Shailendra Kumar Mishra

ORCID: 0000-0003-4996-978X
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About
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Research Areas
  • Genetic and phenotypic traits in livestock
  • Cancer-related molecular mechanisms research
  • Animal Nutrition and Physiology
  • Genetic Mapping and Diversity in Plants and Animals
  • T-cell and B-cell Immunology
  • MicroRNA in disease regulation
  • Animal Disease Management and Epidemiology
  • Silkworms and Sericulture Research
  • Microbial infections and disease research
  • Gut microbiota and health
  • Livestock and Poultry Management
  • Livestock Farming and Management
  • Parasitic Diseases Research and Treatment
  • Clostridium difficile and Clostridium perfringens research
  • Immune Cell Function and Interaction
  • Reproductive tract infections research
  • T-cell and Retrovirus Studies
  • Animal Genetics and Reproduction
  • Immune Response and Inflammation
  • Vaccine Coverage and Hesitancy
  • Peroxisome Proliferator-Activated Receptors
  • Biochemical Analysis and Sensing Techniques
  • Agricultural Economics and Practices
  • Insects and Parasite Interactions
  • Heat shock proteins research

REVA University
2024

Nepal Sanskrit University
2023

Tribhuvan University
2023

Institute of Engineering
2023

National Bureau of Animal Genetic Resources
2014-2023

Indian Council of Medical Research
1974-2023

Baba Raghav Das Medical College
2023

Regional Medical Research Center
2023

Sido Kanhu Murmu University
2022

Sambalpur University
2006-2022

Alpha-ketoglutarate (AKG) is a key metabolite of the tricarboxylic acid (TCA) cycle, an essential process influencing mitochondrial oxidative respiration rate.Recent studies have shown that dietary AKG reduces mTOR pathway activation by inhibiting ATP synthase, thereby extending lifespan nematodes.Although also extends in fruit flies, antiaging mechanisms these organisms remain unclear.In present study, we explored changes gene expression associated with extension Drosophila mediated...

10.18632/aging.102045 article EN cc-by Aging 2019-06-26

Abstract The hypothalamic-pituitary-ovarian (HPO) axis regulates the breeding process cycle of laying hens. However, key regulatory genes HPO and pathways that drive chicken egg performance remain elusive. A total 856 Chinese Luhua was raised highest two hundred lowest production were considered as high (HEP) low (LEP) according to number at 300 days age, respectively. RNA-seq sequencing (RNA-Seq) conducted explore transcriptome from hypothalamus, pituitary gland ovary tissue 6 with 3...

10.1038/s41598-020-62886-z article EN cc-by Scientific Reports 2020-04-06

Aflatoxin B1 (AFB1) leads to a major risk poultry and its residues in meat products can also pose serious threat human health. In this study, after feeding 165-day-old Roman laying hens for 35 days, the toxic effects of aflatoxin at different concentrations were evaluated. The purpose study was explore mechanism liver toxicosis responses AFB1. We found that highly group exposure resulted fat deposition, increased interstitial space, hepatocyte apoptosis hens. Furthermore, total 164...

10.3390/toxins12050290 article EN cc-by Toxins 2020-05-04

Abstract The gut microbiota helps the host to absorb nutrients and generate immune responses that can affect behavior, development, reproduction, overall health. However, in most of previous studies, was sampled mainly using feces intestinal contents from mammals but not wild reptiles. Here, we described bacterial profile five different gastrointestinal tract (GIT) segments (esophagus, stomach, small intestine, large cloaca) three Rhabdophis subminiatus 16S rRNA V4 hypervariable amplicon...

10.1002/mbo3.789 article EN cc-by MicrobiologyOpen 2019-03-07

The transcriptional profiles of mammals during brain development and ageing have been characterized. However the global expression patterns transcriptome in chicken not explored. Here, we systematically investigated temporal lncRNAs mRNAs across 8 stages (including 3 embryonic stages, 2 growth adult stages) female cerebrum. We identified 39,907 putative 14,558 mRNAs, by tracking a set age-dependent genes predicted potential biological functions based on co-expression network. results showed...

10.1186/s12864-018-5301-x article EN cc-by BMC Genomics 2018-12-01

Abstract Background The microbiota of the female reproductive tract is increasingly recognized as playing fundamental roles in animal reproduction. To explore relative contribution microbiomes to egg production chickens, we investigated multiple and digestive sites from 128 layer (egg-producing) chickens comparable environments. Results We identified substantial differences between diversity, composition, predicted function site-associated microbiota. Differences were more strongly...

10.1093/gigascience/giab067 article EN cc-by GigaScience 2021-09-01

Animal gut microbiota begins to colonize after birth and is functionally indispensable for maintaining the health of host. It has been reported that gender age influence composition intestinal microbiome. However, effects on microorganism forest musk deer (FMD) remain unclear. The aim this study was establish relationship between structure fecal male female with age. Here, Illumina Miseq 300PE sequencing platform targeting 16S rRNA V3–V4 hypervariable region applied define FMD two groups,...

