A5014646573- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Natural product bioactivities and synthesis
- Topological Materials and Phenomena
- Phytochemistry and Biological Activities
- 2D Materials and Applications
- Graphene research and applications
- Luminescence Properties of Advanced Materials
- Bioactive Natural Diterpenoids Research
- Perovskite Materials and Applications
- Advanced Condensed Matter Physics
- Phytochemical Studies and Bioactivities
- Cancer-related molecular mechanisms research
- Quantum Dots Synthesis And Properties
- Radiation Detection and Scintillator Technologies
- Sesquiterpenes and Asteraceae Studies
- Cardiovascular Function and Risk Factors
- Hepatocellular Carcinoma Treatment and Prognosis
- Metal complexes synthesis and properties
- Liver Disease Diagnosis and Treatment
- Quantum and electron transport phenomena
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Botanical Studies and Applications
- Traditional and Medicinal Uses of Annonaceae
Wuhan Institute of Technology
2023-2025
Guilin Medical University
2024-2025
Northeast Agricultural University
2020-2024
Shenyang Pharmaceutical University
2014-2024
The First People's Hospital of Shunde
2007-2024
Southern Medical University
2018-2024
Capital Medical University
2017-2024
Beijing Tian Tan Hospital
2024
Huazhong University of Science and Technology
2017-2023
Hunan University
2009-2023
SHARPIN is a tumor-associated gene involved in the growth and proliferation of many tumor types. A function cholangiocarcinoma (CCA) so far unclear. Here, we studied role CCA revealed its relevant molecular mechanism. The expression was analyzed tissues from patients using immunohistochemistry, quantitative PCR, western blot analysis. Expression suppressed/overexpressed by siRNA silencing or lentiviral overexpression vector, effect on cell determined CCK-8 assay flow cytometry. Accumulation...
Nearly one-quarter of all avian species is either threatened or nearly threatened. Of these, 73 are currently being rescued from going extinct in wildlife sanctuaries. One the previously most critically-endangered crested ibis, Nipponia nippon. Once widespread across North-East Asia, by 1981 only seven individuals two breeding pairs remained wild. The recovering ibis populations thus provide an excellent example for conservation genomics since every individual bird has been recruited genomic...
Abstract In spinful electronic systems, time-reversal symmetry makes that all Kramers pairs at the time-reversal-invariant momenta are Weyl points (WPs) in chiral crystals. Here, we find such symmetry-enforced WPs can also emerge bosonic systems (e.g. phonons and photons) due to nonsymmorphic symmetries. We demonstrate for some space groups, several high-symmetry k -points host only phononic dubbed (SEWPs). The SEWPs, enumerated Table 1, pinned boundary of three-dimensional (3D) Brillouin...
Triglyceride glucose (TyG) index is considered a new surrogate marker of insulin resistance that associated with the development vascular disease. The aim this study was to evaluate prognostic value TyG in patients acute myocardial infarction (AMI).A total 3181 AMI were included analysis. Patients stratified into 2 groups according their levels: <8.88 group and ≥8.88 group. incidence major adverse cardiovascular events (MACEs) during median 33.3-month follow-up recorded. Multivariable Cox...
Abstract Background Triglyceride glucose (TyG) index is considered a reliable alternative marker of insulin resistance and an independent predictor cardiovascular (CV) outcomes. However, the prognostic value TyG in patients with type 2 diabetes mellitus (T DM) acute myocardial infarction (AMI) remains unclear. Methods A total 1932 consecutive T DM AMI were enrolled this study. Patients divided into tertiles according to their levels. The incidence major adverse cardiac cerebral events...
By using ab initio calculations and symmetry analysis, we define a class of Weyl phonons: charge-four phonons (CFWPs) characterized by Chern number $\ifmmode\pm\else\textpm\fi{}4$ in their acoustic phonon spectra due to chiral point-group symmetries. Some high-symmetry points the space groups (SGs) phononic systems behaving as quadratic tend form CFWPs. As enumerated this paper, CFWPs are located at boundaries or center three-dimensional Brillouin zone protected time-reversal $\mathcal{T}$...
Two-dimensional (2D) semiconductors (SCs) integrated with two or more functions are the cornerstone for constructing multifunctional nanodevices but remain largely limited. Here, by tuning spin state of organic linkers and symmetry/topology crystal lattices, we predict a class unprecedented SCs in 2D Cr(II) five-membered heterocyclic metal frameworks that simultaneously possess auxetic effect, room-temperature ferrimagnetism, chiral ferroelectricity (FE), electrically reversible...
Abstract Semiconductor heterojunctions have garnered extensive interest in photocatalytic hydrogen generation, yet the limited light absorption and charge transfer efficiencies still restrict performance. The topological insulator has unique surface states high‐mobility electrons, demonstrating significant potential for enhancing photocatalysis. Herein, a ternary photocatalyst based on insulator, which CdS ZnS nanoparticles are grown Bi 2 Se 3 nanotube, is prepared efficient photocatalysis...
