A5102982788- Echinoderm biology and ecology
- Neurobiology and Insect Physiology Research
- Invertebrate Immune Response Mechanisms
- Cancer, Hypoxia, and Metabolism
- Plant and Biological Electrophysiology Studies
University of Cambridge
2024-2025
Institut Curie
2024
Inserm
2024
Université Paris Sciences et Lettres
2024
Centre National de la Recherche Scientifique
2024
Tissue maintenance is underpinned by resident stem cells whose activity modulated microenvironmental cues. Using Drosophila as a simple model to identify regulators of cell behaviour and survival in vivo , we have identified novel connections between the conserved transmembrane proteoglycan Syndecan, nuclear properties function. In midgut, Syndecan depletion intestinal results their loss from tissue, impairing tissue renewal. At cellular level, alters shape, causes lamina invaginations DNA...
Abstract Tissue maintenance is underpinned by resident stem cells whose activity modulated microenvironmental cues. Using Drosophila as a simple model to identify regulators of cell behaviour and survival in vivo , we have identified novel connections between the conserved transmembrane proteoglycan Syndecan, nuclear properties function. In midgut, Syndecan depletion intestinal results their loss from tissue, impairing tissue renewal. At cellular level, alters shape, causes lamina...
Abstract Organ development relies on complex molecular mechanisms that guide initially homogeneous populations of stem cells to differentiate into specialized cell types within defined spatial patterns. While stable during homeostasis, the proper organization must be re-established in case tissue injury for successful regeneration organ shape and function. How commit a differentiation path is central question research; however, coordination between geometry fate specification remains...