A5100382012- Cervical and Thoracic Myelopathy
- Advanced Neural Network Applications
- Spine and Intervertebral Disc Pathology
- Psychological and Temporal Perspectives Research
- AI in Service Interactions
- RNA modifications and cancer
- Mind wandering and attention
- Respiratory viral infections research
- Advanced Image and Video Retrieval Techniques
- Bone health and osteoporosis research
- Pneumonia and Respiratory Infections
- Cognitive Functions and Memory
- Antibiotic Use and Resistance
- Viral-associated cancers and disorders
- Immune Cell Function and Interaction
- Robotics and Sensor-Based Localization
- Plant Stress Responses and Tolerance
- Pneumocystis jirovecii pneumonia detection and treatment
- Surgical Sutures and Adhesives
- Antibiotics Pharmacokinetics and Efficacy
- Stroke Rehabilitation and Recovery
- Antibiotic Resistance in Bacteria
- Antifungal resistance and susceptibility
- Hepatitis B Virus Studies
- Diabetes Treatment and Management
University of Illinois Chicago
2017-2025
Second Hospital of Anhui Medical University
2022-2025
Anhui Medical University
2021-2025
Lanzhou University
2023-2025
Wenzhou Medical University
2022-2024
Peking University
2023-2024
Shanghai Academy of Agricultural Sciences
2022-2024
Peking University Shenzhen Hospital
2024
Lishui Central Hospital
2024
Chongqing Medical University
2022-2024
Visceral obesity is associated with high cardiovascular events risk in type 2 diabetes mellitus (T2DM). Whether normal-weight visceral will pose a higher atherosclerotic disease (ASCVD) than body mass index (BMI)-defined overweight or obese counterparts without remains unclear. We aimed to explore the relationship between general and 10-year ASCVD patients T2DM.Patients T2DM (6997) who satisfied requirements for inclusion were enrolled. Patients considered have normal weight when 18.5 kg/m2...
Background There is a dearth of feasibility assessments regarding using large language models (LLMs) for responding to inquiries from autistic patients within Chinese-language context. Despite Chinese being one the most widely spoken languages globally, predominant research focus on applying these in medical field has been English-speaking populations. Objective This study aims assess effectiveness LLM chatbots, specifically ChatGPT-4 (OpenAI) and ERNIE Bot (version 2.2.3; Baidu, Inc),...
Given a graph $G$, denote by $h(G)$ the smallest size of subset $V(G)$ which intersects every maximum independent set $G$. We prove that any $G$ without induced matching $t$ satisfies $h(G)\le \omega(G)^{3t-3+o(1)}$. This resolves conjecture Hajebi, Li and Spirkl [Hitting all stable sets in $P_{5}$-free graphs. J. Combin. Theory Ser. B, 165:142-163, 2024].
Abstract The safety and immunogenicity of a protein-based tetravalent vaccine SCTV01E that contains spike protein ectodomain (S-ECD) Alpha, Beta, Delta Omicron BA.1 are assessed compared with bivalent SCTV01C (Alpha Beta variants) monovalent mRNA (NCT05323461). primary endpoints the geometric mean titers (GMT) live virus neutralizing antibodies (nAb) to (B.1.617.2) at day 28 post-injection. secondary include safety, 180 GMTs against BA.1, BA.5, seroresponse rates T cell responses 450...
ProOmpA is a preprotein that translocated across the plasma membrane by general secretory pathway in Escherichia coli.The molecular chaperon SecB Sec can recognize and bind proOmpA for its translocation.However, structure of SecB/proOmpA complex remains unknown.Here, we constructed an uncleavable fused with metallothionein at C-terminus labeled it metals vitro study cryo-electron microscopy.Using single particle microscopy, reconstructed 3D stable complex.The shows major portion locates on...
ABSTRACT Backgrounds and Aims CD8+T cells are crucially associated with the fight against hepatitis B virus (HBV) infection. CD161 has been shown to express remarkably on HCV‐specific cells. However, accurate function of CD161+CD8+T in HBV immunity or pathogenesis remains undetermined. Methods Blood samples were collected from 25 chronic (CHB) patients. Peripheral blood levels their correlation serum ALT analyzed CHB To analyze vivo cell's number, function, intrahepatic recruitment...
