A5109926169- Viral Infections and Vectors
- Cancer Immunotherapy and Biomarkers
- Vector-Borne Animal Diseases
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Endometrial and Cervical Cancer Treatments
- Lung Cancer Treatments and Mutations
- Vector-borne infectious diseases
- Economic and Financial Impacts of Cancer
- interferon and immune responses
- Animal Virus Infections Studies
- Molecular Biology Techniques and Applications
- Plant Virus Research Studies
Jiangxi Maternal and Child Health Hospital
2024-2025
Suzhou Institute of Systems Medicine
2020-2022
Chinese Academy of Medical Sciences & Peking Union Medical College
2020
National Taiwan University
2007
Genomics Research Center, Academia Sinica
2007
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a widespread outbreak of highly pathogenic disease 2019 (COVID-19). It is therefore important and timely to characterize interactions between the virus host cell at molecular level understand its pathogenesis. To gain insights, we performed high-throughput sequencing that generated time-series data simultaneously for bioinformatics analysis genomes transcriptomes implicated in SARS-CoV-2 infection. Our results showed...
QL1604 is a highly selective, humanized monoclonal antibody against programmed death protein 1. We assessed the efficacy and safety of plus chemotherapy as first-line treatment in patients with advanced cervical cancer.
5509 Background: The phase 3 COMPASSION-16 trial demonstrated statistically significant progression-free survival (PFS) and overall (OS) benefits with cadonilimab plus chemotherapy ± bevacizumab in patients persistent, recurrent, or metastatic cervical cancer (R/M CC). This analysis assessed efficacy several key clinical subgroups. Methods: R/M CC pts who had no prior systemic treatment were randomized 1:1 to receive (10 mg/kg) placebo Q3W platinum-based (15 mg/kg). dual primary endpoints...
Abstract The genus Culicoides includes biting midges, some of which are vectors for viruses that cause diseases in humans and animals. Knowledge the roles viral ecology is inadequate. We collected ~300 000 samples mosquitoes 15 representative regions within Yunnan, China. Using as reference vectors, we designed a comparative virome strategy to study composition, diversity, hosts spatiotemporal distribution Culicoides. A map viromes Yunan province, China, was constructed. At same locations,...
Jingmen tick virus (JMTV) is a novel tick-borne segmented RNA that closely related to un-segmental in evolution. It has been confirmed JMTV could be causative agent of human disease. In this study, total 3658 ticks were sampled from 7 provinces China and then divided into 545 pools according the location species. QRT-PCR nested PCR performed confirm presence JMTV. The results showed was identified 5 out with an average infection rate 1.4% (51/3658). Phylogenetic analysis indicated all...
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a widespread outbreak of highly pathogenic COVID-19. It is therefore important and timely to characterize interactions between the virus host cell at molecular level understand its disease pathogenesis. To gain insights, we performed high-throughput sequencing that generated time-series data simultaneously for bioinformatics analysis genomes transcriptomes implicated in SARS-CoV-2 infection. Our results showed...