- Heart Failure Treatment and Management
- Cardiovascular Function and Risk Factors
- Cardiac pacing and defibrillation studies
- Cardiac Structural Anomalies and Repair
- Mechanical Circulatory Support Devices
- Cardiac Arrhythmias and Treatments
- Cardiac Arrest and Resuscitation
- Cardiac Imaging and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Diabetes Treatment and Management
- Transplantation: Methods and Outcomes
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Cardiac Valve Diseases and Treatments
- Phonocardiography and Auscultation Techniques
- Diabetes Management and Research
- Cardiomyopathy and Myosin Studies
- Music and Audio Processing
- Synthesis of Organic Compounds
- 3D Printing in Biomedical Research
- Innovative Microfluidic and Catalytic Techniques Innovation
- Synthesis and biological activity
- Blood Pressure and Hypertension Studies
- Potassium and Related Disorders
- Traditional Chinese Medicine Studies
- Ultrasound in Clinical Applications
Yonsei University
2022-2025
Korea University
2025
Asan Medical Center
2014-2024
Myongji Hospital
2024
University of Ulsan
2014-2024
Ulsan College
2014-2024
Amazon (Germany)
2024
Ulsan University Hospital
2014-2024
Kwangju Christian Hospital
2024
Kyung Hee University
2022
Background: The morbidity and mortality of patients with functional mitral regurgitation (MR) remain high, but no pharmacological therapy has been proven effective. hypothesis this study was that sacubitril/valsartan would be superior to valsartan alone in improving MR via dual inhibition the renin-angiotensin system neprilysin. Methods: In double-blind trial, we randomly assigned 118 heart failure chronic secondary left ventricular (LV) dysfunction receive either or valsartan, addition...
Background and Objectives:The burden of heart failure has increased in Korea.This registry aims to evaluate demographics, clinical characteristics, management, long-term outcomes patients hospitalized for acute (AHF).Subjects Methods: We prospectively enrolled a total 5625 consecutive subjects AHF one 10 tertiary university hospitals from March 2011 February 2014.Descriptive statistics were used determine the baseline characteristics study population compare them with those other...
Objective There are conflicting results among previous studies regarding the prognosis of heart failure with preserved ejection fraction (HFpEF) compared reduced (HFrEF). This study aimed to compare outcomes patients de novo acute (AHF) or decompensated HF (ADHF) according HFpEF (EF≥50%), HFrEF (EF<40%) and define mid-range EF (HFmrEF, 40≤EF<50%). Methods Between March 2011 February 2014, 5625 consecutive AHF were recruited from 10 university hospitals. A total 5414 (96.2%) data...
The clinical characteristics and outcomes of acute heart failure (AHF) according to left ventricular ejection fraction (LVEF) have not been fully elucidated, especially for patients with mid-range LVEF. We performed a comprehensive comparison the epidemiology, patterns in-hospital management, in AHF different LVEF categories.
Worsening renal function (WRF) is associated with adverse outcomes in patients heart failure. We investigated the predictors and prognostic value of WRF during admission, preserved ejection fraction (HFpEF) versus those reduced (HFrEF).A total 5625 were enrolled KorAHF (Korean Acute Heart Failure) registry. was defined as an absolute increase creatinine ≥0.3 mg/dL. Transient recovery at discharge, whereas persistent indicated by a nonrecovered level. HFpEF HFrEF left ventricle ≥50% ≤40%,...
High glycemic variability (GV) is a poor prognostic marker in cardiovascular diseases. We aimed to investigate the association of GV with all-cause mortality patients acute heart failure (HF).The Korean Acute Heart Failure registry enrolled hospitalized for HF from 2011 2014. Blood glucose levels were measured at time admission, during hospitalization, and discharge. included those who had 3 or more blood measurements this study. Patients divided into two groups based on coefficient...
Introduction There have been few studies on predictors of weaning failure from MV in patients with heart (HF). We sought to investigate the predictive value B-lines measured by lung ultrasound (LUS) risk mechanical ventilation (MV) and in-hospital outcomes. Methods This was a single-center, prospective observational study that included HF who were invasive MV. LUS performed immediate before ventilator weaning. A positive exam defined as observation two or more regions had three count located...
Abstract Data are limited on the mechanisms underlying memory impairment in heart failure (HF). We hypothesized that angiotensin II (Ang II) may determine fate of adult hippocampal neural stem cells (HCNs), a cause HF. HCNs with neurogenesis potential were isolated and cultured from rat hippocampi. Ang decreased HCN proliferation dose- time-dependent manners. Moreover, treatment (1 µM) for 48 hours induced apoptotic death, which was attenuated by pretreatment receptor blockers (ARBs)....
Despite considerable advancements in deep learning, optimizing respiratory sound classification (RSC) models remains challenging. This is partly due to the bias from inconsistent recording processes and imbalanced representation of demographics, which leads poor performance when a model trained with dataset applied real-world use cases. RSC datasets usually include various metadata attributes describing certain aspects data, such as environmental demographic factors. To address issues caused...
<title>Abstract</title> Purpose Gaucher disease (GD) is an autosomal recessive condition caused by insufficient glucocerebrosidase activity. The Earlier Diagnosis Consensus (GED-C) initiative created a point-scoring system (PSS) to facilitate the early identification of GD based on significant indicators and covariables. This study aimed evaluate applicability utility GED-C PSS in pediatric young adult patients Korea. Results included both retrospective analysis prospective recruitment....
The predictive role of the vasoactive-inotropic score (VIS) for clinical outcomes after venoarterial extracorporeal membrane oxygenation (VA-ECMO) in patients with cardiogenic shock is not well known. This study investigated value VIS on in-hospital and determination optimal timing initiation VA-ECMO.
Mixed cardiogenic-septic shock (MS), defined as the combination of cardiogenic (CS) and septic (SS) shock, is often encountered in cardiac intensive care units. Herein, authors compared impact venoarterial extracorporeal membrane oxygenation (VA-ECMO) MS, CS, SS. Of 1,023 patients who received VA-ECMO from January 2012 to February 2020 at a single center, 211 with pulmonary embolism, hypovolemic aortic dissection, unknown causes were excluded. The remaining 812 grouped based on cause...
The aim of this study was to describe in more detail the predisposition, natural course, and clinical impact post-transplantation diabetes mellitus (PTDM) after heart transplantation (HT). characteristics outcomes 54 patients with PTDM were compared those 140 without PTDM. mean age significantly higher than controls (48.9 ± 9.3 vs 38.6 13.3 yr, respectively, P = 0.001), ischemic disease a common indication HT (20.4% [11/54] 7.1% [10/140], 0.008). In multivariate analysis, only recipient...
<h3>Objectives</h3> The purpose of this study is to examine the risk stroke in patients with heart failure normal ejection fraction (HFNEF) and atrial fibrillation (AF). <h3>Design</h3> Clinical echocardiographic data non-valvular AF who were not on anticoagulation retrospectively investigated. A total 304 had without failure, 102 diagnosed as HFNEF. <h3>Main outcome measures</h3> We compared rate ischaemic stroke, death composite these two groups. <h3>Results</h3> Patients HFNEF older than...