A5101593355- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Atrial Fibrillation Management and Outcomes
- Heart Rate Variability and Autonomic Control
- Cardiovascular Syncope and Autonomic Disorders
- Cardiovascular Effects of Exercise
- Cardiovascular Function and Risk Factors
- Viral Infections and Immunology Research
- Cardiac pacing and defibrillation studies
- Cardiomyopathy and Myosin Studies
- Cardiovascular Disease and Adiposity
- interferon and immune responses
- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Extracellular vesicles in disease
- Cardiac Imaging and Diagnostics
- Polysaccharides and Plant Cell Walls
- Phytase and its Applications
- Animal Virus Infections Studies
- Blood Pressure and Hypertension Studies
- Atherosclerosis and Cardiovascular Diseases
- Respiratory and Cough-Related Research
- Cardiac Structural Anomalies and Repair
- Streptococcal Infections and Treatments
- Inflammatory Biomarkers in Disease Prognosis
Chinese Academy of Medical Sciences & Peking Union Medical College
2015-2025
East China Normal University
2024
Kunming Medical University
2024
First Hospital of China Medical University
2024
Second Affiliated Hospital of Zhejiang University
2024
Peking Union Medical College Hospital
2024
China Medical University
2024
Sichuan University
2024
Fu Wai Hospital
2016-2024
State Key Laboratory of Cardiovascular Disease
2016-2023
Abstract Background and Aims It remains unknown whether the brain glymphatic system, which is driven by heartbeat-driven pulsation of arteries responsible for cerebral waste clearance, impaired in atrial fibrillation (AF) mediates cognitive dysfunction related to AF. The aim this study was assess alterations AF, their role function, catheter ablation can improve activity. Methods In case-control prospective before–and–after study, patients with AF healthy controls (HCs) were enrolled....
Autoimmune myocarditis, with increasing incidence and limited therapeutic strategies, is in urgent need to explore its underlying mechanisms effective drugs. Pyroptosis a programmed cell death that may contribute the pathogenesis of myocarditis. Nonetheless, no direct evidence validated role pyroptosis autoimmune Lupeol (Lup), pentacyclic triterpene, possesses various biological activities such as antidiabetic properties. However, effects Lup on myocarditis remain unelucidated.
Abstract Aims Catheter ablation of ventricular tachycardia (VT) improves VT-free survival in ‘classic’ arrhythmogenic right cardiomyopathy (ARVC). This study aims to investigate electrophysiological features and outcomes patients with ARVC biventricular (BiV) involvement. Methods results We assembled a retrospective cohort definite cases sustained VTs. Patients were divided into the BiV (BiV involvement) group (RV) (isolated RV based on left systolic function detected by cardiac magnetic...
Background The association between DNA methylation age acceleration (DNAmAA) and cardiovascular‐kidney‐metabolic (CKM) syndrome stages long‐term mortality in the population with CKM remains unclear. Methods Results This cohort study included 1889 participants from National Health Nutrition Examination Survey (1999–2002) data. DNAmAA was calculated as residuals regression of on chronological age. primary outcome all‐cause mortality, cardiovascular noncardiovascular secondary outcomes....
Alcoholic cardiomyopathy (ACM) results from chronic alcohol misuse and primarily affects the working-age population (15-64 years). The global age-standardized rates (ASRs) of ACM disease burden declined slightly 1990 to 2021, but absolute cases increased, especially in high‒medium sociodemographic index (SDI) regions such as Eastern Europe. aim this study was inform strategies combat preventable yet escalating health issue. We calculated estimated annual percentage changes (EAPCs) quantify...
Abstract Aims The aim of this study was to investigate the outcomes catheter ablation (CA) in preventing arrhythmic events among patients with symptomatic Brugada syndrome (BrS) who declined implantable cardioverter defibrillator (ICD) implantation. Methods and results A total 40 BrS were included study, which 18 refused ICD implantation underwent CA, while 22 received employed substrate modification (including endocardial epicardial approaches) ventricular fibrillation (VF)-triggering...
Protein glutaminase can catalyze the hydrolysis of glutamine residues in plant proteins into glutamic acid to enhance functional properties. However, yield PG Chryseobacterium proteolyticum was too low be used industrial production. In this study, C. TM1040 increased by 121%, up 7.30 U/mL a 15L fermenter after medium optimization. Subsequently, purified obtained cation exchange chromatography (CEX) coupled with hydrophobic interaction (HIC). The degree deamidation (DD) wheat gluten 87.11%,...
Protein glutaminase (PG), originating from Chryseobacterium proteolyticum, can catalyze the deamidation of glutamine residues in plant proteins into glutamic acid, thus enhancing its functional properties. However, low yield PG limits industrial production. In this study, C. proteolyticum TM1040 increased by 121 %, up to 7.30 U/mL a 15 L fermenter after medium optimization. Subsequently, purified was obtained cation exchange chromatography (CEX) coupled with hydrophobic interaction (HIC)....
Cardioneuroablation (CNA) has shown encouraging results in patients with vasovagal syncope (VVS). However, data on different subtypes was scarce.
Abstract Aims Advanced atrial fibrillation (AF) is currently a dilemma for electrophysiologists when choosing minimally invasive treatment strategy. Previous studies have demonstrated the outcome of either catheter ablation or thoracoscopic surgical (SA) unsatisfactory in these patients. Whether hybrid (HA) could improve outcomes patients unknown. The purpose this study was to evaluate clinical efficacy HA advanced AF. Methods and results A randomized controlled trial designed enrol with...
Atrial fibrillation (AF) is associated with inflammation and endothelial dysfunction. However, the association between (as indexed by high-sensitivity C-reactive protein, hs-CRP) function [as big endothelin-1 (ET-1)] in AF patients remains unclear.We enrolled 128 lone AF, among which 83 had paroxysmal 45 persistent AF. Eighty-two age- gender-matched controls of supraventricular tachycardia without history were evaluated. Plasma hs-CRP, ET-1 levels other clinical characteristics compared...
Catheter ablation of premature ventricular contractions (PVCs) that trigger polymorphic tachycardia (PVT) or fibrillation has been reported as a novel therapy to reduce the syncope events in patients with catecholaminergic PVT, whereas long-term outcome and its value improving exercise-induced arrhythmias remain unclear.