The GRAS gene family encodes a group of plant-specific transcription factors essential for regulating plant growth, development and stress responses. While the has been extensively studied in various species, comprehensive characterization Medicago ruthenica not yet conducted. In this study, total 62 MrGRAS members were identified through whole-genome analysis M. ruthenica, phylogenetic categorized these genes into 13 distinct groups. Gene structure conserved domain showed that from same...
Carbapenem-resistant Klebsiella pneumoniae (CRKp) poses a major threat to global public health. This study aimed investigate the genomic characteristics and phylogenetic relatedness of colonization infection with CRKp among intensive care unit (ICU) patients. A total 61 isolates, including 29 non-ICU-acquired 32 ICU-acquired strains, were collected by active screening culture from 16 ICUs through multicenter cohort study. Following whole-genome sequencing (WGS), seven sequence types (STs)...
Improper medical waste management threatens public health and the environment. The objective of this study was to investigate practices in different level hospitals. A multicenter conducted 566 hospitals Anhui Province, China. self-designed online questionnaire applied collect hospital's characteristics, amount handling waste, occupational safety measures. average generation rates were 0.62 kg/bed, 0.43 0.46 kg/bed per day tertiary hospitals, secondary primary respectively. Different levels...
The isolation and culture of Mycoplasma pneumoniae (MP) is time-consuming has a low success rate. On the basis fact that cell lines are susceptible to MP contamination, we explored possibility using Hep-2 for MP, overcome this long-standing technical problem. Quantitative Real-time PCR (qPCR) was used detect in nucleic acid samples clinically suspected mycoplasma-infected patients. Positive were cultured cells, with classical commercial liquid medium serving as control. For successful broth...
SARS-CoV-2 led to the swift development of vaccines, and neutralization assays played a crucial role in assessing their effectiveness. A post-hoc analysis Phase I/II trial evaluated immunogenicity bivalent protein vaccine. We assessed vaccine using live virus (LVNA) pseudotyped (PVNA) measure antibody responses against different variants, including Alpha, Beta, Delta. Various statistical techniques, correlation coefficients, regression models, Bland–Altman plots, were employed assess...
ABSTRACT Axon guidance proteins have been found to play a regenerative role in the peripheral nervous system and cornea. Netrin‐4 is member of Netrins family axon implicated diabetic retinopathy corneal hemangiogenesis. However, its effects on nerve epithelium repair are not well understood. We performed vitro vivo studies assess wound healing. that induced extensive neurite growth branching trigeminal ganglia neurons accelerated scratch closure epithelial cells. In vivo, dual action...
Evolution of SARS-CoV-2 variants emphasizes the need for multivalent vaccines capable simultaneously targeting multiple strains. SCTV01E is a tetravalent COVID-19 vaccine derived from spike protein Alpha, Beta, Delta, and Omicron BA.1. In this double-blinded placebo-controlled pivotal efficacy trial (NCT05308576), primary endpoint was (VE) against seven days post-vaccination in individuals without recent infection. Other endpoints included evaluating safety, immunogenicity, VE all infections...
Candida bloodstream infection (BSI), the fourth most common nosocomial BSI, is an urgent global health challenge with tremendous growth in antifungal resistance rate and mortality rate.To establish epidemiology, species distribution, risk factors, 30-day of candidaemia among 115 patients this 6-year surveillance study.We retrospectively analyzed clinical characteristics, susceptibility patterns, factors for morbidity cases diagnosed one tertiary care hospital from January 2016 through...
The goal was to study the difference of virological, immunologic, and inflammatory indicators between Epstein-Barr associated infectious mononucleosis (EBV-IM) EBV hemophagocytic lymphohistiocytosis (EBV-HLH) explore evaluation for monitoring therapeutic efficacy EBV-HLH.
The number of pediatric respiratory tract infection cases in China has significantly increased this year, and
BACKGROUND: The effect of anti-osteoporosis treatment in elderly patients with osteoporosis and lumbar discectomy fusion (LIF) for degenerative diseases is not well known. OBJECTIVE: This study aimed to evaluate the perioperative LIF. METHODS: From January December 2022, were divided into three groups according inclusive criteria: normal group (Group A), osteopenia B) C). Quantitative computed tomography (QCT), height intervertebral space (HIS), segmental sagittal angle (SSA), visual...