis
2016-2025

The University of Texas Southwestern Medical Center
2020-2024

Children's Medical Center
2023-2024

Lurie Children's Hospital
2020-2022

Southwestern Medical Center
2020-2022

Changi General Hospital
2021

Chinese University of Hong Kong
2021

Prince of Wales Hospital
2021

Northwestern University
2020-2021

UC Davis Children's Hospital
2016-2018

Abstract To date, there are no efficacious translational solutions for end-stage urinary bladder dysfunction. Current surgical strategies, including diversion and augmentation enterocystoplasty (BAE), utilize autologous intestinal segments (e.g. ileum) to increase capacity protect renal function. Considered the standard of care, BAE is fraught with numerous short- long-term clinical complications. Previous trials employing tissue engineering approaches regeneration have also been unable...

10.1093/pnasnexus/pgae038 article EN cc-by-nc-nd PNAS Nexus 2024-01-30

Adenovirus small e1a oncoprotein causes ∼70% reduction in cellular levels of histone H3 lysine 18 acetylation (H3K18ac). It is unclear, however, where this dramatic occurs genome-wide. ChIP-sequencing revealed that by 24 h after expression, erases 95% H3K18ac peaks normal, contact-inhibited fibroblasts and replaces them with one-third as many at new genomic locations. The promoters intergenic regions genes fibroblast-related functions are eliminated infection, established highly induced...

10.1101/gr.132308.111 article EN cc-by-nc Genome Research 2012-04-12

Abstract Complications associated with urinary bladder augmentation provide the motivation to delineate alternative tissue regenerative engineering strategies. We describe results of varying proportion bone marrow (BM) mesenchymal stem cells (MSCs) CD34 + hematopoietic stem/progenitor (HSPCs) co-seeded onto synthetic POC [poly(1,8 octamethylene citrate)] or small intestinal submucosa (SIS) scaffolds and their contribution regeneration. Human BM MSCs HSPCs were SIS at cell ratios 50 K...

10.1038/s41598-021-81939-5 article EN cc-by Scientific Reports 2021-01-27

Pyogenic granuloma, also known as lobular capillary hemangioma, is a benign vascular tumor rarely found in the genitourinary tract. Here, we present case of 6-year-old boy presenting with gross hematuria who was to have mass at bladder base on ultrasound. Endoscopic resection performed, revealing originating from prostatic urethra. Pathology pyogenic granuloma. This entity has not previously been reported arise pediatric urethra and should be considered differential for children those or...

10.1016/j.eucr.2022.102264 article EN cc-by-nc-nd Urology Case Reports 2022-10-19
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