A5102725698- Cancer, Lipids, and Metabolism
- Renal Diseases and Glomerulopathies
- CAR-T cell therapy research
- TGF-β signaling in diseases
- Epigenetics and DNA Methylation
- Child Development and Digital Technology
- Immunotherapy and Immune Responses
- Immune Cell Function and Interaction
- Chronic Lymphocytic Leukemia Research
- Smart Grid Security and Resilience
- Immune cells in cancer
- Virus-based gene therapy research
- Cryptographic Implementations and Security
- Advanced Malware Detection Techniques
- Lipoproteins and Cardiovascular Health
- Digital and Cyber Forensics
- Advanced biosensing and bioanalysis techniques
- Tuberous Sclerosis Complex Research
- Endoplasmic Reticulum Stress and Disease
- Cytomegalovirus and herpesvirus research
- Network Security and Intrusion Detection
- Hepatocellular Carcinoma Treatment and Prognosis
- Genetics and Neurodevelopmental Disorders
- Renal and related cancers
- Lung Cancer Research Studies
Capital Medical University
2023
Shantou University
2023
Southern Medical University
2009-2023
Foshan Maternity and Child Health Care Hospital
2023
Shantou University Medical College
2023
Beijing Tian Tan Hospital
2023
Huazhong University of Science and Technology
2023
Nanjing General Hospital of Nanjing Military Command
2022
Xinqiao Hospital
2022
Shandong University
2022
Glioblastoma (GBM) is a highly aggressive primary brain tumor with poor prognosis. This study investigates the therapeutic potential of human Vγ9Vδ2 T cells in GBM treatment. The sensitivity different glioma specimens to cell-mediated cytotoxicity assessed using patient-derived cell clusters (PTCs) model.The evaluates anti-tumor effect 26 cases through PTCs model. Protein expression BTN2A1 and BTN3A1, along gene related lipid metabolism inflammatory response pathways, analyzed matched tissue...
Acute myeloid leukemia (AML) is one of the most common hematopoietic malignancies in adults. The tumor microenvironment (TME) has a critical effect on AML occurrence, recurrence, and progression. gene feline virus subgroup C cellular receptor family member 2 (FLVCR2) belongs to major facilitator superfamily transporter protein members, which primarily involved transporting small molecules. potential role FLVCR2 TME not been investigated. To clarify expression AML, we analyzed Gene Expression...
Histone deacetylases (HDACs) inhibitors are promising therapeutic agents against proteinuric kidney diseases, here, we investigated the effect of MC1568, a selective inhibitor HDAC class IIa, on development and progression nephrotic syndrome in murine model induced by Adriamycin (ADR). In tissues FSGS patients, all four members IIa were significantly upregulated podocytes. ADR-treated cultured human podocyte, expression induced, meanwhile inhibition with MC1568 restored cytoskeleton...
Background and aims: Radiofrequency ablation (RFA) often suffered from incomplete for medium-to-large or irregular tumors. To solve this clinical problem, we proposed a new treatment strategy of OK-432 in combination anti- programmed cell death protein 1 (αPD-1) antibody residual tumors after RFA (iRFA) hepatocellular carcinoma (HCC).Approach results: The effect on immature dendritic cells (iDCs) was evaluated vitro. CCK-8 kit ELISPOT were used to assess the killing OK-432-induced CD8+ T...
Recently, backdoor attack has become an increasing security threat to deep neural networks and drawn the attention of researchers. Backdoor attacks exploit vulnerabilities in third-party pretrained models during training phase, enabling them behave normally for clean samples mispredict with specific triggers. Existing mainly focus on balanced datasets. However, real-world datasets often follow long-tailed distributions. In this paper, first time, we explore such Specifically, analyze...
Abstract Background Sex hormones, especially estrogen, which binds to estrogen receptor β (ERβ), play a vital role in the pathogenesis of mental disorders such as autism spectrum disorder (ASD). The purpose this study was analyze serum levels hormone receptors, including ERβ, progesterone (PGR) and androgen (AR), compare these between children with ASD typically developing (TD) children. We also investigated relationships ERβ mRNA core symptoms, sleep, developmental quotients (DQs) from...
Objective: To investigate risk factors for the long-term prognosis of primary focal segmental glomerulosclerosis (FSGS) and associated with renal in children. Methods: A retrospective study was conducted by collecting clinical data including general information, features pathological findings 124 children FSGS Department Pediatrics Jinling Hospital from January 2003 to December 2019. The cumulative survival rate calculated Kaplan-Meier analysis. related were identified Cox regression model...