Prognostic indicators for gastrointestinal stromal tumors (GISTs) are under investigation. The latest risk classification criteria may still have room improvement. This study aims to investigate prognostic factors primary GISTs from three aspects, including clinicopathological parameters, immunohistochemical (IHC) expression of PTEN, and Ki-67 labeling index (LI), attempts find valuable predictors the malignancy potential GISTs. Tumor samples data 84 patients with after R0 resection were...

// Li Cao 1 , Chaowu Chen 2 Haihang Zhu Xuewen Gu Denghao Deng Xiuchun Tian Jun Liu Qin Xiao Department of Pathology, Clinical Medical College Yangzhou University, Subei People's Hospital Jiangsu Province, Yangzhou, 225001, P.R. China Gastroenterology, Correspondence to: Chen, email: doctorchencw@163.com Keywords: gastric cancer, MMP16, survival analysis, proliferation, invasion Received: March 30, 2016 Accepted: June 06, Published: 20, ABSTRACT Matrix metalloproteinases (MMPs) are closely...

AIM:To determine if serum inter-cellular adhesion molecule 1 (ICAM-1) is an early marker of the diagnosis and prediction severe acute pancreatitis (SAP) within 24 h onset pain, to compare sensitivity, specificity prognostic value this test with those physiology chronic health evaluation (APACHE) Ⅱ score interleukin-6 (IL-6). METHODS:Patients (AP) were divided into two groups according Ranson's criteria: mild (MAP) group SAP group.Serum ICAM-1, APACHE Ⅱand IL-6 levels detected in all...

To observe the therapeutic effect and mechanism of modified Banxia Houpu decoction on globus hystericus. The 95 patients with hystericus were randomly divided into a treatment group 46 cases treated control 49 Manyanshuning (Granula for Clearing Throat). In addition, normal 24 healthy people was set up. SCL-90 scale adopted to effect, evaluate psychological state build database combination four diagnoses. Houpo better than that in relieving depression, anxiety improving (P<0.05 or P<0.01)....

The effect of carbon dioxide (CO2) insufflation and warm-water infusion during colonoscopy on patients with chronic constipation remains unknown. We evaluated CO 2 irrigation versus air in unsedated China.This randomized, single-center, controlled trial enrolled 287 consecutive patients, from January 2014 to 2015, who underwent for constipation. Patients were randomized CO2 insufflation, insertion phase groups. Pain scores assessed by the visual analog scale (VAS). primary outcome was...

MicroRNAs (miRNAs) are important regulators of tumor formation, progression and metastasis. The present study characterized a novel miRNA (miR)‑888, as potent oncomiR in human colorectal cancer (CRC). clinicopathological investigation on 126 cases CRC patients demonstrated that the expression level miR‑888 was significantly upregulated tumors compared with adjacent healthy tissue, associated stage histological differentiation. A Kaplan‑Meier analysis log‑rank test increased exhibited...

Atrial fibrillation (AF) is the most prevalent form of arrhythmia, with a rising incidence and prevalence worldwide, posing significant implications for public health. In this paper, we introduce an approach that combines Recurrence Plot (RP) technique ResNet architecture to predict AF. Our method involves three main steps: filtering noise interference using wavelet decomposition, threshold denoising, reconstruction; generating RPs through phase space employing multi-level chained residual...

Abstract Mesoporous niobium‐based solid acid catalysts were successfully synthesized using the soft template method with sodium lignosulfonate (SLS) as template. In most studies is calcined to form mesopores after hydrothermal synthesis; however, in this study SLS was retained produce niobium‐carbon composite catalysts. The obtained characterized by X‐ray diffraction, nitrogen adsorption–desorption, Fourier transform infrared spectroscopy, scanning electron microscopy, thermogravimetric...

To the editor: The Non-steroidal antiinflammatory drugs (NSAIDs) are one of most widely prescribed drugs, commonly used for rheumatoid diseases and illnesses accompanied by pain. However, use NSAIDs is often limited gastrointestinal toxicity. inhibit cyclooxygenase (COX), which an enzyme in prostaglandin synthetic pathway, thereby decreasing pain, fever, inflammation. likely reason toxicity that gastric cytoprotection resulting from decreased.1 common adverse effects ibuprofen symptoms, such...

The aim was to explore the effect of negative pressure on proliferation and metastasis human pancreatic cancer SW1990 cells.Three groups were conducted in work: normal control group (NC group, 0 mm Hg), low (LN -300 high (HN -600 Hg).Cell morphological assay using an inverted Nikon TE2000-S microscope. Cell viability assayed cell counting kit-8 solution. apoptosis evaluated with flow cytometry. migration investigated transwell assay.Compared LN HN groups, cells NC grew quite well, showing a...

Gastrointestinal stromal tumors (GISTs) are mesenchymal that mainly arise in the gastrointestinal tract. They usually asymptomatic and incidentally discovered during endoscopy or surgery. Diagnosis is confirmed by histological examination of specimen. This case report an GIST small intestine diagnosed wireless capsule endoscopy. The tumor was initially suspected to be a leiomyoma, as GISTs young adults rare colorectal cancer screening. patient 35-year-old woman with occult bleeding, normal...

A 59-year-old man was hospitalized with acid reflux and diarrhea. Colonoscopy performed while the patient under propofol anesthesia, no abnormalities were observed. However, at 3.5 hours following colonoscopy, had persistent dull pain in lower abdomen.

Atrial fibrillation (AF) is the most prevalent form of arrhythmia, with a rising incidence and prevalence worldwide, posing significant implications for public health. In this paper, we introduce an approach that combines Recurrence Plot (RP) technique ResNet architecture to predict AF. Our method involves three main steps: using wavelet filtering remove noise interference; generating RPs through phase space reconstruction; employing multi-level chained residual network AF prediction. To...

Diabetic complications can affect multiple body systems,one of which is gastrointestinal tract.Diabetic diarrhea a common complication diabetic disorder.The prevalence caused by diabetes increasing rapidly and there are still many problems to be solved about its pathogenesis treatment.Recent studies show that the occurrence related emptying dysfunction gallbladder,exocrine pancreatic insufficiency,intestinal motility disorders,anorectal dysfunction,gastrointestinal hormone...

Prevalence of Helicobacter pylori in cirrhotic patients with portal hypertensive gastropathy

Objective To investigate the expression of doublecortin-like kinase 1 (DCLK1) in colorectal cancer and adenomas, it's role development progression carcinoma, explore relationship DCLK1 prognosis patients with diabetes medical history. Methods Expression 70 cases cancers, para-carcinoma tissues, 35 tubulovillous adenomas were detected by immunohistochemical method. Results ⑴ The high rate cancers was 41.4% (29/70), 45.7% (16/35) tubular villous both significantly higher than...

Objective To study the therapeutic effect of water method for patients with panhysterectomy in painless colonoscopy. Methods A total 300 undergoing colonoscopy were divided into two groups(the group, air group)randomly variation access time, withdrawal pain degrees and withdrawal, presence or absence assistance. Results There no significant differences intubation times (11.5±5.3 min VS 9.3±2.5 min) (5.5±0.9 6.2±1.3 (P>0.05). The degree was less group than that group(P<0.05)....