10.1155/2019/9291216 article EN cc-by BioMed Research International 2019-11-18

1. Dulong Chickens (DLCs) live at high altitude (~3000 m) and humidity (~90%), are endemic to the Yunnan province, have gradually developed unique physiological characteristics, but their genetic basis is still unclear. Using fixation index (FST) approach, based on whole-genome resequencing, DLCs were analysed uncover genomic architecture of population candidate genes involved in selection during domestication.2. A total 469 obtained be putatively under DLCs. Further investigations revealed...

10.1080/00071668.2020.1792832 article EN British Poultry Science 2020-07-06

The frequency and severity of adverse reactions are the main reasons for low compliance mass drug administration (MDA) under Programme to Eliminate Lymphatic Filariasis (PELF). This paper reports types during two MDAs January 2002 September 2004 in State Orissa, India. Of people who consumed drugs, 15.5% MDA 16.5% reported one or more reactions. rate is higher (49.7%) a group individuals were monitored 6 days from day consumption drugs MDA. However, many these mild. No significant difference...

10.1016/j.trstmh.2005.07.016 article EN Transactions of the Royal Society of Tropical Medicine and Hygiene 2005-11-09

In a study undertaken among rural and urban communities in district of Orissa, India, the personal-protection measures used against mosquitoes, household costs these measures, were investigated. Most people living perceived mosquitoes as problem, both biting nuisance vectors human disease. Almost all (99%) households investigated most (84%) each reported use at least one measure mosquitoes. (92% 64% rural) 'modern' chemical method (coils, vaporizing mats, liquid vaporizers or sprays), with...

10.1179/136485907x193897 article EN Annals of Tropical Medicine and Parasitology 2007-10-01

MicroRNA (miRNA) is known to be an important regulator of muscle growth and development. The regulation microRNA on the skeletal phenotype animals mainly achieved by regulating proliferation differentiation myoblasts. In this study, we sequenced a total 60 samples from 15 developing stages pectoral five other tissues at 300 days Tibetan chicken. We characterized expression patterns miRNAs across developmental stages, found that chicken development stage was divided into early-embryonic...

10.3389/fgene.2020.00570 article EN cc-by Frontiers in Genetics 2020-06-23

In this study, a wide range of in silico investigation Bubalus bubalis (BB) heat shock protein 70 (HSP70) and factor-1 (HSF1) has been performed, ranging from sequence evaluation among species to homology modeling along with their docking studies decipher the interacting residues both molecules.Protein sequences BB HSP70 HSF1 were retrieved NCBI database FASTA format. Primary secondary structure prediction computed using Expasy ProtParam server Phyre2 server, respectively. TMHMM was used...

10.14202/vetworld.2019.2036-2045 article EN cc-by Veterinary World 2019-12-01

In this study, mitochondrial D-loop sequence data on riverine, swamp and hybrid buffaloes from India have been generated compared with other reported Indian Chinese Bangladeshi buffalo populations. Sequence analysis revealed the presence of 132 haplotypes, a haplotype diversity 0.9611 ± 0.0045 nucleotide 0.04801 0.00126. For first time, existence riverine-swamp hybrids among Chilika population has recorded, having 49 chromosomes, which was also confirmed by sharing between as well...

10.1111/age.12938 article EN Animal Genetics 2020-04-12

In India, the programme to eliminate lymphatic filariasis, which is largely based on mass administrations of diethylcarbamazine, has, in terms coverage and compliance, been generally much less successful urban areas than rural communities. An innovative strategy make more effective settings, an inclusive partnership community participation, has recently developed. evaluation strategy's implementation Orissa, employed both quantitative qualitative methods data collection, revealed...

10.1179/136485906x118521 article EN Annals of Tropical Medicine and Parasitology 2006-09-18

1. Lysozyme activity was estimated in plasma and leucocytes of twelve children suffering from kwashiorkor, thirteen with ocular signs vitamin A deficiency ten apparently normal acting as controls. 2. The results showed that the lysozyme significantly reduced kwashiorkor A-deficient children. Following therapy, levels enzyme were restored to normal. 3. initial both groups did not differ control value, changed after treatment. 4. It is suggested decreased one factors responsible for diminished...

10.1079/bjn19740084 article EN British Journal Of Nutrition 1974-09-01

In this study the nucleotide diversity in 5'untranslated region (UTR) of TLR8 gene riverine as well swamp buffaloes has been described. Analysis 5'UTR showed presence two SNPs region, g.-139G>T and g.-128A>G. A PCR-RFLP assay designed for genotyping SNP across 667 samples from 2 buffalo populations revealed a striking difference allele frequency distribution buffaloes. The T was higher compared to buffalo, ranging 0.71 1. G on other hand exhibited all Indian breeds/populations. principal...

10.1016/j.mgene.2013.08.001 article EN cc-by-nc-nd Meta Gene 2013-11-02

In utero exposure has been considered as a risk factor for filarial infection. To evaluate the influence of maternal infection on filarial-specific IgG subclass response in neonates and their correlation with plasma levels IL-10 interferon-γ, 145 pairs mothers respective cord bloods were examined. Transplacental transfer circulating antigen (CFA) was observed 34·8% from CFA positive mothers. Filarial-specific IgG1, IgG2 IgG4 responses found to be positively correlated contrast, IgG3...

10.1111/pim.12121 article EN Parasite Immunology 2014-06-05
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