Zhichen Pu

ORCID: 0009-0003-1258-3506
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About
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Research Areas
  • Immune Response and Inflammation
  • RNA Interference and Gene Delivery
  • Cancer-related gene regulation
  • Inflammation biomarkers and pathways
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Inflammasome and immune disorders
  • Helicobacter pylori-related gastroenterology studies
  • Synthesis of Organic Compounds
  • Heme Oxygenase-1 and Carbon Monoxide
  • Cancer, Lipids, and Metabolism
  • Bioactive Compounds and Antitumor Agents
  • Peptidase Inhibition and Analysis
  • Immune Cell Function and Interaction
  • RNA modifications and cancer
  • High Altitude and Hypoxia
  • Cancer therapeutics and mechanisms
  • Mechanisms of cancer metastasis

Wannan Medical College
2024-2025

First Affiliated Hospital of Wannan Medical College
2013-2025

Zhengzhou University
2013

China Pharmaceutical University
2013

Capital Medical University
2013

Inner Mongolia Medical University
2013

Johns Hopkins University
1982

Purpose This study aimed to examine the impact of CA on DN and elucidate its underlying molecular mechanisms inflammation.

10.1080/10641963.2024.2326021 article EN cc-by-nc Clinical and Experimental Hypertension 2024-03-25

Inflammation induces tumor formation and plays a crucial role in progression prognosis. KCNK6, by regulating K(+) efflux to reduce NLRP3 Inflammasome-induced lung injury, relaxes the aorta. This study aims elucidate effects biological mechanism of KCNK6 inflammation-associated carcinogenesis, which may be essential for colon homeostasis defense system. To induce colitis, mice were given 3.0% Dextran Sodium Sulfate (DSS) their drinking water 7 days. The Azoxymethane (AOM) +DSS method was used...

10.1080/08830185.2024.2401358 article EN International Reviews of Immunology 2024-09-13

Abstract Diabetic foot ulcer (DFU) represents a severe complication of diabetes, mainly caused by peripheral vascular occlusion and infection, presenting significant clinical challenges in treatment potentially resulting gangrene, amputation, or even fatality. This study aimed to investigate the involvement underlying mechanisms Meteorin-like (Metrnl) pathogenic process DFU. Mice underwent diabetes induction streptozotocin, while human umbilical vein endothelial cells (HUVECs) were exposed...

10.1055/a-2502-8712 article EN Experimental and Clinical Endocrinology & Diabetes 2025-03-01
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