A5101957130- Nonmelanoma Skin Cancer Studies
- Polyomavirus and related diseases
- Cutaneous Melanoma Detection and Management
- Cutaneous lymphoproliferative disorders research
- Herpesvirus Infections and Treatments
- Public Health Policies and Education
- Educational Games and Gamification
- Zoonotic diseases and public health
- Autoimmune Bullous Skin Diseases
- Dermatological and Skeletal Disorders
- Eosinophilic Disorders and Syndromes
- Eating Disorders and Behaviors
- Viral Infections and Outbreaks Research
- Organ Donation and Transplantation
- Viral-associated cancers and disorders
- Nail Diseases and Treatments
- Bartonella species infections research
- CNS Lymphoma Diagnosis and Treatment
- COVID-19 Digital Contact Tracing
- Circadian rhythm and melatonin
- Celiac Disease Research and Management
- Syphilis Diagnosis and Treatment
- Nuclear Receptors and Signaling
- Antibiotic Use and Resistance
- Climate Change and Health Impacts
Samsung Medical Center
2024-2025
Sungkyunkwan University
2024-2025
University College London
2012-2024
University of Exeter
2024
MRC Clinical Trials Unit at UCL
2024
Lankenau Institute for Medical Research
2019-2022
Global VetPathology
2021
Emory University
2019
Oklahoma State Department of Health
2019
Centers for Disease Control and Prevention
2016-2019
Abstract Aging is a major risk factor for the majority of human diseases, and development interventions to reduce intrinsic rate aging expected age-related diseases including cardiovascular disease, cancer, dementia. In skin, manifests itself in photodamage dermal atrophy, with underlying tissue reduction impaired barrier function. To determine whether rapamycin, an FDA-approved drug targeting mechanistic target rapamycin (mTOR) complex, can senescence markers exploratory,...
The optimal timing of radiotherapy (RT) after radical prostatectomy for prostate cancer has been uncertain. RADICALS-RT compared efficacy and safety adjuvant RT versus an observation policy with salvage prostate-specific antigen (PSA) failure.
Case investigation and contact tracing are core public health tools used to interrupt transmission of pathogens, including SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19); timeliness is critical effectiveness (1,2). In May 2020, CDC funded* 64 state, local, territorial departments† support COVID-19 response activities. As part monitoring process, case metrics for June 25-July 24, were submitted by 62 departments. Descriptive analyses load, timeliness, yield (i.e.,...
Organ transplant recipients have a higher incidence of skin cancer. This risk is magnified over time and with continued exposure to immunosuppression. Skin cancer in nonwhite patients associated greater morbidity mortality owing diagnosis at more advanced stage, which suggests that organ are even risk.To describe demographic clinical factors the recipients.We performed retrospective medical record review who were (154 white 259 [black, Asian, Hispanic, Pacific Islander]) seen from November...
There is a paucity of evidence to guide physicians regarding prevention strategies for cutaneous squamous cell carcinoma (CSCC) in solid organ transplant recipients (SOTRs).To examine the development and results Delphi process initiated identify consensus-based medical management recommendations CSCC SOTRs.Dermatologists with more than 5 years' experience treating SOTRs were invited participate. A novel actinic damage skin cancer index (AD-SCI), consisting 6 ordinal stages corresponding an...
Squamous cell carcinoma (SCC) is the most common skin cancer diagnosed in solid organ transplant recipients (OTRs) and confers significant mortality. The development of SCC genital region elevated nonwhite OTRs. Viral induction, specifically human papillomavirus (HPV), hypothesized to play a role pathophysiology these lesions.To assess prevalence types lesions observed OTRs.This retrospective review included 496 OTRs who underwent full examination from November 1, 2011, April 28, 2017, at an...
The risk for skin cancer has been well characterized in white organ transplant recipients (OTRs); however, most patients on the waiting list United States are nonwhite. Little is known about cutaneous disease and this OTR population.To compare incidence of between nonwhite OTRs.This retrospective review medical records included 412 OTRs treated from November 1, 2011, through April 22, 2016, at an academic referral center. Prevalence characteristics were compared 154 258 (ie, Asian, Hispanic,...
Optimal fluid strategy for laparoscopic donor nephrectomy (LDN) remains unclear. LDN has been a domain liberal management to ensure graft perfusion, but this can result in adverse outcomes due overload. We compared postoperative outcome of living kidney donors according the intraoperative management. Five hundred and five LDNs performed over six-year period at tertiary hospital were analyzed. Donors divided into tertiles crystalloid infusion rate (ml/kg/hr), associations between tertile...
Organ transplant recipients (OTRs) are at increased risk of cutaneous malignancy. Skin disorders in OTRs color (OTRoC) have rarely been systematically assessed. We aimed to ascertain the burden skin disease encountered OTRoC by prospectively collecting data from attending 2 posttransplant surveillance clinics: 1 London, UK and Philadelphia, USA. Retrospective review all dermatological diagnoses was performed. Data 1766 were analyzed: 1024 (58%) white, 376 (21%) black, 261 (15%) Asian, 57...
Introduction: Poor diet, and the consumption of foods high in fat, sugar salt are common causes numerous health conditions premature mortality. Computerised food response inhibition training (food-RIT) is a type intervention found to aid weight loss reduce snacking these with motor responses proposed operate through process stimulus devaluation. However, interventions repetitive by nature suffer from lack adherence, leading some propose gamification as solution increase engagement. The...
Context: CDC's Epidemiology and Laboratory Capacity for Infectious Diseases (ELC) Cooperative Agreement aims to help health departments strengthen core epidemiology capacity needed respond a variety of emerging infectious diseases. In fiscal year 2014, $6 million was awarded 41 flexible epidemiologists (FEs). FEs were intended meet departments' unique needs support unanticipated events that could require the diversion resources specific or reemerging Objective: Explore multiple perspectives...
The 2014 Ebola outbreak revealed biosafety vulnerabilities across the United States. We distributed $24.1 million to health departments support public laboratories (PHLs) and sentinel clinical laboratory partners improve practices. used 9 indicators evaluate PHLs associated from March 2015 through April 2018 using descriptive statistics. On average, over 6 reporting periods, 59 awardee 4,040 responded. By 2018, 92% (57 of 62) had conducted at least 1 risk assessment for work with another...
Primary biliary cirrhosis (PBC) is an autoimmune disease of the liver characterized by presence highly specific antimitochondrial antibodies with resulting immune-mediated injury small intrahepatic bile ducts.1James W.D. Berger T. Elston D. Andrews' Diseases Skin: Clinical Dermatology. Saunders/Elsevier, London2011Google Scholar Palmoplantar keratodermas (PPKs) are hyperkeratosis skin on palms and soles.2Al-Harthy N. Kumagi Natural history management primary cirrhosis.Hepat Med. 2012; 4:...
Decompensated cirrhotic patients experience severely increased intestinal permeability and bacterial translocation. Thus, autologous blood salvaged during deceased donor liver transplantation (DDLT) may be contaminated with enteric bacteria. We aimed to evaluate contamination of DDLT its association post-transplant bacteremia. In 30 undergoing DDLT, culture was performed in samples: one before graft reperfusion (non-leukoreduced) two after (non-leukoreduced leukoreduced). The primary outcome...
Food response inhibition training (food-RIT) is found to aid weight loss and reduce snacking of foods high in sugar, salt fat. However, these interventions suffer from a lack adherence, with gamification proposed as solution increase engagement. The effect unclear, however, research investigating the effects single game elements improving adherence interventions. This study investigates whether isolated (social or feedback) improve engagement effectiveness food-RIT compared standard...