Two-dimensional (2D) room-temperature chiral multiferroic and magnetic topological materials are essential for constructing functional spintronic devices, yet their number is extremely limited. Here, by using the polar HPP (HPP = 4-(3-hydroxypyridin-4-yl)pyridin-3-ol) as an organic linker transition metals (TM Cr, Mo, W) nodes, we predict a class of 2D TM(HPP)2 organometallic nanosheets that incorporate homochirality, magnetism, ferroelectricity, nodes. The homochirality introduced linkers,...
Abstract Defects at the interface between perovskite and carrier transport layer are ≈100 times more prevalent than those within bulk, potentially serving as non‐radiative recombination centers to adversely affect extraction transport. Here, a green pyridoxine hydrochloride (PDHC) is introduced into SnO 2 quantum dots (QDs) solution. The resulting surface chloritization of QDs not only passivates defects, thereby strengthening contact among QDs, but also chemically interconnects with...
The aim of the present study is to construct a competitive endogenous RNA (ceRNA) regulatory network by using differentially expressed long noncoding RNAs (lncRNAs), microRNAs (miRNAs), and mRNAs in patients with hepatocellular carcinoma (HCC), prognostic model for predicting overall survival (OS) HCC patients. Differentially lncRNAs, miRNAs, were explored between tissues normal liver tissues. A was built OS receiver operating characteristic curves used evaluate performance model. There 455...
By using symmetry analysis and first-principles calculations, we propose that the simple cubic structure of copper chloride (CuCl) in high-pressure phase can be worked as a three-dimensional (3D) topological phononic material, hosting so-called nodal links (TPNLs) phonon spectra, which are intersected around center Brillouin zone (BZ). More interestingly, another class nodal-line phonons, i.e., hexahedron net (TPNHN), exists at all boundaries 3D BZ is composed interconnected quadruply...
By using first-principles calculations and symmetry analysis, we uncover that the rubidium-catena-telluridoaurate-family materials in space group (SG) 51 can exhibit ideal nodal-surface phonons separately three-dimensional Brillouin zone, characterized by nearly flat phonon bands their spectra. The nodal surfaces are protected both screw rotation time reversal symmetry. Moreover, our theoretical demonstrate composed twofold degenerate points, which form a straight singularity line (001)...
Aim: To evaluate the prognostic value of triglyceride-glucose (TyG) index in nondiabetic patients with acute coronary syndrome (ACS) low-density lipoprotein cholesterol (LDL-C) below 1.8 mmol/L.
Background: In order to further investigate the relationship of psychological well-being with depression and anxiety. Method: Students from five universities were solicited participate in this study 545 students a mean age 20.1 (SD = 2.2) years finally accessed analysis. Result: All six dimensions—autonomy (AU), environment mastery (EM), personal growth (PG), positive relationships others (PR), purpose life (PL), self-acceptance (SA)—of Scales Psychological Well-being Inventory (SPWB)...
Enzymes involved in collagen biosynthesis, including lysyl oxidase (LOX), have been proposed as potential therapeutic targets for idiopathic pulmonary fibrosis. LOX expression is significantly upregulated bleomycin (BLM)-induced lung fibrosis, and knockdown of or inhibition activity alleviates the Unexpectedly, treatment mice with inhibitor at inflammatory stage, but not fibrogenic efficiently reduces deposition normalizes architecture. Inhibition impairs cell infiltration, TGF-β signaling,...
Prunus tomentosa seeds were researched for antioxidant and anti-inflammatory constituents. By activity-guided fractionation of P. seed extract, six new dihydrobenzofuran neolignans, prunustosanans AI-IV (1–4) prunustosanansides AI AII (5 6), together with 10 known compounds (7–16) isolated from bioactive fraction. The structures determined by spectroscopic analyses, especially NMR, HRESIMS, CD spectra. activity was greatest 5, 10, 12 against DPPH radical 8, 9, 13 ABTS radical. Moreover, 7 11...
During the process of manufacturing hawthorn (Crataegus pinnatifida) juice and jam, a significant quantity byproducts (leaves, seeds) is generated. The antioxidant anti-inflammatory bioassay-guided fractionation extract seeds has led to isolation eight new lignans, hawthornnins A-H (1-8), seven known analogues (9-15). Their structures were elucidated by spectroscopic techniques, including 1D 2D NMR CD spectra. radical-scavenging effects all isolated compounds investigated. 1-6 8 showed...
Type IV collagens (Col IV), components of basement membrane, are essential in the maintenance tissue integrity and proper function. Alteration Col is related to developmental defects diseases, including cancer. α chains form α1α1α2, α3α4α5 α5α5α6 protomers that further collagen networks. Despite knowledge on functions major (α1α1α2), little known whether minor (α3α4α5 α5α5α6) plays a role It also remains be elucidated functionally redundant. We show α5 chain indispensable cancer development...